B9W0A9 (B9W0A9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mitochondrial protein lysine deacetylase EMBL ACM68947.1

Gene names

Name:

Sirt3 EMBL ACM68947.1 MGI 1927665

Organism

Mus musculus (Mouse) EMBL ACM68947.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	protein deacetylation Inferred from electronic annotation. Source: InterPro
Cellular_component	membrane Inferred from direct assay PubMed 11056054. Source: MGI mitochondrion Inferred from direct assay PubMed 18614015PubMed 19241369. Source: MGI
Molecular_function	NAD+ binding Inferred from electronic annotation. Source: InterPro NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from direct assay PubMed 19241369. Source: MGI hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B9W0A9 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: D8C936A83C4A8AF7	FASTA	334	36,615
	10 20 30 40 50 60 MALDPLGAVV LQSIMALSGR LALAALRLWG PGGGRRPISL CVGASGGFGG GGSSEKKFSL 70 80 90 100 110 120 QDVAELLRTR ACSRVVVMVG AGISTPSGIP DFRSPGSGLY SNLQQYDIPY PEAIFELGFF 130 140 150 160 170 180 FHNPKPFFML AKELYPGHYR PNVTHYFLRL LHDKELLLRL YTQNIDGLER ASGIPASKLV 190 200 210 220 230 240 EAHGTFVTAT CTVCRRSFPG EDIWADVMAD RVPRCPVCTG VVKPDIVFFG EQLPARFLLH 250 260 270 280 290 300 MADFALADLL LILGTSLEVE PFASLSEAVQ KSVPRLLINR DLVGPFVLSP RRKDVVQLGD 310 320 330 VVHGVERLVD LLGWTQELLD LMQRERGKLD GQDR

References

[1]	"A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein." Cooper H.M., Huang J.Y., Verdin E., Spelbrink J.N. PLoS ONE 4:E4986-E4986(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NIH Swiss EMBL ACM68947.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FJ621493 mRNA. Translation: ACM68947.1.
IPI	IPI00968349.
RefSeq	NP_001171275.1. NM_001177804.1.
UniGene	Mm.244216.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B9W0A9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	64384.
KEGG	mmu:64384.
UCSC	uc012fwl.1. mouse.
Organism-specific databases
CTD	23410.
MGI	MGI:1927665. Sirt3.
Phylogenomic databases
HOGENOM	HOG000085952.
HOVERGEN	HBG057095.
KO	K11413.
Gene expression databases
ArrayExpress	B9W0A9.
Bgee	B9W0A9.
Genevestigator	B9W0A9.
Family and domain databases
Gene3D	3.30.1600.10. 2 hits.
InterPro	IPR017328. NAD-dep_deAcase_SIR2_class_I. IPR003000. Sirtuin. IPR026591. Sirtuin_cat_small_dom. IPR026590. Ssirtuin_cat_dom. [Graphical view]
PANTHER	PTHR11085. PTHR11085. 1 hit.
Pfam	PF02146. SIR2. 1 hit. [Graphical view]
PIRSF	PIRSF037938. SIR2_euk. 1 hit.
PROSITE	PS50305. SIRTUIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SIRT3. mouse.
NextBio	320063.
SOURCE	Search...

Entry information

Entry name

B9W0A9_MOUSE

Accession

Primary (citable) accession number: B9W0A9

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	April 3, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)