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Protein
Submitted name:

DNA mismatch repair protein MSH2, putative

Gene

PF3D7_0706700

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-PFA-5358565. Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha).

Names & Taxonomyi

Protein namesi
Submitted name:
DNA mismatch repair protein MSH2, putativeImported
Gene namesi
ORF Names:PF3D7_0706700Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0706700.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

ProteinModelPortaliC0H4L8.
SMRiC0H4L8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini697 – 713DNA_MISMATCH_REPAIR_2InterPro annotationAdd BLAST17

Phylogenomic databases

InParanoidiC0H4L8.
KOiK08735.
OMAiKMEGGKM.
PhylomeDBiC0H4L8.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
InterProiView protein in InterPro
IPR011184. DNA_mismatch_repair_Msh2.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR036187. DNA_mismatch_repair_MutS_sf.
IPR032642. Msh2.
IPR036678. MutS_con_dom_sf.
IPR027417. P-loop_NTPase.
PANTHERiPTHR11361:SF35. PTHR11361:SF35. 1 hit.
PfamiView protein in Pfam
PF05192. MutS_III. 1 hit.
PF00488. MutS_V. 1 hit.
PIRSFiPIRSF005813. MSH2. 1 hit.
SMARTiView protein in SMART
SM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
SUPFAMiSSF48334. SSF48334. 3 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C0H4L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCTDECEDK SRVISFNLDV RNNIRYVGIC IYDIYSNEFS LCEYIENEHF
60 70 80 90 100
TVLESILLQT RPSSCLYLSH NEKIDEKRIN LILNLCDIKS KELPKIYYES
110 120 130 140 150
CSIENDLMKL LKGSDIKQCV HFLTDLQLAC KCLCSIVKHL DLLNDNGSIN
160 170 180 190 200
KCILKNYHIN KYLKLDKAAM VALNIYDDIH IDYGSNKNTT KINSSSANTL
210 220 230 240 250
TLYKFLNKCK TKIGQRKLLN WIIHPIRDEK KINERLDMVE IFKEESVIRS
260 270 280 290 300
IIQSDYLRKV CDLQIIIKKF KTTSSYLNDT KDNIKGSNNN DNIYDHNNNN
310 320 330 340 350
TMIMKKKNYN IIFKSKHSCN LEDLVKLYDT IVVSKKIYYL LNDYKGTNQD
360 370 380 390 400
TLNKKILKPL GECLIKLEPY LKLIELTIDF EEIEKQNNYL ISRTFDDDLD
410 420 430 440 450
LLATQKDNIY NLIKEHRLEV EEDIQYLKGK EKIKKKATTS KLIGGTINNS
460 470 480 490 500
NNNYNNNNIK EDIKLVECNI NIFLFRAVKK DINYIQERKN IYIQVRMNKN
510 520 530 540 550
EILFHTNKLK NLCRQYEHIL NQYNIAQESL AHKAIQVACS YWEPIIILSK
560 570 580 590 600
IISDIDIFCS FGFICCSSIS TYVRPEIEEN GHILHMKNSR HPLVESNLLL
610 620 630 640 650
INNFIPNDVY MNKDITRLNI ITGPNMGGKS TYIRQIALIC VMAHIGCFVP
660 670 680 690 700
CTYAKIPIFT QIMCRVGSSD IQLKGISTFF SEMIEIAAII KNADQNSLII
710 720 730 740 750
IDELGRGTST YEGFGISWSV AHYILNTIKC FCLFATHFHE MSNLEDEYKG
760 770 780 790 800
VINNHVGAKI DTEKKKISFL YEIKKGYADK SYGVYVAQIA QLPKSVIHKA
810 820 830 840 850
FQKSKELESV ENRHYFKKKL LTQTNQQNDT NHTSNYNKSI SYLKEIFNVT
860 870
HEQEFLTAFK KYKHELKNIF NEI
Length:873
Mass (Da):101,546
Last modified:May 5, 2009 - v1
Checksum:i8E7DBBC5DA027460
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844506 Genomic DNA. Translation: CAX64038.1.
RefSeqiXP_002808765.1. XM_002808719.1.

Genome annotation databases

EnsemblProtistsiCAX64038; CAX64038; PF3D7_0706700.
GeneDBiPF3D7_0706700.1:pep.
GeneIDi9221883.
KEGGipfa:MAL7P1.206.

Similar proteinsi

Entry informationi

Entry nameiC0H4L8_PLAF7
AccessioniPrimary (citable) accession number: C0H4L8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: October 25, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported