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C0LGP4 (Y3475_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable LRR receptor-like serine/threonine-protein kinase At3g47570

EC=2.7.11.1
Gene names
Ordered Locus Names:At3g47570
ORF Names:F1P2.120
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length1010 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 21 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Sequence caution

The sequence CAB61983.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 1010991Probable LRR receptor-like serine/threonine-protein kinase At3g47570
PRO_0000387551

Regions

Topological domain20 – 645626Extracellular Potential
Transmembrane646 – 66621Helical; Potential
Topological domain667 – 1010344Cytoplasmic Potential
Repeat89 – 11325LRR 1
Repeat114 – 13724LRR 2
Repeat139 – 16123LRR 3
Repeat162 – 18524LRR 4
Repeat186 – 20924LRR 5
Repeat211 – 23323LRR 6
Repeat234 – 25825LRR 7
Repeat259 – 28224LRR 8
Repeat283 – 30725LRR 9
Repeat310 – 33324LRR 10
Repeat335 – 35925LRR 11
Repeat361 – 38424LRR 12
Repeat385 – 40824LRR 13
Repeat410 – 43223LRR 14
Repeat433 – 45523LRR 15
Repeat457 – 48024LRR 16
Repeat481 – 50424LRR 17
Repeat505 – 52824LRR 18
Repeat530 – 55122LRR 19
Repeat552 – 57423LRR 20
Repeat575 – 60026LRR 21
Domain702 – 1002301Protein kinase
Nucleotide binding708 – 7169ATP By similarity

Sites

Active site8391Proton acceptor By similarity
Binding site7311ATP By similarity

Amino acid modifications

Modified residue6991Phosphothreonine By similarity
Modified residue7811Phosphotyrosine By similarity
Glycosylation481N-linked (GlcNAc...) Potential
Glycosylation881N-linked (GlcNAc...) Potential
Glycosylation1361N-linked (GlcNAc...) Potential
Glycosylation1841N-linked (GlcNAc...) Potential
Glycosylation2211N-linked (GlcNAc...) Potential
Glycosylation2321N-linked (GlcNAc...) Potential
Glycosylation2811N-linked (GlcNAc...) Potential
Glycosylation2941N-linked (GlcNAc...) Potential
Glycosylation3341N-linked (GlcNAc...) Potential
Glycosylation3581N-linked (GlcNAc...) Potential
Glycosylation4311N-linked (GlcNAc...) Potential
Glycosylation4551N-linked (GlcNAc...) Potential
Glycosylation4701N-linked (GlcNAc...) Potential
Glycosylation5821N-linked (GlcNAc...) Potential
Glycosylation6001N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict9951I → V in AAL36369. Ref.3

Sequences

Sequence LengthMass (Da)Tools
C0LGP4 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 5B06436E11E9F879

FASTA1,010110,901
        10         20         30         40         50         60 
MRLFLLLAFN ALMLLETHGF TDETDRQALL QFKSQVSEDK RVVLSSWNHS FPLCNWKGVT 

        70         80         90        100        110        120 
CGRKNKRVTH LELGRLQLGG VISPSIGNLS FLVSLDLYEN FFGGTIPQEV GQLSRLEYLD 

       130        140        150        160        170        180 
MGINYLRGPI PLGLYNCSRL LNLRLDSNRL GGSVPSELGS LTNLVQLNLY GNNMRGKLPT 

       190        200        210        220        230        240 
SLGNLTLLEQ LALSHNNLEG EIPSDVAQLT QIWSLQLVAN NFSGVFPPAL YNLSSLKLLG 

       250        260        270        280        290        300 
IGYNHFSGRL RPDLGILLPN LLSFNMGGNY FTGSIPTTLS NISTLERLGM NENNLTGSIP 

       310        320        330        340        350        360 
TFGNVPNLKL LFLHTNSLGS DSSRDLEFLT SLTNCTQLET LGIGRNRLGG DLPISIANLS 

       370        380        390        400        410        420 
AKLVTLDLGG TLISGSIPYD IGNLINLQKL ILDQNMLSGP LPTSLGKLLN LRYLSLFSNR 

       430        440        450        460        470        480 
LSGGIPAFIG NMTMLETLDL SNNGFEGIVP TSLGNCSHLL ELWIGDNKLN GTIPLEIMKI 

       490        500        510        520        530        540 
QQLLRLDMSG NSLIGSLPQD IGALQNLGTL SLGDNKLSGK LPQTLGNCLT MESLFLEGNL 

       550        560        570        580        590        600 
FYGDIPDLKG LVGVKEVDLS NNDLSGSIPE YFASFSKLEY LNLSFNNLEG KVPVKGIFEN 

       610        620        630        640        650        660 
ATTVSIVGNN DLCGGIMGFQ LKPCLSQAPS VVKKHSSRLK KVVIGVSVGI TLLLLLFMAS 

       670        680        690        700        710        720 
VTLIWLRKRK KNKETNNPTP STLEVLHEKI SYGDLRNATN GFSSSNMVGS GSFGTVYKAL 

       730        740        750        760        770        780 
LLTEKKVVAV KVLNMQRRGA MKSFMAECES LKDIRHRNLV KLLTACSSID FQGNEFRALI 

       790        800        810        820        830        840 
YEFMPNGSLD MWLHPEEVEE IHRPSRTLTL LERLNIAIDV ASVLDYLHVH CHEPIAHCDL 

       850        860        870        880        890        900 
KPSNVLLDDD LTAHVSDFGL ARLLLKFDEE SFFNQLSSAG VRGTIGYAAP EYGVGGQPSI 

       910        920        930        940        950        960 
NGDVYSFGIL LLEMFTGKRP TNELFGGNFT LNSYTKSALP ERILDIVDES ILHIGLRVGF 

       970        980        990       1000       1010 
PVVECLTMVF EVGLRCCEES PMNRLATSIV VKELISIRER FFKASRTTWR 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL132955 Genomic DNA. Translation: CAB61983.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE78303.1.
AY064013 mRNA. Translation: AAL36369.1.
FJ708735 mRNA. Translation: ACN59329.1.
PIRT45717.
RefSeqNP_566892.1. NM_114625.2.
UniGeneAt.523.

3D structure databases

ProteinModelPortalC0LGP4.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbC0LGP4.
PRIDEC0LGP4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G47570.1; AT3G47570.1; AT3G47570.
GeneID823911.
KEGGath:AT3G47570.

Organism-specific databases

GeneFarm673. 56.
TAIRAT3G47570.

Phylogenomic databases

eggNOGCOG4886.
HOGENOMHOG000116551.
InParanoidQ8VZM3.
OMATAETENC.
PhylomeDBC0LGP4.

Enzyme and pathway databases

BioCycARA:AT3G47570-MONOMER.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR025875. Leu-rich_rpt_4.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00560. LRR_1. 1 hit.
PF12799. LRR_4. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY3475_ARATH
AccessionPrimary (citable) accession number: C0LGP4
Secondary accession number(s): Q8VZM3, Q9SN81
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names