ID   B9X0J5_SALSA            Unreviewed;       118 AA.
AC   B9X0J5;
DT   14-APR-2009, integrated into UniProtKB/TrEMBL.
DT   14-APR-2009, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Cocaine- and amphetamine-regulated transcript precursor {ECO:0000313|RefSeq:NP_001140152.1};
DE   SubName: Full=Cocaine- and amphetamine-regulated transcript protein-like {ECO:0000313|RefSeq:XP_014031924.1, ECO:0000313|RefSeq:XP_014039313.1};
DE   SubName: Full=Cocaine-and amphetamine-regulated transcript {ECO:0000313|EMBL:BAH24100.1};
GN   Name=CART {ECO:0000313|EMBL:BAH24100.1};
GN   Synonyms=cart {ECO:0000313|RefSeq:NP_001140152.1}, LOC106587806
GN   {ECO:0000313|RefSeq:XP_014031924.1}, LOC106592486
GN   {ECO:0000313|RefSeq:XP_014039313.1}, LOC106597405
GN   {ECO:0000313|RefSeq:XP_014044074.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|EMBL:BAH24100.1};
RN   [1] {ECO:0000313|EMBL:BAH24100.1, ECO:0000313|RefSeq:NP_001140152.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Brain {ECO:0000313|EMBL:BAH24100.1};
RX   PubMed=19332070; DOI=10.1016/j.ygcen.2009.03.015;
RA   Murashita K., Kurokawa T., Ebbesson L.O., Stefansson S.O., Ronnestad I.;
RT   "Characterization, tissue distribution, and regulation of agouti-related
RT   protein (AgRP), cocaine- and amphetamine-regulated transcript (CART) and
RT   neuropeptide Y (NPY) in Atlantic salmon (Salmo salar).";
RL   Gen. Comp. Endocrinol. 162:160-171(2009).
RN   [2] {ECO:0000313|RefSeq:NP_001140152.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25846408;
RA   Volkoff H.;
RT   "Cloning and tissue distribution of appetite-regulating peptides in
RT   pirapitinga (Piaractus brachypomus).";
RL   J Anim Physiol Anim Nutr (Berl) 99:987-1001(2015).
RN   [3] {ECO:0000313|RefSeq:NP_001140152.1, ECO:0000313|RefSeq:XP_014031924.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014031924.1,
RC   ECO:0000313|RefSeq:XP_014039313.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the CART family.
CC       {ECO:0000256|ARBA:ARBA00005294}.
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DR   EMBL; AB455538; BAH24100.1; -; mRNA.
DR   RefSeq; NP_001140152.1; NM_001146680.1.
DR   RefSeq; XP_014031924.1; XM_014176449.1.
DR   RefSeq; XP_014039313.1; XM_014183838.1.
DR   RefSeq; XP_014044074.1; XM_014188599.1.
DR   STRING; 8030.ENSSSAP00000024659; -.
DR   PaxDb; 8030-ENSSSAP00000024659; -.
DR   Ensembl; ENSSSAT00000034744; ENSSSAP00000024659; ENSSSAG00000020479.
DR   GeneID; 100286783; -.
DR   GeneID; 106587806; -.
DR   KEGG; sasa:100286783; -.
DR   KEGG; sasa:106587806; -.
DR   KEGG; sasa:106592486; -.
DR   KEGG; sasa:106597405; -.
DR   CTD; 35334; -.
DR   OMA; ETNDSDM; -.
DR   OrthoDB; 3971848at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa26.
DR   Bgee; ENSSSAG00000008908; Expressed in camera-type eye.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR   GO; GO:0008343; P:adult feeding behavior; IEA:InterPro.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:InterPro.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0032099; P:negative regulation of appetite; IEA:InterPro.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:InterPro.
DR   CDD; cd22741; CART_CTD-like; 1.
DR   Gene3D; 4.10.40.30; CART, C-terminal domain; 1.
DR   InterPro; IPR009106; CART.
DR   InterPro; IPR036722; CART_C_sf.
DR   PANTHER; PTHR16655; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN; 1.
DR   PANTHER; PTHR16655:SF5; COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT 2-RELATED; 1.
DR   Pfam; PF06373; CART; 1.
DR   SUPFAM; SSF64546; Satiety factor CART (cocaine and amphetamine regulated transcript); 1.
PE   2: Evidence at transcript level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001140152.1}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..118
FT                   /evidence="ECO:0000256|SAM:SignalP,
FT                   ECO:0000313|RefSeq:NP_001140152.1"
FT                   /id="PRO_5009732340"
SQ   SEQUENCE   118 AA;  13357 MW;  F7DDBA9BA9A651E5 CRC64;
     MESSRLWTRA VVCAVLLSIV LSAEIDYSDS ELDLDTRSVR DFYPKDPNLT NEKQLLGALH
     DVLKKLQTKR LPFWEKKFGQ VPTCDVGEQC AVRKGARIGK MCDCPRGAFC NSYLLKCL
//