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B9X0J1

- STBOS_STERE

UniProt

B9X0J1 - STBOS_STERE

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Protein

Baccharis oxide synthase

Gene
N/A
Organism
Stevia rebaudiana (Stevia) (Eupatorium rebaudianum)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Oxidosqualene cyclase converting (3S)-2,3-epoxy-2,3-dihydrosqualene to baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring. Also mediates conversion of other triterpenoids at a much lower level.1 Publication

Catalytic activityi

(3S)-2,3-epoxy-2,3-dihydrosqualene = baccharis oxide.1 Publication

GO - Molecular functioni

  1. oxidosqualene cyclase activity Source: UniProtKB

GO - Biological processi

  1. metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Baccharis oxide synthase (EC:5.4.99.51)
Short name:
StrBOS
OrganismiStevia rebaudiana (Stevia) (Eupatorium rebaudianum)
Taxonomic identifieri55670 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceEupatorieaeStevia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 761761Baccharis oxide synthasePRO_0000418758Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati148 – 18942PFTB 1Add
BLAST
Repeati639 – 68042PFTB 2Add
BLAST

Sequence similaritiesi

Contains 2 PFTB repeats.

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.50.10.20. 2 hits.
InterProiIPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR002365. Terpene_synthase_CS.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamiPF00432. Prenyltrans. 1 hit.
[Graphical view]
SUPFAMiSSF48239. SSF48239. 2 hits.
TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.
PROSITEiPS01074. TERPENE_SYNTHASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9X0J1-1 [UniParc]FASTAAdd to Basket

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MWRLKIADGN NNPYLYSTNN FVGRQTWEFD PNYGTQEERD EVEQARQHFW    50
NNRHQFKATG DVLWRMQFIR EKRFKQTIPQ VKIEDGEEIS YDKVTATLRR 100
SVHLLAALQA DDGHWPAENT GPMFFIQPLV ICLYITGHLD RVFPKEHKKE 150
ILRYLYTQQN EDGGWGLHIE GQSIMFGTIM SYVCMRLLGE GPDGGLNGAC 200
TKARKWILDH GSVLASPSWG KIYLTILGVH EWEGCNPLPP EFWILPSIFP 250
MHPAKMWCYC RLIYMPMSYL YGRRFVGPIT PLVLQLREEL YSQSYNDIKW 300
KSTRHLVVKE DLHYPHPWLQ DLMWDGLYIF TEPLLTRWPF SKLREKALKT 350
TINHIHYEDE NSRYITIGAV EKSLCMLACW DEDPDGVCFK KHLARIPDYI 400
WVSEDGLKMQ SFGSQLWDAS LAIQALLATD LNHDIEPILR KGHDFIKASQ 450
VKDNPSGDFK SMYRHITKGS WTFSDQDHGW QTSDCTTEGL KCCLLLSKMS 500
AEIVGEKMQP EQFYDAVNLI LSLQCKNGGE AGWEPAGESN WLEFLNPSEL 550
FEDIVLEHDS VECTATGMQA LVIFKKLYPK HRREEIEKFL KDACGYLEKV 600
QMQDGSWYGE WGICFTYGTC FALGGMEAIG KTYENCEAIR RAVNFLLTTQ 650
RNDGGWGESY RSSPKKKYVP LEGNRSNLVQ TACALMGLIR SKQEERDPTP 700
LHRAAKLLIN SQMENGDFPQ EETGGVFKKN CLLHYPMYRN IYTLWALGEY 750
RKKVLPQPTK V 761
Length:761
Mass (Da):88,050
Last modified:April 14, 2009 - v1
Checksum:i79354A8BA097B2C2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB455264 mRNA. Translation: BAH23676.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB455264 mRNA. Translation: BAH23676.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.50.10.20. 2 hits.
InterProi IPR001330. Prenyltrans.
IPR018333. Squalene_cyclase.
IPR002365. Terpene_synthase_CS.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view ]
Pfami PF00432. Prenyltrans. 1 hit.
[Graphical view ]
SUPFAMi SSF48239. SSF48239. 2 hits.
TIGRFAMsi TIGR01787. squalene_cyclas. 1 hit.
PROSITEi PS01074. TERPENE_SYNTHASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Biosynthesis of baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring."
    Shibuya M., Sagara A., Saitoh A., Kushiro T., Ebizuka Y.
    Org. Lett. 10:5071-5074(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY.
    Tissue: Root.

Entry informationi

Entry nameiSTBOS_STERE
AccessioniPrimary (citable) accession number: B9X0J1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: April 14, 2009
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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