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Protein

DNA ligase

Gene

RCOM_0474620

Organism
Ricinus communis (Castor bean)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:RCOM_0474620Imported
OrganismiRicinus communis (Castor bean)Imported
Taxonomic identifieri3988 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeAcalyphoideaeAcalypheaeRicinus
ProteomesiUP000008311 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiB9SCJ7.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9SCJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPRSAFDV LMKKSAANKK SQSSSPKKRK SPDSQIAPKT LINSTQSLQQ
60 70 80 90 100
QPPNTIQHKE TPQKPQDSSL SLGEEKKVDT AKKQRLAIAE MKGKIKSLMK
110 120 130 140 150
NPKDFDPNEV VYWEKGENVP FIFVCSAFEY LEDEKEKGRG NITNVACNML
160 170 180 190 200
RSVMSTTPDD LLALVYLLAN RVAPAHEGVE LGIGEAMIIK ALAEAFGRTE
210 220 230 240 250
KQVKKEYEGT GDLGRVAQAS RSSQSMMRRP EPLTVSKVFN TFQLIAKDSG
260 270 280 290 300
KDSQDKKKNR IKALLVAATD CEPQYLIRLL QGKLRINLAG QTLLAALGQA
310 320 330 340 350
AVFSENHCTV PSNIQSPLDE AAKIVKQVYS VLPVYDRIVP ALLNDGVWNL
360 370 380 390 400
PKTCSFTPGV PVGPMLAKPA KSVTEIVEKF QGKFTCEYKY DGERAQIHFL
410 420 430 440 450
ENGSVEIYSR NAERNTGKYP DVVVAISRSK KSSVKSFVLD CEIVAYNRGE
460 470 480 490 500
KKILPFQILS TRPRKNVVMS DIKVDVCIYA FDMLYLNGKP LIEEQLEDRR
510 520 530 540 550
KLLYDSFEED PEHFQFATAI TSNDLEEIQK FLDAAVDASC EGLIIKTLDK
560 570 580 590 600
DATYEPSKRS NNWVKLKKDY IESIGDSLDL VPIAAYHGRG KRTGVYGAFL
610 620 630 640 650
LACYNSSTEE FESICKIGTG FSEQVLEERS NSLRAKVVPQ PKSYYRYEEK
660 670 680 690 700
IKPDVWFEPT EVWEVKAADL TISPVHRAAV GIVNSDKGIS LRFPRLMRVR
710 720 730
EDKSPEEATS SDQVADMYNA QKQNQPKVTQ ADSDDDQ
Length:737
Mass (Da):82,467
Last modified:March 23, 2009 - v1
Checksum:iD245BEFD7356ECD1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973922 Genomic DNA. Translation: EEF38656.1.
RefSeqiXP_002523716.1. XM_002523670.1.

Genome annotation databases

GeneIDi8275235.
KEGGircu:RCOM_0474620.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973922 Genomic DNA. Translation: EEF38656.1.
RefSeqiXP_002523716.1. XM_002523670.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8275235.
KEGGircu:RCOM_0474620.

Phylogenomic databases

InParanoidiB9SCJ7.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. HaleImported.

Entry informationi

Entry nameiB9SCJ7_RICCO
AccessioniPrimary (citable) accession number: B9SCJ7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2009
Last sequence update: March 23, 2009
Last modified: January 6, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.