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C0IR59

- C0IR59_BABDI

UniProt

C0IR59 - C0IR59_BABDI

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Protein
Submitted name:

Apical membrane antigen 1

Gene
N/A
Organism
Babesia divergens
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumImported, Metal-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
Apical membrane antigen 1Imported
OrganismiBabesia divergensImported
Taxonomic identifieri32595 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaBabesiidaeBabesia

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4APMX-ray2.30A93-517[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR003298. Apmem_Ag1.
[Graphical view]
PfamiPF02430. AMA-1. 1 hit.
[Graphical view]
PRINTSiPR01361. MEROZOITESA.
SMARTiSM00815. AMA-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0IR59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEATTTAKTG IWKKYLTLVV PILCVVILSG EVVPTEAAFH IRENEPKRRT
60 70 80 90 100
SRRDGGRSSR RQTTNSRLSA DDDDSDDGDD SDRPRGRQQS SKSTPKDIWG
110 120 130 140 150
RYMAKFDLAK SHGSGIYVDL GGTERVGATQ HRMPTGKCPV MGKVINLGNN
160 170 180 190 200
ADFLNRISAE NPQDRGLAFP DTAVAVTRNS NARNRAAAEK TEIILSPVSA
210 220 230 240 250
ADLVRWGYDG NDVANCAEYA GNIIPASDTA TKYRYPCVYD AKEEMCHILF
260 270 280 290 300
TPMQYNRGSR YCDNDGSQDE GTSSLLCMEP MKSGIDAHLY YGSSRVDKKW
310 320 330 340 350
EENCPMYPVK DAIFGRGANG SCVAIESAFE EFTRDAEECS ALMFENAAAD
360 370 380 390 400
LEIDEEADNF DELKTLSDGL RNIKASKIAQ ALFSPIAKAG TSAKNSKGVG
410 420 430 440 450
MNWANYDSNT GLCRVIEETP NCLIIDAGSF AMTAVGSPLE QDAVPFPCDI
460 470 480 490 500
VTNGYIEPRP RSRHRNTTPI FEVTTALSRE ALKCSKYVHE KYSESCGTYY
510 520 530 540 550
YCSEEKPSSW AFWRNLDWKR VAKYVMSLIA IAILYMAIHW TYKRLWTTKA
560 570 580 590 600
KPESDEYERF MSKYDYDEGI HTKGHMDQQL RSDAYVWGEA AARPSDVTPV

HLSKVQ
Length:606
Mass (Da):67,556
Last modified:May 1, 2013 - v2
Checksum:iE49CB1D77C90F15D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU486539 mRNA. Translation: ACC96234.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU486539 mRNA. Translation: ACC96234.2 .

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4APM X-ray 2.30 A 93-517 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR003298. Apmem_Ag1.
[Graphical view ]
Pfami PF02430. AMA-1. 1 hit.
[Graphical view ]
PRINTSi PR01361. MEROZOITESA.
SMARTi SM00815. AMA-1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Babesia divergens apical membrane antigen 1 and its interaction with the human red blood cell."
    Montero E., Rodriguez M., Oksov Y., Lobo C.A.
    Infect. Immun. 77:4783-4793(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion."
    Tonkin M.L., Crawford J., Lebrun M.L., Boulanger M.J.
    Protein Sci. 22:114-127(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 93-517 IN COMPLEX WITH CALCIUM, ACTIVE SITE.
  3. Montero E., Lobo C.A.
    Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC0IR59_BABDI
AccessioniPrimary (citable) accession number: C0IR59
Entry historyi
Integrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 1, 2013
Last modified: November 26, 2014
This is version 13 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3