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Protein

Probable LRR receptor-like serine/threonine-protein kinase At1g63430

Gene

At1g63430

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Receptor, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable LRR receptor-like serine/threonine-protein kinase At1g63430 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:At1g63430
ORF Names:F2K11.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G63430

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini23 – 288ExtracellularSequence analysisAdd BLAST266
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Topological domaini310 – 664CytoplasmicSequence analysisAdd BLAST355

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000038753823 – 664Probable LRR receptor-like serine/threonine-protein kinase At1g63430Add BLAST642

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi75N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi197N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiC0LGH8
PRIDEiC0LGH8

Expressioni

Gene expression databases

ExpressionAtlasiC0LGH8 baseline and differential
GenevisibleiC0LGH8 AT

Interactioni

Protein-protein interaction databases

BioGridi27870, 1 interactor
STRINGi3702.AT1G63430.2

Structurei

3D structure databases

ProteinModelPortaliC0LGH8
SMRiC0LGH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati94 – 116LRR 1Add BLAST23
Repeati118 – 140LRR 2Add BLAST23
Repeati142 – 165LRR 3Add BLAST24
Repeati166 – 178LRR 4Add BLAST13
Domaini360 – 642Protein kinasePROSITE-ProRule annotationAdd BLAST283

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJP0 Eukaryota
ENOG410YEY6 LUCA
HOGENOMiHOG000240929
InParanoidiC0LGH8
PhylomeDBiC0LGH8

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR013210 LRR_N_plant-typ
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF00560 LRR_1, 1 hit
PF08263 LRRNT_2, 1 hit
PF07714 Pkinase_Tyr, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: C0LGH8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRSKYFCSLA LVLGLFFVSC DGFASNEVQA LRRFKEAIYE DPLLVMSNWN
60 70 80 90 100
DPNSDPCDWT GIYCSPSKDH VIKINISASS IKGFLAPELG QITYLQELIL
110 120 130 140 150
HGNILIGTIP KEIGNLKNLK ILDLGNNHLM GPIPAEIGSL SGIMIINLQS
160 170 180 190 200
NGLTGKLPAE LGNLKYLREL HIDRNRLQGS LLVAGASGYQ SKVYSSNSSA
210 220 230 240 250
NIAGLCKSLK VADFSYNFFV GNIPKCLENL PRTSFQGNCM QNKDLKHRSS
260 270 280 290 300
SQCANAQLVK THGSPSAAPK HQSAQMVAKH HRASKPKWLL ALEIVTGSMV
310 320 330 340 350
GLLLLVALFS AVHRWNNRST LIIPWKKSSS EKEKFTVYVD SEMLKDVSRL
360 370 380 390 400
TRQELEVACE DFSNIIGLSA DSQIYKGTLK GGSEIAVISL CVKEEDWTGY
410 420 430 440 450
LELYFQREVA DLARLNHENT AKLLGYCKEI SPFTRMLVFE YASNGTLYEH
460 470 480 490 500
LHYGEAALVS WARRMKIVIG IARGLKYLHM ELDPPFTISE LSSNAIYLTE
510 520 530 540 550
DFTPKLVDFE CWKTILARSE KNLRNISSQG SICVLPNGME SRYLDVSGNI
560 570 580 590 600
YAFGILLLEI VSGRPPYCKD KGFLIEWAKE FLEAPEAMSG LVDPELKHFN
610 620 630 640 650
QEDLETVCEV ASQCLNRDPT NNNNNHNKPS VQELCETLES RISLSISAEL
660
RSSSLAWAEL ALDS
Length:664
Mass (Da):73,910
Last modified:May 5, 2009 - v1
Checksum:i8520F165DA7CB366
GO

Sequence cautioni

The sequence AAF19706 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti50N → D in BAC42570 (PubMed:11910074).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008047 Genomic DNA Translation: AAF19706.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE34098.1
CP002684 Genomic DNA Translation: ANM58821.1
AK117932 mRNA Translation: BAC42570.1
FJ708668 mRNA Translation: ACN59263.1
RefSeqiNP_001321232.1, NM_001334093.1 [C0LGH8-1]
NP_176532.2, NM_105022.3 [C0LGH8-1]
UniGeneiAt.14999

Genome annotation databases

EnsemblPlantsiAT1G63430.1; AT1G63430.1; AT1G63430 [C0LGH8-1]
AT1G63430.3; AT1G63430.3; AT1G63430 [C0LGH8-1]
GeneIDi842649
GrameneiAT1G63430.1; AT1G63430.1; AT1G63430 [C0LGH8-1]
AT1G63430.3; AT1G63430.3; AT1G63430 [C0LGH8-1]
KEGGiath:AT1G63430

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiY1634_ARATH
AccessioniPrimary (citable) accession number: C0LGH8
Secondary accession number(s): Q8GY10, Q9SH29
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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