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B9X0J1

- STBOS_STERE

UniProt

B9X0J1 - STBOS_STERE

Protein

Baccharis oxide synthase

Gene
N/A
Organism
Stevia rebaudiana (Stevia) (Eupatorium rebaudianum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (14 Apr 2009)
      Previous versions | rss
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    Functioni

    Oxidosqualene cyclase converting (3S)-2,3-epoxy-2,3-dihydrosqualene to baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring. Also mediates conversion of other triterpenoids at a much lower level.1 Publication

    Catalytic activityi

    (3S)-2,3-epoxy-2,3-dihydrosqualene = baccharis oxide.1 Publication

    GO - Molecular functioni

    1. oxidosqualene cyclase activity Source: UniProtKB

    GO - Biological processi

    1. metabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Isomerase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Baccharis oxide synthase (EC:5.4.99.51)
    Short name:
    StrBOS
    OrganismiStevia rebaudiana (Stevia) (Eupatorium rebaudianum)
    Taxonomic identifieri55670 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceEupatorieaeStevia

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 761761Baccharis oxide synthasePRO_0000418758Add
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati148 – 18942PFTB 1Add
    BLAST
    Repeati639 – 68042PFTB 2Add
    BLAST

    Sequence similaritiesi

    Belongs to the terpene cyclase/mutase family.Curated
    Contains 2 PFTB repeats.Curated

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.50.10.20. 2 hits.
    InterProiIPR001330. Prenyltrans.
    IPR018333. Squalene_cyclase.
    IPR002365. Terpene_synthase_CS.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view]
    PfamiPF00432. Prenyltrans. 1 hit.
    [Graphical view]
    SUPFAMiSSF48239. SSF48239. 2 hits.
    TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.
    PROSITEiPS01074. TERPENE_SYNTHASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B9X0J1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWRLKIADGN NNPYLYSTNN FVGRQTWEFD PNYGTQEERD EVEQARQHFW    50
    NNRHQFKATG DVLWRMQFIR EKRFKQTIPQ VKIEDGEEIS YDKVTATLRR 100
    SVHLLAALQA DDGHWPAENT GPMFFIQPLV ICLYITGHLD RVFPKEHKKE 150
    ILRYLYTQQN EDGGWGLHIE GQSIMFGTIM SYVCMRLLGE GPDGGLNGAC 200
    TKARKWILDH GSVLASPSWG KIYLTILGVH EWEGCNPLPP EFWILPSIFP 250
    MHPAKMWCYC RLIYMPMSYL YGRRFVGPIT PLVLQLREEL YSQSYNDIKW 300
    KSTRHLVVKE DLHYPHPWLQ DLMWDGLYIF TEPLLTRWPF SKLREKALKT 350
    TINHIHYEDE NSRYITIGAV EKSLCMLACW DEDPDGVCFK KHLARIPDYI 400
    WVSEDGLKMQ SFGSQLWDAS LAIQALLATD LNHDIEPILR KGHDFIKASQ 450
    VKDNPSGDFK SMYRHITKGS WTFSDQDHGW QTSDCTTEGL KCCLLLSKMS 500
    AEIVGEKMQP EQFYDAVNLI LSLQCKNGGE AGWEPAGESN WLEFLNPSEL 550
    FEDIVLEHDS VECTATGMQA LVIFKKLYPK HRREEIEKFL KDACGYLEKV 600
    QMQDGSWYGE WGICFTYGTC FALGGMEAIG KTYENCEAIR RAVNFLLTTQ 650
    RNDGGWGESY RSSPKKKYVP LEGNRSNLVQ TACALMGLIR SKQEERDPTP 700
    LHRAAKLLIN SQMENGDFPQ EETGGVFKKN CLLHYPMYRN IYTLWALGEY 750
    RKKVLPQPTK V 761
    Length:761
    Mass (Da):88,050
    Last modified:April 14, 2009 - v1
    Checksum:i79354A8BA097B2C2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB455264 mRNA. Translation: BAH23676.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB455264 mRNA. Translation: BAH23676.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.50.10.20. 2 hits.
    InterProi IPR001330. Prenyltrans.
    IPR018333. Squalene_cyclase.
    IPR002365. Terpene_synthase_CS.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view ]
    Pfami PF00432. Prenyltrans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48239. SSF48239. 2 hits.
    TIGRFAMsi TIGR01787. squalene_cyclas. 1 hit.
    PROSITEi PS01074. TERPENE_SYNTHASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Biosynthesis of baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring."
      Shibuya M., Sagara A., Saitoh A., Kushiro T., Ebizuka Y.
      Org. Lett. 10:5071-5074(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, CATALYTIC ACTIVITY.
      Tissue: Root.

    Entry informationi

    Entry nameiSTBOS_STERE
    AccessioniPrimary (citable) accession number: B9X0J1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2012
    Last sequence update: April 14, 2009
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3