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Protein

Glutamate decarboxylase

Gene

CD36_10760

Organism
Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:CD36_10760Imported
OrganismiCandida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast)Imported
Taxonomic identifieri573826 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000002605 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi573826.CD36_10760.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

B9W9E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLSKHIDAL RLETQILKKT PQAQLRKDQF IDAFDSHKNI PQFEIPQNSS
60 70 80 90 100
NEQLIYKYLS QELSLDGVPT LNLASFVNTY VDGTSLKLIE DNLTKNLADN
110 120 130 140 150
DEYPSLIDIQ TRCISILSNL WGAPGKVDNV TGNRVTNSIG TATTGSSEAI
160 170 180 190 200
MLAGLALKKR WQLKRKAEGK STANPNILMA TCAQVALEKF ACYFDVENRL
210 220 230 240 250
IPVTEESGHL IDVSKIKENI DENTIGIFVI MGSTFTGAFE PVEEISKLLD
260 270 280 290 300
EVEKERGLDI RIHVDGASGG FVAPFIFPHL KWDFAVSRVD SINTSGHKFG
310 320 330 340 350
LTSVGLGWVI WKDADLLPKE LRFSLDYLGG VEETFGLNFS RPGFPVITQY
360 370 380 390 400
YNFLTLGRQG YAKIFDGCMT NARLLSEFLE ESKYFEVVSV IHHKLSESER
410 420 430 440 450
KAQFTREVDD KHLDSKLYTI NEDFKPGLPV VAFRFSKEFR DKYPELPQEL
460 470 480 490 500
LSTLLRKRGY IIPNYHLPPS ENDKEILRVV VRNSLSLNLL ERLIQDITDA
510 520 530 540 550
TELLIKAADS ITDYVSTSGE HTDVENRERI HKLLAAIASG GVSEAKEEKH
560
KKDNHKSGKN KKSYRGTC
Length:568
Mass (Da):63,899
Last modified:March 24, 2009 - v1
Checksum:i278D6692DEF9C8C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM992688 Genomic DNA. Translation: CAX45430.1.
RefSeqiXP_002417718.1. XM_002417673.1.

Genome annotation databases

GeneIDi8045266.
KEGGicdu:CD36_10760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM992688 Genomic DNA. Translation: CAX45430.1.
RefSeqiXP_002417718.1. XM_002417673.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi573826.CD36_10760.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8045266.
KEGGicdu:CD36_10760.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841Imported.

Entry informationi

Entry nameiB9W9E8_CANDC
AccessioniPrimary (citable) accession number: B9W9E8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: February 4, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.