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C0LGH8 (Y1634_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable LRR receptor-like serine/threonine-protein kinase At1g63430

EC=2.7.11.1
Gene names
Ordered Locus Names:At1g63430
ORF Names:F2K11.19
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length664 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 4 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAF19706.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: C0LGH8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 664642Probable LRR receptor-like serine/threonine-protein kinase At1g63430
PRO_0000387538

Regions

Topological domain23 – 288266Extracellular Potential
Transmembrane289 – 30921Helical; Potential
Topological domain310 – 664355Cytoplasmic Potential
Repeat94 – 11623LRR 1
Repeat118 – 14023LRR 2
Repeat142 – 16524LRR 3
Repeat166 – 17813LRR 4
Domain360 – 642283Protein kinase

Amino acid modifications

Glycosylation751N-linked (GlcNAc...) Potential
Glycosylation1971N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict501N → D in BAC42570. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 8520F165DA7CB366

FASTA66473,910
        10         20         30         40         50         60 
MRSKYFCSLA LVLGLFFVSC DGFASNEVQA LRRFKEAIYE DPLLVMSNWN DPNSDPCDWT 

        70         80         90        100        110        120 
GIYCSPSKDH VIKINISASS IKGFLAPELG QITYLQELIL HGNILIGTIP KEIGNLKNLK 

       130        140        150        160        170        180 
ILDLGNNHLM GPIPAEIGSL SGIMIINLQS NGLTGKLPAE LGNLKYLREL HIDRNRLQGS 

       190        200        210        220        230        240 
LLVAGASGYQ SKVYSSNSSA NIAGLCKSLK VADFSYNFFV GNIPKCLENL PRTSFQGNCM 

       250        260        270        280        290        300 
QNKDLKHRSS SQCANAQLVK THGSPSAAPK HQSAQMVAKH HRASKPKWLL ALEIVTGSMV 

       310        320        330        340        350        360 
GLLLLVALFS AVHRWNNRST LIIPWKKSSS EKEKFTVYVD SEMLKDVSRL TRQELEVACE 

       370        380        390        400        410        420 
DFSNIIGLSA DSQIYKGTLK GGSEIAVISL CVKEEDWTGY LELYFQREVA DLARLNHENT 

       430        440        450        460        470        480 
AKLLGYCKEI SPFTRMLVFE YASNGTLYEH LHYGEAALVS WARRMKIVIG IARGLKYLHM 

       490        500        510        520        530        540 
ELDPPFTISE LSSNAIYLTE DFTPKLVDFE CWKTILARSE KNLRNISSQG SICVLPNGME 

       550        560        570        580        590        600 
SRYLDVSGNI YAFGILLLEI VSGRPPYCKD KGFLIEWAKE FLEAPEAMSG LVDPELKHFN 

       610        620        630        640        650        660 
QEDLETVCEV ASQCLNRDPT NNNNNHNKPS VQELCETLES RISLSISAEL RSSSLAWAEL 


ALDS 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC008047 Genomic DNA. Translation: AAF19706.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34098.1.
AK117932 mRNA. Translation: BAC42570.1.
FJ708668 mRNA. Translation: ACN59263.1.
RefSeqNP_176532.2. NM_105022.2.
UniGeneAt.14999.

3D structure databases

ProteinModelPortalC0LGH8.
SMRC0LGH8. Positions 26-238, 366-638.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G63430.1-P.

Proteomic databases

PRIDEC0LGH8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G63430.1; AT1G63430.1; AT1G63430. [C0LGH8-1]
GeneID842649.
KEGGath:AT1G63430.

Organism-specific databases

GeneFarm693. 50.
TAIRAT1G63430.

Phylogenomic databases

eggNOGNOG305556.
HOGENOMHOG000240929.
InParanoidQ8GY10.
PhylomeDBC0LGH8.
ProtClustDBCLSN2686223.

Enzyme and pathway databases

BioCycARA:AT1G63430-MONOMER.
ARA:GQT-2270-MONOMER.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamPF00560. LRR_1. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY1634_ARATH
AccessionPrimary (citable) accession number: C0LGH8
Secondary accession number(s): Q8GY10, Q9SH29
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: April 16, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names