Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable 5-dehydro-4-deoxyglucarate dehydratase

Gene

Dtpsy_1793

Organism
Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2.UniRule annotation

Pathwayi: D-glucarate degradation

This protein is involved in step 2 of the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable 5-dehydro-4-deoxyglucarate dehydratase (Dtpsy_1793)
This subpathway is part of the pathway D-glucarate degradation, which is itself part of Carbohydrate acid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate, the pathway D-glucarate degradation and in Carbohydrate acid metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciAEBR535289:GHOO-1824-MONOMER.
UniPathwayiUPA00564; UER00628.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 5-dehydro-4-deoxyglucarate dehydrataseUniRule annotation (EC:4.2.1.41UniRule annotation)
Alternative name(s):
5-keto-4-deoxy-glucarate dehydrataseUniRule annotation
Short name:
KDGDHUniRule annotation
Gene namesi
Ordered Locus Names:Dtpsy_1793
OrganismiAcidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Taxonomic identifieri535289 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000000450 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Probable 5-dehydro-4-deoxyglucarate dehydratasePRO_1000147907Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi535289.Dtpsy_1793.

Structurei

3D structure databases

ProteinModelPortaliB9MJB2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DapA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105UVJ. Bacteria.
COG0329. LUCA.
HOGENOMiHOG000173605.
KOiK01707.
OMAiRNRKKGY.
OrthoDBiPOG091H00C1.

Family and domain databases

CDDicd00951. KDGDH. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00694. KDGDH. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
IPR017655. Dehydro-deoxyglucarate_dehyd.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
SMARTiSM01130. DHDPS. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03249. KdgD. 1 hit.

Sequencei

Sequence statusi: Complete.

B9MJB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPQDLKNVM SSGLLSFPIT DFHDNGDFNA KGYAERLEWL APFGASALFA
60 70 80 90 100
AGGTGEYFSL TASEYPQIIQ TAVNTCRGKV PIIAGAGGPT RFAIECAQAA
110 120 130 140 150
EKAGAHGILL MPHYMTEASQ EGLAAHVEAV CKSVNFGVII YNRGITRYTP
160 170 180 190 200
ETVARLCERN PNLVGFKDGV GDIEGMASMF LAMGDRLAYL GGLPTAEVYA
210 220 230 240 250
AAYKALGTPV YSSAVFNFIP KTAMRFYEAV KNDDQATQHQ LLKDFFMPYL
260 270 280 290 300
KIRNRSAGYA VSIIKAGAKI VGHPAGPVRA PLADLQAEEI EMLAELIRKV

EPV
Length:303
Mass (Da):32,622
Last modified:March 24, 2009 - v1
Checksum:i838922BE534B4D08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001392 Genomic DNA. Translation: ACM33250.1.
RefSeqiWP_011805237.1. NC_011992.1.

Genome annotation databases

EnsemblBacteriaiACM33250; ACM33250; Dtpsy_1793.
KEGGidia:Dtpsy_1793.
PATRICi21780693. VBIDiaSp55748_1833.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001392 Genomic DNA. Translation: ACM33250.1.
RefSeqiWP_011805237.1. NC_011992.1.

3D structure databases

ProteinModelPortaliB9MJB2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi535289.Dtpsy_1793.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACM33250; ACM33250; Dtpsy_1793.
KEGGidia:Dtpsy_1793.
PATRICi21780693. VBIDiaSp55748_1833.

Phylogenomic databases

eggNOGiENOG4105UVJ. Bacteria.
COG0329. LUCA.
HOGENOMiHOG000173605.
KOiK01707.
OMAiRNRKKGY.
OrthoDBiPOG091H00C1.

Enzyme and pathway databases

UniPathwayiUPA00564; UER00628.
BioCyciAEBR535289:GHOO-1824-MONOMER.

Family and domain databases

CDDicd00951. KDGDH. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00694. KDGDH. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
IPR017655. Dehydro-deoxyglucarate_dehyd.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
SMARTiSM01130. DHDPS. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03249. KdgD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKDGD_ACIET
AccessioniPrimary (citable) accession number: B9MJB2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: September 7, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.