B9ZVM9 (TCP2L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative t-complex protein 10A homolog 2

Alternative name(s):
T-complex 10-like protein 2

Gene names

Name:

TCP10L2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	353 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Sequence similarities	Belongs to the TCP10 family.
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 353	353	Putative t-complex protein 10A homolog 2		PRO_0000414121
Regions
	Coiled coil	69 – 105	37	Potential

Sequences

	Sequence		Length	Mass (Da)
	B9ZVM9 [UniParc]. Last modified November 3, 2009. Version 2. Checksum: 00AB5B2876E604E1	FASTA	353	38,357
	10 20 30 40 50 60 MLEGQLEARE PKEGTHPEDP CPGAGAAMEK TPAAAEVPRE DSNAGEMPSL QQQITSLHQE 70 80 90 100 110 120 LGRQQSLWAD IHRKLQSHMD ALRKQNRELR EELRGLQRQQ WEAGKKPAAS PHAGRESHTL 130 140 150 160 170 180 ALEPAFGKIS PLSADEETTP KYAGRKSQSA TLLGQRWSSN HLAPPKPMSL KTERINSGKT 190 200 210 220 230 240 PPQEDREKSP PGRRQDRSPA PTGRPTPGAE RREVSEDGKI MHPSSRSLQN SGGRKSPVQA 250 260 270 280 290 300 SQAATLQEQT AAAGVADRSS SVLGSSEGGF LSRVQAEEFA SSSPDSAERQ NLPVNPPSSL 310 320 330 340 350 EIAQAMDTKM KKEEVQEEKR HPNGKADDCR RSGFPSEFPG ALHAAPSRQD MGP

References

[1]

"The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S. Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL121935 Genomic DNA. No translation available.
IPI	IPI00873524.
RefSeq	NP_001138593.1. NM_001145121.1.
UniGene	Hs.691976.
3D structure databases
ProteinModelPortal	B9ZVM9.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000355797.
Proteomic databases
PaxDb	B9ZVM9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000366832; ENSP00000355797; ENSG00000166984.
GeneID	401285.
KEGG	hsa:401285.
UCSC	uc010kkp.3. human.
Organism-specific databases
CTD	401285.
GeneCards	GC06P167559.
HGNC	HGNC:21254. TCP10L2.
neXtProt	NX_B9ZVM9.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG118246.
HOGENOM	HOG000136328.
OMA	NGKADDC.
OrthoDB	EOG498V1J.
Gene expression databases
ArrayExpress	B9ZVM9.
Bgee	B9ZVM9.
Family and domain databases
InterPro	IPR026581. TCP10_fam. [Graphical view]
PANTHER	PTHR10331. PTHR10331. 1 hit.
ProtoNet	Search...
Other
GenomeRNAi	401285.
NextBio	106692.

Entry information

Entry name

TCP2L_HUMAN

Accession

Primary (citable) accession number: B9ZVM9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 14, 2011
Last sequence update:	November 3, 2009
Last modified:	April 3, 2013
This is version 35 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.