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Protein

Putative t-complex protein 10A homolog 2

Gene

TCP10L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Names & Taxonomyi

Protein namesi
Recommended name:
Putative t-complex protein 10A homolog 2
Alternative name(s):
T-complex 10-like protein 2
Gene namesi
Name:TCP10L2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:21254. TCP10L2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 353353Putative t-complex protein 10A homolog 2PRO_0000414121Add
BLAST

Proteomic databases

PaxDbiB9ZVM9.

Expressioni

Gene expression databases

BgeeiB9ZVM9.
ExpressionAtlasiB9ZVM9. baseline.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000355797.

Structurei

3D structure databases

ProteinModelPortaliB9ZVM9.
SMRiB9ZVM9. Positions 313-341.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili69 – 10537Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the TCP10 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG118246.
GeneTreeiENSGT00530000064597.
HOGENOMiHOG000136328.
InParanoidiB9ZVM9.
OMAiEEKRHPN.
PhylomeDBiB9ZVM9.

Family and domain databases

InterProiIPR026581. TCP10_fam.
[Graphical view]
PANTHERiPTHR10331. PTHR10331. 1 hit.

Sequencei

Sequence statusi: Complete.

B9ZVM9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLEGQLEARE PKEGTHPEDP CPGAGAAMEK TPAAAEVPRE DSNAGEMPSL
60 70 80 90 100
QQQITSLHQE LGRQQSLWAD IHRKLQSHMD ALRKQNRELR EELRGLQRQQ
110 120 130 140 150
WEAGKKPAAS PHAGRESHTL ALEPAFGKIS PLSADEETTP KYAGRKSQSA
160 170 180 190 200
TLLGQRWSSN HLAPPKPMSL KTERINSGKT PPQEDREKSP PGRRQDRSPA
210 220 230 240 250
PTGRPTPGAE RREVSEDGKI MHPSSRSLQN SGGRKSPVQA SQAATLQEQT
260 270 280 290 300
AAAGVADRSS SVLGSSEGGF LSRVQAEEFA SSSPDSAERQ NLPVNPPSSL
310 320 330 340 350
EIAQAMDTKM KKEEVQEEKR HPNGKADDCR RSGFPSEFPG ALHAAPSRQD

MGP
Length:353
Mass (Da):38,357
Last modified:November 3, 2009 - v2
Checksum:i00AB5B2876E604E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121935 Genomic DNA. No translation available.
CCDSiCCDS47514.1.
RefSeqiNP_001138593.1. NM_001145121.1.
UniGeneiHs.691976.

Genome annotation databases

EnsembliENST00000366832; ENSP00000355797; ENSG00000166984.
GeneIDi401285.
KEGGihsa:401285.
UCSCiuc010kkp.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121935 Genomic DNA. No translation available.
CCDSiCCDS47514.1.
RefSeqiNP_001138593.1. NM_001145121.1.
UniGeneiHs.691976.

3D structure databases

ProteinModelPortaliB9ZVM9.
SMRiB9ZVM9. Positions 313-341.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000355797.

Proteomic databases

PaxDbiB9ZVM9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000366832; ENSP00000355797; ENSG00000166984.
GeneIDi401285.
KEGGihsa:401285.
UCSCiuc010kkp.3. human.

Organism-specific databases

CTDi401285.
GeneCardsiGC06P167559.
HGNCiHGNC:21254. TCP10L2.
neXtProtiNX_B9ZVM9.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG118246.
GeneTreeiENSGT00530000064597.
HOGENOMiHOG000136328.
InParanoidiB9ZVM9.
OMAiEEKRHPN.
PhylomeDBiB9ZVM9.

Miscellaneous databases

GenomeRNAii401285.
NextBioi106692.

Gene expression databases

BgeeiB9ZVM9.
ExpressionAtlasiB9ZVM9. baseline.

Family and domain databases

InterProiIPR026581. TCP10_fam.
[Graphical view]
PANTHERiPTHR10331. PTHR10331. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiTCP2L_HUMAN
AccessioniPrimary (citable) accession number: B9ZVM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: November 3, 2009
Last modified: January 7, 2015
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.