ID   B9PW60_TOXGV            Unreviewed;       330 AA.
AC   B9PW60; A0A0F7V310; B6KM92; B9Q764; S7UQN3; S8EZR4;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 87.
DE   SubName: Full=Sedoheptulose-1,7 bisphosphatase, putative {ECO:0000313|EMBL:CEL76880.1};
DE   SubName: Full=Sedoheptulose-1,7-bisphosphatase {ECO:0000313|EMBL:ESS30937.1};
DE            EC=3.1.3.37 {ECO:0000313|EMBL:ESS30937.1};
GN   ORFNames=BN1205_061570 {ECO:0000313|EMBL:CEL76880.1}, TGVEG_235700
GN   {ECO:0000313|EMBL:ESS30937.1};
OS   Toxoplasma gondii (strain ATCC 50861 / VEG).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX   NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS30937.1, ECO:0000313|Proteomes:UP000002226};
RN   [1] {ECO:0000313|EMBL:ESS30937.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=VEG {ECO:0000313|EMBL:ESS30937.1};
RA   Paulsen I.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA   Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT   "Annotation of Toxoplasma gondii VEG.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0007829|PDB:4IR8}
RP   X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).
RG   Center for Structural Genomics of Infectious Diseases (CSGID);
RA   Minasov G., Ruan J., Wawrzak Z., Halavaty A., Shuvalova L., Harb O.S.,
RA   Ngo H., Anderson W.F.;
RT   "1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7
RT   bisphosphatase from Toxoplasma gondii.";
RL   Submitted (JAN-2013) to the PDB data bank.
RN   [4] {ECO:0000313|EMBL:ESS30937.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=VEG {ECO:0000313|EMBL:ESS30937.1};
RA   Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA   Roos D., Caler E., Lorenzi H.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:CEL76880.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=VEG {ECO:0000313|EMBL:CEL76880.1};
RX   PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA   Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA   Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT   "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT   Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT   Transcript Features.";
RL   PLoS ONE 10:e0124473-e0124473(2015).
CC   -!- PATHWAY: Carbohydrate biosynthesis. {ECO:0000256|ARBA:ARBA00024331}.
CC   -!- SIMILARITY: Belongs to the FBPase class 1 family.
CC       {ECO:0000256|ARBA:ARBA00010941}.
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DR   EMBL; LN714500; CEL76880.1; -; Genomic_DNA.
DR   EMBL; AAYL02000213; ESS30937.1; -; Genomic_DNA.
DR   PDB; 4IR8; X-ray; 1.85 A; A/B=1-330.
DR   PDBsum; 4IR8; -.
DR   AlphaFoldDB; B9PW60; -.
DR   SMR; B9PW60; -.
DR   STRING; 432359.B9PW60; -.
DR   PaxDb; 5811-TGME49_035700; -.
DR   EnsemblProtists; ESS30937; ESS30937; TGVEG_235700.
DR   VEuPathDB; ToxoDB:TGVEG_235700; -.
DR   eggNOG; KOG1458; Eukaryota.
DR   OMA; PNWTVGT; -.
DR   Proteomes; UP000002226; Partially assembled WGS sequence.
DR   GO; GO:0050278; F:sedoheptulose-bisphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.190.80; -; 1.
DR   Gene3D; 3.30.540.10; Fructose-1,6-Bisphosphatase, subunit A, domain 1; 1.
DR   InterPro; IPR044015; FBPase_C_dom.
DR   InterPro; IPR000146; FBPase_class-1.
DR   InterPro; IPR033391; FBPase_N.
DR   InterPro; IPR023079; SBPase.
DR   PANTHER; PTHR11556; FRUCTOSE-1,6-BISPHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR11556:SF35; SEDOHEPTULOSE-1,7-BISPHOSPHATASE, CHLOROPLASTIC; 1.
DR   Pfam; PF00316; FBPase; 1.
DR   Pfam; PF18913; FBPase_C; 1.
DR   PIRSF; PIRSF000904; FBPtase_SBPase; 1.
DR   PRINTS; PR01958; S17BPHPHTASE.
DR   SUPFAM; SSF56655; Carbohydrate phosphatase; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4IR8};
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ESS30937.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002226}.
FT   DOMAIN          11..171
FT                   /note="Fructose-1-6-bisphosphatase class I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00316"
FT   DOMAIN          201..324
FT                   /note="Fructose-1-6-bisphosphatase class 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18913"
SQ   SEQUENCE   330 AA;  35773 MW;  8FC4D87A60EF770D CRC64;
     MESPSALPSL DQLLKEQGAD QTLTDLILAI LDRCGKIASA LQGTSVDKVG SVNEFGDEQL
     TVDVIAENLL RSWAQSSEGS AVRAVCSEED IHLQECHKNG EFILCWDPLD GSSIIDCNWA
     VGSIVSIWRI GHHGVQWQGA DTLIQKTGRQ QVASLIVVYG PRTTGVVAVN VDAGGIVKEG
     TALDLEMKDN GKFICRGKPI IKPQAKIFSP ANLRAAQDLP AYKQLIEFWM EKRYTLRYTG
     GLVPDVYQIF VKQQGVFCNP ASKAAPAKLR MCFEVLAIAL VVEAAGGRTS NGQKSLLDVA
     IEHMDHRSAL CCGSADEIKR MEETFAALSG
//