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Protein
Submitted name:

HNF4alpha10/11/12

Gene

HNF4alpha

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
HNF4alpha10/11/12Imported
Submitted name:
Hepatocyte nuclear factor 4-alphaImported
Gene namesi
Name:HNF4alphaImported
Synonyms:HNF4AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:5024. HNF4A.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiB9VVT8.

Expressioni

Gene expression databases

BgeeiENSG00000101076.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000312987.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 10372Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG4215. Eukaryota.
ENOG410XQT8. LUCA.
GeneTreeiENSGT00760000118948.
HOVERGENiHBG082808.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiIPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00399. ZnF_C4. 1 hit.
[Graphical view]
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B9VVT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDWGQGFPQ DPPDTSPSEG TNLNAPNSLG VSALCAICGD RATGKHYGAS
60 70 80 90 100
SCDGCKGFFR RSVRKNHMYS CRFSRQCVVD KDKRNQCRYC RLKKCFRAGM

KKE
Length:103
Mass (Da):11,507
Last modified:March 24, 2009 - v1
Checksum:iDEC3966F09802721
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei103 – 1031Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117382 Genomic DNA. No translation available.
AL132772 Genomic DNA. No translation available.
FJ608822 mRNA. Translation: ACM50922.1.
RefSeqiNP_001274111.1. NM_001287182.1.
NP_001274112.1. NM_001287183.1.
NP_001274113.1. NM_001287184.1.
UniGeneiHs.116462.

Genome annotation databases

EnsembliENST00000609262; ENSP00000476310; ENSG00000101076.
GeneIDi3172.
UCSCiuc061xet.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117382 Genomic DNA. No translation available.
AL132772 Genomic DNA. No translation available.
FJ608822 mRNA. Translation: ACM50922.1.
RefSeqiNP_001274111.1. NM_001287182.1.
NP_001274112.1. NM_001287183.1.
NP_001274113.1. NM_001287184.1.
UniGeneiHs.116462.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000312987.

Proteomic databases

PeptideAtlasiB9VVT8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000609262; ENSP00000476310; ENSG00000101076.
GeneIDi3172.
UCSCiuc061xet.1. human.

Organism-specific databases

CTDi3172.
HGNCiHGNC:5024. HNF4A.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4215. Eukaryota.
ENOG410XQT8. LUCA.
GeneTreeiENSGT00760000118948.
HOVERGENiHBG082808.

Miscellaneous databases

GenomeRNAii3172.

Gene expression databases

BgeeiENSG00000101076.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiIPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00399. ZnF_C4. 1 hit.
[Graphical view]
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB9VVT8_HUMAN
AccessioniPrimary (citable) accession number: B9VVT8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.