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C0IR59

- C0IR59_BABDI

UniProt

C0IR59 - C0IR59_BABDI

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Protein
Submitted name:

Apical membrane antigen 1

Gene
N/A
Organism
Babesia divergens
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi207 – 2071Calcium; via carbonyl oxygenImported
Metal bindingi209 – 2091CalciumImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumImported, Metal-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
Apical membrane antigen 1Imported
OrganismiBabesia divergensImported
Taxonomic identifieri32595 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaBabesiidaeBabesia

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4APMX-ray2.30A93-517[»]

Family & Domainsi

Family and domain databases

InterProiIPR003298. Apmem_Ag1.
[Graphical view]
PfamiPF02430. AMA-1. 1 hit.
[Graphical view]
PRINTSiPR01361. MEROZOITESA.
SMARTiSM00815. AMA-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0IR59-1 [UniParc]FASTAAdd to Basket

« Hide

MEATTTAKTG IWKKYLTLVV PILCVVILSG EVVPTEAAFH IRENEPKRRT    50
SRRDGGRSSR RQTTNSRLSA DDDDSDDGDD SDRPRGRQQS SKSTPKDIWG 100
RYMAKFDLAK SHGSGIYVDL GGTERVGATQ HRMPTGKCPV MGKVINLGNN 150
ADFLNRISAE NPQDRGLAFP DTAVAVTRNS NARNRAAAEK TEIILSPVSA 200
ADLVRWGYDG NDVANCAEYA GNIIPASDTA TKYRYPCVYD AKEEMCHILF 250
TPMQYNRGSR YCDNDGSQDE GTSSLLCMEP MKSGIDAHLY YGSSRVDKKW 300
EENCPMYPVK DAIFGRGANG SCVAIESAFE EFTRDAEECS ALMFENAAAD 350
LEIDEEADNF DELKTLSDGL RNIKASKIAQ ALFSPIAKAG TSAKNSKGVG 400
MNWANYDSNT GLCRVIEETP NCLIIDAGSF AMTAVGSPLE QDAVPFPCDI 450
VTNGYIEPRP RSRHRNTTPI FEVTTALSRE ALKCSKYVHE KYSESCGTYY 500
YCSEEKPSSW AFWRNLDWKR VAKYVMSLIA IAILYMAIHW TYKRLWTTKA 550
KPESDEYERF MSKYDYDEGI HTKGHMDQQL RSDAYVWGEA AARPSDVTPV 600
HLSKVQ 606
Length:606
Mass (Da):67,556
Last modified:May 1, 2013 - v2
Checksum:iE49CB1D77C90F15D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU486539 mRNA. Translation: ACC96234.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU486539 mRNA. Translation: ACC96234.2 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4APM X-ray 2.30 A 93-517 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR003298. Apmem_Ag1.
[Graphical view ]
Pfami PF02430. AMA-1. 1 hit.
[Graphical view ]
PRINTSi PR01361. MEROZOITESA.
SMARTi SM00815. AMA-1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Babesia divergens apical membrane antigen 1 and its interaction with the human red blood cell."
    Montero E., Rodriguez M., Oksov Y., Lobo C.A.
    Infect. Immun. 77:4783-4793(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion."
    Tonkin M.L., Crawford J., Lebrun M.L., Boulanger M.J.
    Protein Sci. 22:114-127(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 93-517 IN COMPLEX WITH CALCIUM.
  3. Montero E., Lobo C.A.
    Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC0IR59_BABDI
AccessioniPrimary (citable) accession number: C0IR59
Entry historyi
Integrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 1, 2013
Last modified: September 3, 2014
This is version 10 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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