Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C0LGQ5

- GSO1_ARATH

UniProt

C0LGQ5 - GSO1_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

LRR receptor-like serine/threonine-protein kinase GSO1

Gene

GSO1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Together with GSO2, receptor-like serine/threonine-kinase required during the development of the epidermal surface in embryos and cotyledons.1 Publication

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei979 – 9791ATPPROSITE-ProRule annotation
Active sitei1084 – 10841Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi957 – 9659ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. embryo development ending in seed dormancy Source: TAIR
  2. epidermis development Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein, Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G20140-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
LRR receptor-like serine/threonine-protein kinase GSO1 (EC:2.7.11.1)
Alternative name(s):
Protein GASSHO 1
Gene namesi
Name:GSO1
Ordered Locus Names:At4g20140
ORF Names:F1C12.60
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G20140.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini19 – 876858ExtracellularSequence AnalysisAdd
BLAST
Transmembranei877 – 89721HelicalSequence AnalysisAdd
BLAST
Topological domaini898 – 1249352CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Disruption phenotypei

No visible phenotype during embryogenesis and seedling development. Gso1 and gso2 double mutants produce slightly contorted seeds, with abnormally shaped embryos and seedlings; adhesion between cotyledons and the peripheral tissue of the endosperm, short hypocotyl, and concave cotyledons sometimes fused, with compressed epidermal cells, endosperm tissue partially adherent to the surface of the cotyledons, and a rough surface.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 12491231LRR receptor-like serine/threonine-protein kinase GSO1PRO_0000387513Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi77 – 771N-linked (GlcNAc...)Sequence Analysis
Glycosylationi117 – 1171N-linked (GlcNAc...)Sequence Analysis
Glycosylationi213 – 2131N-linked (GlcNAc...)Sequence Analysis
Glycosylationi228 – 2281N-linked (GlcNAc...)Sequence Analysis
Glycosylationi248 – 2481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi298 – 2981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi309 – 3091N-linked (GlcNAc...)Sequence Analysis
Glycosylationi334 – 3341N-linked (GlcNAc...)Sequence Analysis
Glycosylationi369 – 3691N-linked (GlcNAc...)Sequence Analysis
Glycosylationi393 – 3931N-linked (GlcNAc...)Sequence Analysis
Glycosylationi406 – 4061N-linked (GlcNAc...)Sequence Analysis
Glycosylationi454 – 4541N-linked (GlcNAc...)Sequence Analysis
Glycosylationi537 – 5371N-linked (GlcNAc...)Sequence Analysis
Glycosylationi553 – 5531N-linked (GlcNAc...)Sequence Analysis
Glycosylationi558 – 5581N-linked (GlcNAc...)Sequence Analysis
Glycosylationi565 – 5651N-linked (GlcNAc...)Sequence Analysis
Glycosylationi693 – 6931N-linked (GlcNAc...)Sequence Analysis
Glycosylationi708 – 7081N-linked (GlcNAc...)Sequence Analysis
Glycosylationi779 – 7791N-linked (GlcNAc...)Sequence Analysis
Glycosylationi822 – 8221N-linked (GlcNAc...)Sequence Analysis
Modified residuei948 – 9481PhosphothreonineBy similarity
Modified residuei1027 – 10271PhosphotyrosineBy similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiC0LGQ5.
PRIDEiC0LGQ5.

Expressioni

Tissue specificityi

Mostly expressed in siliques, seeds, developing embryos and seedlings, detected in flower buds and roots, but not in leaves or stems.1 Publication

Developmental stagei

In flower buds, localized in filaments and stigmas. During embryogenesis, uniform expression from the globular embryo to the mature cotyledonary embryo. After germination, detected in whole cotyledons and in the hypocotyl.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G20140.1-P.

Structurei

3D structure databases

ProteinModelPortaliC0LGQ5.
SMRiC0LGQ5. Positions 38-852, 861-1249.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati94 – 11825LRR 1Add
BLAST
Repeati119 – 14224LRR 2Add
BLAST
Repeati144 – 16623LRR 3Add
BLAST
Repeati168 – 19023LRR 4Add
BLAST
Repeati191 – 21424LRR 5Add
BLAST
Repeati216 – 23823LRR 6Add
BLAST
Repeati239 – 26224LRR 7Add
BLAST
Repeati264 – 28522LRR 8Add
BLAST
Repeati286 – 31025LRR 9Add
BLAST
Repeati312 – 33423LRR 10Add
BLAST
Repeati336 – 35924LRR 11Add
BLAST
Repeati360 – 38324LRR 12Add
BLAST
Repeati385 – 40723LRR 13Add
BLAST
Repeati408 – 43124LRR 14Add
BLAST
Repeati433 – 45523LRR 15Add
BLAST
Repeati457 – 47923LRR 16Add
BLAST
Repeati480 – 50324LRR 17Add
BLAST
Repeati505 – 52723LRR 18Add
BLAST
Repeati528 – 55124LRR 19Add
BLAST
Repeati553 – 57422LRR 20Add
BLAST
Repeati576 – 59823LRR 21Add
BLAST
Repeati599 – 62224LRR 22Add
BLAST
Repeati623 – 64624LRR 23Add
BLAST
Repeati648 – 67023LRR 24Add
BLAST
Repeati671 – 69424LRR 25Add
BLAST
Repeati696 – 71823LRR 26Add
BLAST
Repeati719 – 74224LRR 27Add
BLAST
Repeati744 – 76623LRR 28Add
BLAST
Repeati767 – 79125LRR 29Add
BLAST
Repeati792 – 81524LRR 30Add
BLAST
Repeati817 – 83822LRR 31Add
BLAST
Domaini951 – 1240290Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 31 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG4886.
HOGENOMiHOG000116551.
InParanoidiC0LGQ5.
OMAiHDKSFAR.
PhylomeDBiC0LGQ5.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR025875. Leu-rich_rpt_4.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00560. LRR_1. 2 hits.
PF12799. LRR_4. 1 hit.
PF13855. LRR_8. 4 hits.
PF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C0LGQ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQPLVLLLLF ILCFSGLGQP GIINNDLQTL LEVKKSLVTN PQEDDPLRQW
60 70 80 90 100
NSDNINYCSW TGVTCDNTGL FRVIALNLTG LGLTGSISPW FGRFDNLIHL
110 120 130 140 150
DLSSNNLVGP IPTALSNLTS LESLFLFSNQ LTGEIPSQLG SLVNIRSLRI
160 170 180 190 200
GDNELVGDIP ETLGNLVNLQ MLALASCRLT GPIPSQLGRL VRVQSLILQD
210 220 230 240 250
NYLEGPIPAE LGNCSDLTVF TAAENMLNGT IPAELGRLEN LEILNLANNS
260 270 280 290 300
LTGEIPSQLG EMSQLQYLSL MANQLQGLIP KSLADLGNLQ TLDLSANNLT
310 320 330 340 350
GEIPEEFWNM SQLLDLVLAN NHLSGSLPKS ICSNNTNLEQ LVLSGTQLSG
360 370 380 390 400
EIPVELSKCQ SLKQLDLSNN SLAGSIPEAL FELVELTDLY LHNNTLEGTL
410 420 430 440 450
SPSISNLTNL QWLVLYHNNL EGKLPKEISA LRKLEVLFLY ENRFSGEIPQ
460 470 480 490 500
EIGNCTSLKM IDMFGNHFEG EIPPSIGRLK ELNLLHLRQN ELVGGLPASL
510 520 530 540 550
GNCHQLNILD LADNQLSGSI PSSFGFLKGL EQLMLYNNSL QGNLPDSLIS
560 570 580 590 600
LRNLTRINLS HNRLNGTIHP LCGSSSYLSF DVTNNGFEDE IPLELGNSQN
610 620 630 640 650
LDRLRLGKNQ LTGKIPWTLG KIRELSLLDM SSNALTGTIP LQLVLCKKLT
660 670 680 690 700
HIDLNNNFLS GPIPPWLGKL SQLGELKLSS NQFVESLPTE LFNCTKLLVL
710 720 730 740 750
SLDGNSLNGS IPQEIGNLGA LNVLNLDKNQ FSGSLPQAMG KLSKLYELRL
760 770 780 790 800
SRNSLTGEIP VEIGQLQDLQ SALDLSYNNF TGDIPSTIGT LSKLETLDLS
810 820 830 840 850
HNQLTGEVPG SVGDMKSLGY LNVSFNNLGG KLKKQFSRWP ADSFLGNTGL
860 870 880 890 900
CGSPLSRCNR VRSNNKQQGL SARSVVIISA ISALTAIGLM ILVIALFFKQ
910 920 930 940 950
RHDFFKKVGH GSTAYTSSSS SSQATHKPLF RNGASKSDIR WEDIMEATHN
960 970 980 990 1000
LSEEFMIGSG GSGKVYKAEL ENGETVAVKK ILWKDDLMSN KSFSREVKTL
1010 1020 1030 1040 1050
GRIRHRHLVK LMGYCSSKSE GLNLLIYEYM KNGSIWDWLH EDKPVLEKKK
1060 1070 1080 1090 1100
KLLDWEARLR IAVGLAQGVE YLHHDCVPPI VHRDIKSSNV LLDSNMEAHL
1110 1120 1130 1140 1150
GDFGLAKVLT ENCDTNTDSN TWFACSYGYI APEYAYSLKA TEKSDVYSMG
1160 1170 1180 1190 1200
IVLMEIVTGK MPTDSVFGAE MDMVRWVETH LEVAGSARDK LIDPKLKPLL
1210 1220 1230 1240
PFEEDAACQV LEIALQCTKT SPQERPSSRQ ACDSLLHVYN NRTAGYKKL
Length:1,249
Mass (Da):137,288
Last modified:May 5, 2009 - v1
Checksum:i9B4C4928C8A10E95
GO

Sequence cautioni

The sequence CAA18239.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAB79014.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022224 Genomic DNA. Translation: CAA18239.1. Sequence problems.
AL161552 Genomic DNA. Translation: CAB79014.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84279.1.
FJ708746 mRNA. Translation: ACN59340.1.
PIRiT05322.
RefSeqiNP_193747.2. NM_118133.2.
UniGeneiAt.2179.
At.22288.

Genome annotation databases

EnsemblPlantsiAT4G20140.1; AT4G20140.1; AT4G20140.
GeneIDi827760.
KEGGiath:AT4G20140.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022224 Genomic DNA. Translation: CAA18239.1 . Sequence problems.
AL161552 Genomic DNA. Translation: CAB79014.1 . Sequence problems.
CP002687 Genomic DNA. Translation: AEE84279.1 .
FJ708746 mRNA. Translation: ACN59340.1 .
PIRi T05322.
RefSeqi NP_193747.2. NM_118133.2.
UniGenei At.2179.
At.22288.

3D structure databases

ProteinModelPortali C0LGQ5.
SMRi C0LGQ5. Positions 38-852, 861-1249.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT4G20140.1-P.

Proteomic databases

PaxDbi C0LGQ5.
PRIDEi C0LGQ5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT4G20140.1 ; AT4G20140.1 ; AT4G20140 .
GeneIDi 827760.
KEGGi ath:AT4G20140.

Organism-specific databases

GeneFarmi 663. 55.
TAIRi AT4G20140.

Phylogenomic databases

eggNOGi COG4886.
HOGENOMi HOG000116551.
InParanoidi C0LGQ5.
OMAi HDKSFAR.
PhylomeDBi C0LGQ5.

Enzyme and pathway databases

BioCyci ARA:AT4G20140-MONOMER.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR025875. Leu-rich_rpt_4.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00560. LRR_1. 2 hits.
PF12799. LRR_4. 1 hit.
PF13855. LRR_8. 4 hits.
PF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
    Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
    BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "GASSHO1 and GASSHO2 encoding a putative leucine-rich repeat transmembrane-type receptor kinase are essential for the normal development of the epidermal surface in Arabidopsis embryos."
    Tsuwamoto R., Fukuoka H., Takahata Y.
    Plant J. 54:30-42(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE, DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.

Entry informationi

Entry nameiGSO1_ARATH
AccessioniPrimary (citable) accession number: C0LGQ5
Secondary accession number(s): Q9SN91
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3