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C0LGQ4 (MRH1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable LRR receptor-like serine/threonine-protein kinase MRH1

EC=2.7.11.1
Alternative name(s):
Protein MORPHOGENESIS OF ROOT HAIR 1
Gene names
Name:MRH1
Ordered Locus Names:At4g18640
ORF Names:F28A21.50
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length678 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in the regulation of root hairs development. Ref.4

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Membrane; Single-pass type I membrane protein Potential.

Disruption phenotype

Short straight root hairs. Ref.4

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 4 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Sequence caution

The sequence CAB37449.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAB78866.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 678653Probable LRR receptor-like serine/threonine-protein kinase MRH1
PRO_0000387516

Regions

Topological domain26 – 323298Extracellular Potential
Transmembrane324 – 34421Helical; Potential
Topological domain345 – 678334Cytoplasmic Potential
Repeat71 – 9424LRR 1
Repeat95 – 11723LRR 2
Repeat119 – 14123LRR 3
Repeat143 – 16422LRR 4
Domain346 – 651306Protein kinase

Amino acid modifications

Glycosylation521N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
C0LGQ4 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 4D792304B01F4C13

FASTA67875,820
        10         20         30         40         50         60 
MMGCGFHFPW FFFLIIGLQA PLSLSLTSQG SALLKFRARV NSDPHGTLAN WNVSGINDLC 

        70         80         90        100        110        120 
YWSGVTCVDG KVQILDLSGY SLEGTLAPEL SQLSDLRSLI LSRNHFSGGI PKEYGSFENL 

       130        140        150        160        170        180 
EVLDLRENDL SGQIPPELSN GLSLKHLLLS GNKFSDDMRI KIVRLQSSYE VRLKKSPKLS 

       190        200        210        220        230        240 
PLAVLGCINR KLGHCVSRNR IIQVKKVEAI VFRIKATSRR FLKAFPSFLE ETDIYKRREL 

       250        260        270        280        290        300 
LEETSNLAAE PAPSAPSPSP GIITEASPRS SGSFPAVTNA KKRRPPLVPP VPSPDKGSTS 

       310        320        330        340        350        360 
PDISKNQPQD NKQSKGSKHV WLYVVIAVAS FVGLLIIVAV IFFCRKRAVK SIGPWKTGLS 

       370        380        390        400        410        420 
GQLQKAFVTG VPKLNRSELE TACEDFSNII ETFDGYTVYK GTLSSGVEIA VASTAIAESK 

       430        440        450        460        470        480 
EWTRAMEMAY RRKIDTLSRI NHKNFVNLIG YCEEDDPFNR MMVFEYAPNG TLFEHLHDKE 

       490        500        510        520        530        540 
TEHLDWSARM RIIMGTAYCL QHMHGMNPPM AHTDFNSSEI YLTDDYAAKV SEIPFNLEAR 

       550        560        570        580        590        600 
LNPKKHVSGD LEQTSLLLPP EPEANVHSFG VLMLEIISGK LSFSDEYGSI EQWASKYLEK 

       610        620        630        640        650        660 
DDLGEMIDPS LKTFKEEELE VICDVIRECL KTEQRQRPSM KDVAEQLKQV INITPEKATP 

       670 
RSSPLWWAEL EILSSEAT 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Analysis of the root-hair morphogenesis transcriptome reveals the molecular identity of six genes with roles in root-hair development in Arabidopsis."
Jones M.A., Raymond M.J., Smirnoff N.
Plant J. 45:83-100(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, DISRUPTION PHENOTYPE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL035526 Genomic DNA. Translation: CAB37449.1. Sequence problems.
AL161549 Genomic DNA. Translation: CAB78866.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84071.1.
FJ708745 mRNA. Translation: ACN59339.1.
PIRT04856.
RefSeqNP_193599.3. NM_117980.4.
UniGeneAt.32880.

3D structure databases

ProteinModelPortalC0LGQ4.
SMRC0LGQ4. Positions 26-292, 373-654.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT4G18640.1-P.

Proteomic databases

PaxDbC0LGQ4.
PRIDEC0LGQ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G18640.1; AT4G18640.1; AT4G18640.
GeneID827598.
KEGGath:AT4G18640.

Organism-specific databases

GeneFarm2334. 50.
TAIRAT4G18640.

Phylogenomic databases

eggNOGNOG271462.
HOGENOMHOG000240929.
InParanoidQ9M0L9.
OMAMEMAYRR.
PhylomeDBC0LGQ4.

Enzyme and pathway databases

BioCycARA:AT4G18640-MONOMER.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR025875. Leu-rich_rpt_4.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamPF12799. LRR_4. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMRH1_ARATH
AccessionPrimary (citable) accession number: C0LGQ4
Secondary accession number(s): Q9M0L9, Q9SN49
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: June 11, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names