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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

BN1205_106050

Organism
Toxoplasma gondii (strain ATCC 50861 / VEG)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:BN1205_106050Imported, TGVEG_210260Imported
OrganismiToxoplasma gondii (strain ATCC 50861 / VEG)Imported
Taxonomic identifieri432359 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
Proteomesi
  • UP000002226 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiToxoDB:TGME49_210260.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5811.TGME49_010260.

Structurei

3D structure databases

ProteinModelPortaliA0A0F7V147.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini18 – 188171NAD_Gly3P_dh_NInterPro annotationAdd
BLAST
Domaini211 – 358148NAD_Gly3P_dh_CInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili423 – 45028Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiB9Q3A5.
KOiK00006.
OMAiTIEVEIC.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9Q3A5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPRRPSLFQ VLQSGPLKVS VVGSGNWGSV IAKIVALNAQ KSYVFHNEVR
60 70 80 90 100
MWVYEEMVDG EKLTDIINKT HENRKYLPGH KLPENLVALP DVVEACRDSD
110 120 130 140 150
LLIFIMPHQF ATKVCEQLAE ARVVPGHARA ITLLKGLHVE NGKPTLFSDI
160 170 180 190 200
FKTKLDIVDC CVLSGANVAN DVAREEFAEA TIGYSPEETD AALIWQQLFD
210 220 230 240 250
TPYFKVNALP DVAGVQVCGA VKNVIAIAAG FCDGLGLGTN AKTAIIRLGV
260 270 280 290 300
EEMKQFAMIF FDNIMAETFF DSAGYADVIT TVFGGRNARC AAEFLRRGGK
310 320 330 340 350
ATWDQIEADL LKGQKLQGTL TTKEVYEVIA AYEVERLFPL FSVTYEIAFN
360 370 380 390 400
GRDPNDLIRV FKTSEVRQHK TLQECNQLVV SSVVANAKEK MFGEGLPPEG
410 420 430 440 450
REAIEAPDGS LVDEPEAKLV QQQFKLQQQL QQLQHQQQQM QQQLHIMHNN
460 470 480 490 500
NGPLGGHRDC QSPQQLTVHL SHLTPSQRMQ VHRLQQQLQY RQIHKGQDRA
510
PSTPMGHPEL GRNSL
Length:515
Mass (Da):57,420
Last modified:March 24, 2009 - v1
Checksum:i7343FBF1831CA6C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN714499 Genomic DNA. Translation: CEL76148.1.
AAYL02000356 Genomic DNA. Translation: ESS28370.1.

Genome annotation databases

EnsemblProtistsiEPR59640; EPR59640; TGGT1_210260.
ESS28370; ESS28370; TGVEG_210260.
KEGGitgo:TGME49_010260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN714499 Genomic DNA. Translation: CEL76148.1.
AAYL02000356 Genomic DNA. Translation: ESS28370.1.

3D structure databases

ProteinModelPortaliA0A0F7V147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5811.TGME49_010260.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEPR59640; EPR59640; TGGT1_210260.
ESS28370; ESS28370; TGVEG_210260.
KEGGitgo:TGME49_010260.

Organism-specific databases

EuPathDBiToxoDB:TGME49_210260.

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiB9Q3A5.
KOiK00006.
OMAiTIEVEIC.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: VEGImported.
  2. "Annotation of Toxoplasma gondii VEG."
    Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.
    Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 50861 / VEGImported.
  3. Gandolfi B., Grahn R.A.
    Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: VEGImported.
  4. "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel Transcript Features."
    Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A., Vermont S.J., Otto T.D., Wastling J., Pain A.
    PLoS ONE 10:e0124473-e0124473(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: VEGImported.

Entry informationi

Entry nameiB9Q3A5_TOXGV
AccessioniPrimary (citable) accession number: B9Q3A5
Secondary accession number(s): A0A0F7V147
, A0A0N5EBS2, B6KVG5, B9QQY9, S7UPJ7, S8GI96
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 8, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.