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B9MPG8 (XYLA_CALBD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:Athe_0603
OrganismCaldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320) (Anaerocellum thermophilum) [Complete proteome] [HAMAP]
Taxonomic identifier521460 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Caldicellulosiruptor ›

Protein attributes

Sequence length438 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 438438Xylose isomerase HAMAP-Rule MF_00455
PRO_1000200276

Sites

Metal binding3061Magnesium 2 By similarity
Metal binding3081Magnesium 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
B9MPG8 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: FA35A4517EE39CFA

FASTA43850,089
        10         20         30         40         50         60 
MKYFKDIPEV KYEGPQSDNP FAFKYYNPDE IIDGKPLKDH LRFAIAYWHT FCATGSDPFG 

        70         80         90        100        110        120 
QPTIVRPWDK FSNRMDNAKA RVEAAFEFFE LLDVPFFCFH DRDIAPEGEN LKESNKNLDE 

       130        140        150        160        170        180 
IVSLIKEYLK TSKTKVLWGT ANLFSHPRYV HGAATSCNAD VFAYAAAQVK KALEVTKELG 

       190        200        210        220        230        240 
GENYVFWGGR EGYETLLNTD MGLELDNLAR FLHMAVEYAK EIGFDGQFLI EPKPKEPTKH 

       250        260        270        280        290        300 
QYDFDSAHVY GFLKKYDLDK YFKLNIEVNH ATLAGHDFHH ELRFARINNM LGSIDANMGD 

       310        320        330        340        350        360 
LLLGWDTDQF PTDVRLTTLA MYEVIKAGGF DKGGLNFDAK VRRGSFELED LVIGHIAGMD 

       370        380        390        400        410        420 
AFAKGFKIAY KLVKDGVFDK FIDERYKSYK EGIGAKIVSG EANFKMLEEY ALSLDKIENK 

       430 
SGKQELLEMI LNKYMFSE

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References

[1]"Complete sequence of chromosome of Anaerocellum thermophilum DSM 6725."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Kataeva I., Adams M.W.W.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1888 / DSM 6725 / Z-1320.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001393 Genomic DNA. Translation: ACM59729.1.
RefSeqYP_002572502.1. NC_012034.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING521460.Athe_0603.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM59729; ACM59729; Athe_0603.
GeneID7406944.
KEGGate:Athe_0603.
PATRIC20898226. VBIAnaThe135187_0636.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMAHTFQHEL.
ProtClustDBCLSK986031.

Enzyme and pathway databases

BioCycCBES521460:GH8H-626-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_CALBD
AccessionPrimary (citable) accession number: B9MPG8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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