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Protein

Histone deacetylase

Gene

RCOM_1509350

Organism
Ricinus communis (Castor bean)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei112SubstrateUniRule annotation1
Active sitei154Proton acceptorUniRule annotation1
Binding sitei162Substrate; via carbonyl oxygenUniRule annotation1
Metal bindingi189Divalent metal cationUniRule annotation1
Metal bindingi191Divalent metal cationUniRule annotation1
Metal bindingi277Divalent metal cationUniRule annotation1
Binding sitei316SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorUniRule annotationSAAS annotation, HydrolaseUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotationSAAS annotation (EC:3.5.1.98UniRule annotationSAAS annotation)
Gene namesi
ORF Names:RCOM_1509350Imported
OrganismiRicinus communis (Castor bean)Imported
Taxonomic identifieri3988 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeAcalyphoideaeAcalypheaeRicinus
Proteomesi
  • UP000008311 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB9RAW2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 330Hist_deacetylInterPro annotationAdd BLAST292

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

InParanoidiB9RAW2.
KOiK06067.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
IPR037138. His_deacetylse_dom_sf.
IPR023696. Ureohydrolase_domain.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
SUPFAMiSSF52768. SSF52768. 1 hit.

Sequencei

Sequence statusi: Complete.

B9RAW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDETGGASL PSTGTDAKKR RVTYFYEPTI GNYYYGQGHP MKPHRIRMAH
60 70 80 90 100
NLIVHYSLHR RMEINRPFPA STIDIRKFHS DDYVDFLSSV SPESLADPAH
110 120 130 140 150
NRHLKRFNVG EDCPVFDGLF GFCQASAGGS MGAAVKLNRG DADIALNWAG
160 170 180 190 200
GLHHAKKSEA SGFCYVNDIV LGILELLKVH RRVLYVDIDV HHGDGVEEAF
210 220 230 240 250
YTTDRVMTVS FHKFGDFFPG TGHIKDTGAG QGKNYALNIP LNDGMDDVSF
260 270 280 290 300
RALFRPIIQK VMEVYQPDAV VLQCGADSLT GDRLGCFNLS VKGHADCLRF
310 320 330 340 350
LRSFNVPLMV LGGGGYTIRN VARCWCYETA VAVGVEPDNK LPYNEYYEYF
360 370 380 390 400
GPDYTLHIDP SNMENLNSPK DMERIRNILL EQLSKLPNAP SVPFQTTPAI
410 420 430 440 450
TEVPEEGDEE MDRRPKRRIW DGEGYESPDE DEKPQPRRLN SDGLVAKDEM
460
RDHIDEMEED KKDVHPQC
Length:468
Mass (Da):52,640
Last modified:March 24, 2009 - v1
Checksum:i023FBF7ABA30135A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973773 Genomic DNA. Translation: EEF51939.1.
RefSeqiXP_002511337.1. XM_002511291.2.

Genome annotation databases

GeneIDi8278303.
KEGGircu:8278303.

Similar proteinsi

Entry informationi

Entry nameiB9RAW2_RICCO
AccessioniPrimary (citable) accession number: B9RAW2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: October 25, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported