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B9ZVM9 (TCP2L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative t-complex protein 10A homolog 2
Alternative name(s):
T-complex 10-like protein 2
Gene names
Name:TCP10L2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length353 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Sequence similarities

Belongs to the TCP10 family.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   DomainCoiled coil
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 353353Putative t-complex protein 10A homolog 2
PRO_0000414121

Regions

Coiled coil69 – 10537 Potential

Sequences

Sequence LengthMass (Da)Tools
B9ZVM9 [UniParc].

Last modified November 3, 2009. Version 2.
Checksum: 00AB5B2876E604E1

FASTA35338,357
        10         20         30         40         50         60 
MLEGQLEARE PKEGTHPEDP CPGAGAAMEK TPAAAEVPRE DSNAGEMPSL QQQITSLHQE 

        70         80         90        100        110        120 
LGRQQSLWAD IHRKLQSHMD ALRKQNRELR EELRGLQRQQ WEAGKKPAAS PHAGRESHTL 

       130        140        150        160        170        180 
ALEPAFGKIS PLSADEETTP KYAGRKSQSA TLLGQRWSSN HLAPPKPMSL KTERINSGKT 

       190        200        210        220        230        240 
PPQEDREKSP PGRRQDRSPA PTGRPTPGAE RREVSEDGKI MHPSSRSLQN SGGRKSPVQA 

       250        260        270        280        290        300 
SQAATLQEQT AAAGVADRSS SVLGSSEGGF LSRVQAEEFA SSSPDSAERQ NLPVNPPSSL 

       310        320        330        340        350 
EIAQAMDTKM KKEEVQEEKR HPNGKADDCR RSGFPSEFPG ALHAAPSRQD MGP 

« Hide

References

[1]"The DNA sequence and analysis of human chromosome 6."
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL121935 Genomic DNA. No translation available.
RefSeqNP_001138593.1. NM_001145121.1.
UniGeneHs.691976.

3D structure databases

ProteinModelPortalB9ZVM9.
SMRB9ZVM9. Positions 313-341.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000355797.

Proteomic databases

PaxDbB9ZVM9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000366832; ENSP00000355797; ENSG00000166984.
GeneID401285.
KEGGhsa:401285.
UCSCuc010kkp.3. human.

Organism-specific databases

CTD401285.
GeneCardsGC06P167559.
HGNCHGNC:21254. TCP10L2.
neXtProtNX_B9ZVM9.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG118246.
HOGENOMHOG000136328.
OMAEEKRHPN.
PhylomeDBB9ZVM9.

Gene expression databases

BgeeB9ZVM9.

Family and domain databases

InterProIPR026581. TCP10_fam.
[Graphical view]
PANTHERPTHR10331. PTHR10331. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi401285.
NextBio106692.

Entry information

Entry nameTCP2L_HUMAN
AccessionPrimary (citable) accession number: B9ZVM9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: November 3, 2009
Last modified: April 16, 2014
This is version 40 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 6

Human chromosome 6: entries, gene names and cross-references to MIM