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C0LGQ4

- MRH1_ARATH

UniProt

C0LGQ4 - MRH1_ARATH

Protein

Probable LRR receptor-like serine/threonine-protein kinase MRH1

Gene

MRH1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (05 May 2009)
      Previous versions | rss
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    Functioni

    May be involved in the regulation of root hairs development.1 Publication

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. root hair cell differentiation Source: TAIR

    Keywords - Molecular functioni

    Kinase, Receptor, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT4G18640-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable LRR receptor-like serine/threonine-protein kinase MRH1 (EC:2.7.11.1)
    Alternative name(s):
    Protein MORPHOGENESIS OF ROOT HAIR 1
    Gene namesi
    Name:MRH1
    Ordered Locus Names:At4g18640
    ORF Names:F28A21.50
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 4

    Organism-specific databases

    TAIRiAT4G18640.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Disruption phenotypei

    Short straight root hairs.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 678653Probable LRR receptor-like serine/threonine-protein kinase MRH1PRO_0000387516Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi52 – 521N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiC0LGQ4.
    PRIDEiC0LGQ4.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT4G18640.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliC0LGQ4.
    SMRiC0LGQ4. Positions 26-292, 373-654.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini26 – 323298ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini345 – 678334CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei324 – 34421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati71 – 9424LRR 1Add
    BLAST
    Repeati95 – 11723LRR 2Add
    BLAST
    Repeati119 – 14123LRR 3Add
    BLAST
    Repeati143 – 16422LRR 4Add
    BLAST
    Domaini346 – 651306Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 4 LRR (leucine-rich) repeats.Curated
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG271462.
    HOGENOMiHOG000240929.
    InParanoidiQ9M0L9.
    OMAiMEMAYRR.
    PhylomeDBiC0LGQ4.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR025875. Leu-rich_rpt_4.
    IPR013210. LRR-contain_N2.
    IPR000719. Prot_kinase_dom.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    [Graphical view]
    PfamiPF12799. LRR_4. 1 hit.
    PF08263. LRRNT_2. 1 hit.
    PF07714. Pkinase_Tyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    C0LGQ4-1 [UniParc]FASTAAdd to Basket

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    MMGCGFHFPW FFFLIIGLQA PLSLSLTSQG SALLKFRARV NSDPHGTLAN    50
    WNVSGINDLC YWSGVTCVDG KVQILDLSGY SLEGTLAPEL SQLSDLRSLI 100
    LSRNHFSGGI PKEYGSFENL EVLDLRENDL SGQIPPELSN GLSLKHLLLS 150
    GNKFSDDMRI KIVRLQSSYE VRLKKSPKLS PLAVLGCINR KLGHCVSRNR 200
    IIQVKKVEAI VFRIKATSRR FLKAFPSFLE ETDIYKRREL LEETSNLAAE 250
    PAPSAPSPSP GIITEASPRS SGSFPAVTNA KKRRPPLVPP VPSPDKGSTS 300
    PDISKNQPQD NKQSKGSKHV WLYVVIAVAS FVGLLIIVAV IFFCRKRAVK 350
    SIGPWKTGLS GQLQKAFVTG VPKLNRSELE TACEDFSNII ETFDGYTVYK 400
    GTLSSGVEIA VASTAIAESK EWTRAMEMAY RRKIDTLSRI NHKNFVNLIG 450
    YCEEDDPFNR MMVFEYAPNG TLFEHLHDKE TEHLDWSARM RIIMGTAYCL 500
    QHMHGMNPPM AHTDFNSSEI YLTDDYAAKV SEIPFNLEAR LNPKKHVSGD 550
    LEQTSLLLPP EPEANVHSFG VLMLEIISGK LSFSDEYGSI EQWASKYLEK 600
    DDLGEMIDPS LKTFKEEELE VICDVIRECL KTEQRQRPSM KDVAEQLKQV 650
    INITPEKATP RSSPLWWAEL EILSSEAT 678
    Length:678
    Mass (Da):75,820
    Last modified:May 5, 2009 - v1
    Checksum:i4D792304B01F4C13
    GO

    Sequence cautioni

    The sequence CAB37449.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAB78866.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL035526 Genomic DNA. Translation: CAB37449.1. Sequence problems.
    AL161549 Genomic DNA. Translation: CAB78866.1. Sequence problems.
    CP002687 Genomic DNA. Translation: AEE84071.1.
    FJ708745 mRNA. Translation: ACN59339.1.
    PIRiT04856.
    RefSeqiNP_193599.3. NM_117980.4.
    UniGeneiAt.32880.

    Genome annotation databases

    EnsemblPlantsiAT4G18640.1; AT4G18640.1; AT4G18640.
    GeneIDi827598.
    KEGGiath:AT4G18640.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL035526 Genomic DNA. Translation: CAB37449.1 . Sequence problems.
    AL161549 Genomic DNA. Translation: CAB78866.1 . Sequence problems.
    CP002687 Genomic DNA. Translation: AEE84071.1 .
    FJ708745 mRNA. Translation: ACN59339.1 .
    PIRi T04856.
    RefSeqi NP_193599.3. NM_117980.4.
    UniGenei At.32880.

    3D structure databases

    ProteinModelPortali C0LGQ4.
    SMRi C0LGQ4. Positions 26-292, 373-654.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT4G18640.1-P.

    Proteomic databases

    PaxDbi C0LGQ4.
    PRIDEi C0LGQ4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT4G18640.1 ; AT4G18640.1 ; AT4G18640 .
    GeneIDi 827598.
    KEGGi ath:AT4G18640.

    Organism-specific databases

    GeneFarmi 2334. 50.
    TAIRi AT4G18640.

    Phylogenomic databases

    eggNOGi NOG271462.
    HOGENOMi HOG000240929.
    InParanoidi Q9M0L9.
    OMAi MEMAYRR.
    PhylomeDBi C0LGQ4.

    Enzyme and pathway databases

    BioCyci ARA:AT4G18640-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR025875. Leu-rich_rpt_4.
    IPR013210. LRR-contain_N2.
    IPR000719. Prot_kinase_dom.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    [Graphical view ]
    Pfami PF12799. LRR_4. 1 hit.
    PF08263. LRRNT_2. 1 hit.
    PF07714. Pkinase_Tyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
      Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
      , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
      Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
      Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
      BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Analysis of the root-hair morphogenesis transcriptome reveals the molecular identity of six genes with roles in root-hair development in Arabidopsis."
      Jones M.A., Raymond M.J., Smirnoff N.
      Plant J. 45:83-100(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiMRH1_ARATH
    AccessioniPrimary (citable) accession number: C0LGQ4
    Secondary accession number(s): Q9M0L9, Q9SN49
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 3, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3