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Protein

Histone deacetylase

Gene

RCOM_1509350

Organism
Ricinus communis (Castor bean)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

  1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
  2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
  3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
  4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
ORF Names:RCOM_1509350Imported
OrganismiRicinus communis (Castor bean)Imported
Taxonomic identifieri3988 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeAcalyphoideaeAcalypheaeRicinus
ProteomesiUP000008311 Componenti: Unassembled WGS sequence

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB9RAW2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

InParanoidiB9RAW2.
KOiK06067.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

B9RAW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDETGGASL PSTGTDAKKR RVTYFYEPTI GNYYYGQGHP MKPHRIRMAH
60 70 80 90 100
NLIVHYSLHR RMEINRPFPA STIDIRKFHS DDYVDFLSSV SPESLADPAH
110 120 130 140 150
NRHLKRFNVG EDCPVFDGLF GFCQASAGGS MGAAVKLNRG DADIALNWAG
160 170 180 190 200
GLHHAKKSEA SGFCYVNDIV LGILELLKVH RRVLYVDIDV HHGDGVEEAF
210 220 230 240 250
YTTDRVMTVS FHKFGDFFPG TGHIKDTGAG QGKNYALNIP LNDGMDDVSF
260 270 280 290 300
RALFRPIIQK VMEVYQPDAV VLQCGADSLT GDRLGCFNLS VKGHADCLRF
310 320 330 340 350
LRSFNVPLMV LGGGGYTIRN VARCWCYETA VAVGVEPDNK LPYNEYYEYF
360 370 380 390 400
GPDYTLHIDP SNMENLNSPK DMERIRNILL EQLSKLPNAP SVPFQTTPAI
410 420 430 440 450
TEVPEEGDEE MDRRPKRRIW DGEGYESPDE DEKPQPRRLN SDGLVAKDEM
460
RDHIDEMEED KKDVHPQC
Length:468
Mass (Da):52,640
Last modified:March 23, 2009 - v1
Checksum:i023FBF7ABA30135A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973773 Genomic DNA. Translation: EEF51939.1.
RefSeqiXP_002511337.1. XM_002511291.1.

Genome annotation databases

GeneIDi8278303.
KEGGircu:RCOM_1509350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973773 Genomic DNA. Translation: EEF51939.1.
RefSeqiXP_002511337.1. XM_002511291.1.

3D structure databases

ProteinModelPortaliB9RAW2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8278303.
KEGGircu:RCOM_1509350.

Phylogenomic databases

InParanoidiB9RAW2.
KOiK06067.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. HaleImported.

Entry informationi

Entry nameiB9RAW2_RICCO
AccessioniPrimary (citable) accession number: B9RAW2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 23, 2009
Last sequence update: March 23, 2009
Last modified: March 3, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.