Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable LRR receptor-like serine/threonine-protein kinase MRH1

Gene

MRH1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the regulation of root hairs development.1 Publication

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. root hair cell differentiation Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G18640-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable LRR receptor-like serine/threonine-protein kinase MRH1 (EC:2.7.11.1)
Alternative name(s):
Protein MORPHOGENESIS OF ROOT HAIR 1
Gene namesi
Name:MRH1
Ordered Locus Names:At4g18640
ORF Names:F28A21.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G18640.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini26 – 323298ExtracellularSequence AnalysisAdd
BLAST
Transmembranei324 – 34421HelicalSequence AnalysisAdd
BLAST
Topological domaini345 – 678334CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Disruption phenotypei

Short straight root hairs.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 678653Probable LRR receptor-like serine/threonine-protein kinase MRH1PRO_0000387516Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi52 – 521N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiC0LGQ4.
PRIDEiC0LGQ4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G18640.1-P.

Structurei

3D structure databases

ProteinModelPortaliC0LGQ4.
SMRiC0LGQ4. Positions 29-197, 357-654.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati71 – 9424LRR 1Add
BLAST
Repeati95 – 11723LRR 2Add
BLAST
Repeati119 – 14123LRR 3Add
BLAST
Repeati143 – 16422LRR 4Add
BLAST
Domaini346 – 651306Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 4 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG271462.
HOGENOMiHOG000240929.
InParanoidiC0LGQ4.
OMAiIICELIQ.
PhylomeDBiC0LGQ4.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR025875. Leu-rich_rpt_4.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF12799. LRR_4. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C0LGQ4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMGCGFHFPW FFFLIIGLQA PLSLSLTSQG SALLKFRARV NSDPHGTLAN
60 70 80 90 100
WNVSGINDLC YWSGVTCVDG KVQILDLSGY SLEGTLAPEL SQLSDLRSLI
110 120 130 140 150
LSRNHFSGGI PKEYGSFENL EVLDLRENDL SGQIPPELSN GLSLKHLLLS
160 170 180 190 200
GNKFSDDMRI KIVRLQSSYE VRLKKSPKLS PLAVLGCINR KLGHCVSRNR
210 220 230 240 250
IIQVKKVEAI VFRIKATSRR FLKAFPSFLE ETDIYKRREL LEETSNLAAE
260 270 280 290 300
PAPSAPSPSP GIITEASPRS SGSFPAVTNA KKRRPPLVPP VPSPDKGSTS
310 320 330 340 350
PDISKNQPQD NKQSKGSKHV WLYVVIAVAS FVGLLIIVAV IFFCRKRAVK
360 370 380 390 400
SIGPWKTGLS GQLQKAFVTG VPKLNRSELE TACEDFSNII ETFDGYTVYK
410 420 430 440 450
GTLSSGVEIA VASTAIAESK EWTRAMEMAY RRKIDTLSRI NHKNFVNLIG
460 470 480 490 500
YCEEDDPFNR MMVFEYAPNG TLFEHLHDKE TEHLDWSARM RIIMGTAYCL
510 520 530 540 550
QHMHGMNPPM AHTDFNSSEI YLTDDYAAKV SEIPFNLEAR LNPKKHVSGD
560 570 580 590 600
LEQTSLLLPP EPEANVHSFG VLMLEIISGK LSFSDEYGSI EQWASKYLEK
610 620 630 640 650
DDLGEMIDPS LKTFKEEELE VICDVIRECL KTEQRQRPSM KDVAEQLKQV
660 670
INITPEKATP RSSPLWWAEL EILSSEAT
Length:678
Mass (Da):75,820
Last modified:May 5, 2009 - v1
Checksum:i4D792304B01F4C13
GO

Sequence cautioni

The sequence CAB37449.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAB78866.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035526 Genomic DNA. Translation: CAB37449.1. Sequence problems.
AL161549 Genomic DNA. Translation: CAB78866.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84071.1.
FJ708745 mRNA. Translation: ACN59339.1.
PIRiT04856.
RefSeqiNP_193599.3. NM_117980.4.
UniGeneiAt.32880.

Genome annotation databases

EnsemblPlantsiAT4G18640.1; AT4G18640.1; AT4G18640.
GeneIDi827598.
KEGGiath:AT4G18640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035526 Genomic DNA. Translation: CAB37449.1. Sequence problems.
AL161549 Genomic DNA. Translation: CAB78866.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84071.1.
FJ708745 mRNA. Translation: ACN59339.1.
PIRiT04856.
RefSeqiNP_193599.3. NM_117980.4.
UniGeneiAt.32880.

3D structure databases

ProteinModelPortaliC0LGQ4.
SMRiC0LGQ4. Positions 29-197, 357-654.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G18640.1-P.

Proteomic databases

PaxDbiC0LGQ4.
PRIDEiC0LGQ4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G18640.1; AT4G18640.1; AT4G18640.
GeneIDi827598.
KEGGiath:AT4G18640.

Organism-specific databases

GeneFarmi2334. 50.
TAIRiAT4G18640.

Phylogenomic databases

eggNOGiNOG271462.
HOGENOMiHOG000240929.
InParanoidiC0LGQ4.
OMAiIICELIQ.
PhylomeDBiC0LGQ4.

Enzyme and pathway databases

BioCyciARA:AT4G18640-MONOMER.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR025875. Leu-rich_rpt_4.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF12799. LRR_4. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
    Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
    BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Analysis of the root-hair morphogenesis transcriptome reveals the molecular identity of six genes with roles in root-hair development in Arabidopsis."
    Jones M.A., Raymond M.J., Smirnoff N.
    Plant J. 45:83-100(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.

Entry informationi

Entry nameiMRH1_ARATH
AccessioniPrimary (citable) accession number: C0LGQ4
Secondary accession number(s): Q9M0L9, Q9SN49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: January 7, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.