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C0IR59

- C0IR59_BABDI

UniProt

C0IR59 - C0IR59_BABDI

Protein
Submitted name:

Apical membrane antigen 1

Gene
N/A
Organism
Babesia divergens
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 2 (01 May 2013)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi207 – 2071Calcium; via carbonyl oxygenImported
    Metal bindingi209 – 2091CalciumImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. pathogenesis Source: InterPro

    Keywords - Ligandi

    CalciumImported, Metal-bindingImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Apical membrane antigen 1Imported
    OrganismiBabesia divergensImported
    Taxonomic identifieri32595 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaBabesiidaeBabesia

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4APMX-ray2.30A93-517[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR003298. Apmem_Ag1.
    [Graphical view]
    PfamiPF02430. AMA-1. 1 hit.
    [Graphical view]
    PRINTSiPR01361. MEROZOITESA.
    SMARTiSM00815. AMA-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C0IR59-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEATTTAKTG IWKKYLTLVV PILCVVILSG EVVPTEAAFH IRENEPKRRT    50
    SRRDGGRSSR RQTTNSRLSA DDDDSDDGDD SDRPRGRQQS SKSTPKDIWG 100
    RYMAKFDLAK SHGSGIYVDL GGTERVGATQ HRMPTGKCPV MGKVINLGNN 150
    ADFLNRISAE NPQDRGLAFP DTAVAVTRNS NARNRAAAEK TEIILSPVSA 200
    ADLVRWGYDG NDVANCAEYA GNIIPASDTA TKYRYPCVYD AKEEMCHILF 250
    TPMQYNRGSR YCDNDGSQDE GTSSLLCMEP MKSGIDAHLY YGSSRVDKKW 300
    EENCPMYPVK DAIFGRGANG SCVAIESAFE EFTRDAEECS ALMFENAAAD 350
    LEIDEEADNF DELKTLSDGL RNIKASKIAQ ALFSPIAKAG TSAKNSKGVG 400
    MNWANYDSNT GLCRVIEETP NCLIIDAGSF AMTAVGSPLE QDAVPFPCDI 450
    VTNGYIEPRP RSRHRNTTPI FEVTTALSRE ALKCSKYVHE KYSESCGTYY 500
    YCSEEKPSSW AFWRNLDWKR VAKYVMSLIA IAILYMAIHW TYKRLWTTKA 550
    KPESDEYERF MSKYDYDEGI HTKGHMDQQL RSDAYVWGEA AARPSDVTPV 600
    HLSKVQ 606
    Length:606
    Mass (Da):67,556
    Last modified:May 1, 2013 - v2
    Checksum:iE49CB1D77C90F15D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU486539 mRNA. Translation: ACC96234.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU486539 mRNA. Translation: ACC96234.2 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4APM X-ray 2.30 A 93-517 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR003298. Apmem_Ag1.
    [Graphical view ]
    Pfami PF02430. AMA-1. 1 hit.
    [Graphical view ]
    PRINTSi PR01361. MEROZOITESA.
    SMARTi SM00815. AMA-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Babesia divergens apical membrane antigen 1 and its interaction with the human red blood cell."
      Montero E., Rodriguez M., Oksov Y., Lobo C.A.
      Infect. Immun. 77:4783-4793(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion."
      Tonkin M.L., Crawford J., Lebrun M.L., Boulanger M.J.
      Protein Sci. 22:114-127(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 93-517 IN COMPLEX WITH CALCIUM.
    3. Montero E., Lobo C.A.
      Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiC0IR59_BABDI
    AccessioniPrimary (citable) accession number: C0IR59
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 5, 2009
    Last sequence update: May 1, 2013
    Last modified: October 1, 2014
    This is version 11 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3