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Protein
Submitted name:

Asparagine synthetase

Gene

tsrC

Organism
Streptomyces laurentii
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei2For GATase activityUniRule annotation1
Binding sitei103GlutamineUniRule annotation1
Binding sitei262ATP; via carbonyl oxygenUniRule annotation1
Binding sitei293ATP; via amide nitrogen and carbonyl oxygenUniRule annotation1
Sitei382Important for beta-aspartyl-AMP intermediate formationUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi380 – 381ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid biosynthesis, Asparagine biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Asparagine synthetaseImported
Submitted name:
TsrCImported
Submitted name:
TsrTImported
Gene namesi
Name:tsrCImported
ORF Names:SLA_3875Imported
OrganismiStreptomyces laurentiiImported
Taxonomic identifieri39478 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Structurei

3D structure databases

ProteinModelPortaliC0JRY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 215Glutamine amidotransferase type-2InterPro annotationAdd BLAST214

Keywords - Domaini

Glutamine amidotransferaseUniRule annotation

Family and domain databases

CDDicd01991. Asn_Synthase_B_C. 1 hit.
cd00712. AsnB. 1 hit.
Gene3Di3.40.50.620. 1 hit.
3.60.20.10. 1 hit.
InterProiView protein in InterPro
IPR006426. Asn_synth_AEB.
IPR001962. Asn_synthase.
IPR033738. AsnB_N.
IPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00733. Asn_synthase. 1 hit.
PF13537. GATase_7. 1 hit.
PIRSFiPIRSF001589. Asn_synthetase_glu-h. 1 hit.
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01536. asn_synth_AEB. 1 hit.
PROSITEiView protein in PROSITE
PS51278. GATASE_TYPE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C0JRY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCGIAGWVAF GRDLGAERSA VEAMTRTMAC RGPDAGGTWY GGPVALGHRR
60 70 80 90 100
LAVIDIAGGA QPMLAEENGQ VTAALSYSGE IYGFDELRAR LVSAGHTFRT
110 120 130 140 150
RSDTEVVLRA CLEWGEDVTR HLTGMFAFAL WDARGQELLL IRDRLGVKPL
160 170 180 190 200
YYYPTPDGVL FGSEPKAILA HPEARARLTS DGLRELMTWV NTPGHAIFDG
210 220 230 240 250
MRQVRPGHVV RVARGGITER AYWELPARPH EDDLDTTIGR VRDLLGSSVA
260 270 280 290 300
GQTVADVPLC SLLSGGLDSS SVAALAVGAL RDRGEDPLTC FSVGFSAAGS
310 320 330 340 350
GPGFVTGPRG GDDSAYAAEL ARHIGARHED LTLDAKLLSD PAARAAVLRA
360 370 380 390 400
RDLPQGLADM DTSLYLLFKA IRQRSTVALS GEGADELFGG YPWFHDENAV
410 420 430 440 450
RAETFPWMYM AGVAAAGGPA FLDPALPERL SLDAYRADRY AEAVAAVPVL
460 470 480 490 500
PGEAEEDRRM RKVGHLFLTR FLPMLLERKD RMSMAVGLEV RVPFLDHALV
510 520 530 540 550
EYVFNVPWSM KTFDGREKSL LRAAMAPELP DSVLTRKKEP YPTIADPAYD
560 570 580 590 600
QLLKGRLGAL MDDTGAPVRA LMDEKSAAEA YAAVRKASPE ELRFLRVGFE
610
SLLKINDWMR DYRVELAE
Length:618
Mass (Da):67,349
Last modified:May 5, 2009 - v1
Checksum:i150E6364432E2C1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ652572 Genomic DNA. Translation: ACN52309.1.
FJ436358 Genomic DNA. Translation: ACN80665.1.
AP017424 Genomic DNA. Translation: BAU84777.1.

Similar proteinsi

Entry informationi

Entry nameiC0JRY2_STRLU
AccessioniPrimary (citable) accession number: C0JRY2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: August 30, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)