C0LGI5 (Y1699_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable LRR receptor-like serine/threonine-protein kinase At1g69990
EC=2.7.11.1

Gene names

Ordered Locus Names:	At1g69990
ORF Names:	F20P5.27

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	591 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein.
Subcellular location	Membrane; Single-pass type I membrane protein Potential.
Sequence similarities	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 5 LRR (leucine-rich) repeats. Contains 1 protein kinase domain.
Sequence caution	The sequence AAB61113.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Membrane
Domain	Leucine-rich repeat Repeat Signal Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Receptor Serine/threonine-protein kinase Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 591	573	Probable LRR receptor-like serine/threonine-protein kinase At1g69990		PRO_0000387541
Regions
	Topological domain	19 – 218	200	Extracellular Potential
	Transmembrane	219 – 239	21	Helical; Potential
	Topological domain	240 – 591	352	Cytoplasmic Potential
	Repeat	66 – 88	23	LRR 1
	Repeat	90 – 111	22	LRR 2
	Repeat	115 – 137	23	LRR 3
	Repeat	139 – 162	24	LRR 4
	Repeat	163 – 185	23	LRR 5
	Domain	295 – 573	279	Protein kinase
	Nucleotide binding	301 – 309	9	ATP By similarity
Sites
	Binding site	323	1	ATP By similarity
Amino acid modifications
	Glycosylation	46	1	N-linked (GlcNAc...) Potential
	Glycosylation	211	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	C0LGI5 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: D3AF9B8A24DABFB0	FASTA	591	65,553
	10 20 30 40 50 60 MKTISIFFVI ILMSSSHAED DVLCLKGFKS SLKDPSNQLN TWSFPNSSSS ICKLTGVSCW 70 80 90 100 110 120 NAKENRILSL QLQSMQLSGQ IPESLKLCRS LQSLDLSFND FSGLIPSQIC SWLPYLVTLD 130 140 150 160 170 180 LSGNKLSGSI PSQIVDCKFL NSLALNQNKL TGSIPSELTR LNRLQRLSLA DNDLSGSIPS 190 200 210 220 230 240 ELSHYGEDGF RGNGGLCGKP LSNCGSFNGK NLTIIVTAGV IGAVGSLCVG FGMFWWFFIR 250 260 270 280 290 300 DRRKMNNYGY GAGKCKDDSD WIGLLRSHKL VQVTLFQKPI VKIKLVDLIE ATNGFDSGNI 310 320 330 340 350 360 VVSSRSGVSY KADLPDGSTL EVKRLSSCCE LSEKQFRSEI NKLGQIRHPN LVPLLGFCVV 370 380 390 400 410 420 EDEILLVYKH MANGTLYSQL QQWDIDWPTR VRVAVGAARG LAWLHHGCQP LYMHQYISSN 430 440 450 460 470 480 VILLDEDFDA RVIDYGLGKL VSSQDSKDSS FSNGKFGYVA PEYSSTMVAS LSGDVYGFGI 490 500 510 520 530 540 VLLEIVTGQK PVLINNGEEG FKESLVEWVS KHLSNGRSKD AIDRRIFGKG YDDEIMQVLR 550 560 570 580 590 IACSCVVSRP KERPLMIQVY ESLKNLGDQH GFFSEYSDEF PLIFNKQEHL K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana." Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J. BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.

Web resources

PlantP kinase Classification PPC

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC002062 Genomic DNA. Translation: AAB61113.1. Sequence problems. CP002684 Genomic DNA. Translation: AEE35006.1. FJ708675 mRNA. Translation: ACN59270.1.
IPI	IPI00529017.
PIR	E96722.
RefSeq	NP_177157.1. NM_105668.1.
UniGene	At.66124.
3D structure databases
ProteinModelPortal	C0LGI5.
SMR	C0LGI5. Positions 27-227, 282-567.
ModBase	Search...
Proteomic databases
PaxDb	C0LGI5.
PRIDE	C0LGI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G69990.1; AT1G69990.1; AT1G69990.
GeneID	843336.
KEGG	ath:AT1G69990.
Organism-specific databases
GeneFarm	2513. 54.
TAIR	At1g69990.
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000116554.
InParanoid	O04545.
OMA	KERPLMI.
PhylomeDB	C0LGI5.
ProtClustDB	CLSN2913573.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR001611. Leu-rich_rpt. IPR013210. LRR-contain_N2. IPR000719. Prot_kinase_cat_dom. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. [Graphical view]
Pfam	PF00560. LRR_1. 2 hits. PF08263. LRRNT_2. 1 hit. PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y1699_ARATH

Accession

Primary (citable) accession number: C0LGI5
Secondary accession number(s): O04545

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 3, 2009
Last sequence update:	May 5, 2009
Last modified:	May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program