Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

HNF4alpha10/11/12

Gene

HNF4A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi32 – 103Nuclear receptorPROSITE-ProRule annotationAdd BLAST72

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
HNF4alpha10/11/12Imported
Submitted name:
Hepatocyte nuclear factor 4-alphaImported
Gene namesi
Name:HNF4AImported
Synonyms:HNF4alphaImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000101076.16
HGNCiHGNC:5024 HNF4A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101076

PTM / Processingi

Proteomic databases

PeptideAtlasiB9VVT8

Expressioni

Gene expression databases

BgeeiENSG00000101076

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 103Nuclear receptorInterPro annotationAdd BLAST72

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4215 Eukaryota
ENOG410XQT8 LUCA
GeneTreeiENSGT00760000118948
HOVERGENiHBG082808

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00399 ZnF_C4, 1 hit
PROSITEiView protein in PROSITE
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Fragment.

B9VVT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDWGQGFPQ DPPDTSPSEG TNLNAPNSLG VSALCAICGD RATGKHYGAS
60 70 80 90 100
SCDGCKGFFR RSVRKNHMYS CRFSRQCVVD KDKRNQCRYC RLKKCFRAGM

KKE
Length:103
Mass (Da):11,507
Last modified:March 24, 2009 - v1
Checksum:iDEC3966F09802721
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei103Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117382 Genomic DNA No translation available.
AL132772 Genomic DNA No translation available.
FJ608822 mRNA Translation: ACM50922.1
RefSeqiNP_001274111.1, NM_001287182.1
NP_001274112.1, NM_001287183.1
NP_001274113.1, NM_001287184.1
UniGeneiHs.116462

Genome annotation databases

EnsembliENST00000609262; ENSP00000476310; ENSG00000101076
GeneIDi3172
UCSCiuc061xet.1 human

Similar proteinsi

Entry informationi

Entry nameiB9VVT8_HUMAN
AccessioniPrimary (citable) accession number: B9VVT8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: April 25, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health