Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B9MF68

- GSA_ACIET

UniProt

B9MF68 - GSA_ACIET

Protein

Glutamate-1-semialdehyde 2,1-aminomutase

Gene

hemL

Organism
Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (24 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: InterPro
    3. transaminase activity Source: InterPro

    GO - Biological processi

    1. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Porphyrin biosynthesis

    Keywords - Ligandi

    Pyridoxal phosphate

    Enzyme and pathway databases

    BioCyciAEBR535289:GHOO-2950-MONOMER.
    UniPathwayiUPA00251; UER00317.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate-1-semialdehyde 2,1-aminomutaseUniRule annotation (EC:5.4.3.8UniRule annotation)
    Short name:
    GSAUniRule annotation
    Alternative name(s):
    Glutamate-1-semialdehyde aminotransferaseUniRule annotation
    Short name:
    GSA-ATUniRule annotation
    Gene namesi
    Name:hemLUniRule annotation
    Ordered Locus Names:Dtpsy_2904
    OrganismiAcidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
    Taxonomic identifieri535289 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
    ProteomesiUP000000450: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 434434Glutamate-1-semialdehyde 2,1-aminomutasePRO_1000201017Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei274 – 2741N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi535289.Dtpsy_2904.

    Structurei

    3D structure databases

    ProteinModelPortaliB9MF68.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0001.
    HOGENOMiHOG000020210.
    KOiK01845.
    OMAiRITSENG.
    OrthoDBiEOG6QVRHN.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 2 hits.
    HAMAPiMF_00375. HemL_aminotrans_3.
    InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR00713. hemL. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B9MF68-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTHNTDLNLP LFERAKALIP GGVNSPVRAF RAVGGTPRFI TRAQGAYMWD    50
    ANGQRFIDYI GSWGPMILGH GHPAVLEAVQ KAALEGFSFG APTEREVELA 100
    EEIIRHVPSM EMIRLVSSGT EAGMSAIRLA RGATRRNKII KFNGCYHGHA 150
    DSLLVKAGSG LATFGHATSA GVPQEVVQHT LVLEYNDVAQ LEEAFTLHGP 200
    DVACVIMEPI AGNMNFVRAS VPFMRRAREL CTQHGALLVI DEVMTGFRVA 250
    LGGAQSLYAQ AIPGFKPDIT VLGKVIGGGM PLAAFGGSRA VMEQLAPLGP 300
    VYQAGTLSGN PVATACGLAT LREIAKPGFY DALGARTRAL IDGLAGAASA 350
    AGVPFCGDTQ GGMFGFFLLP QLPQNYPEVL NTDGMRFNTL FHGLLDGGVY 400
    IAPALYEAGF VSAAHTEQDI ADTVAVARDV FQKL 434
    Length:434
    Mass (Da):45,949
    Last modified:March 24, 2009 - v1
    Checksum:iDF6CC7922242EB94
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001392 Genomic DNA. Translation: ACM34338.1.
    RefSeqiYP_002554338.1. NC_011992.1.

    Genome annotation databases

    EnsemblBacteriaiACM34338; ACM34338; Dtpsy_2904.
    GeneIDi7384089.
    KEGGidia:Dtpsy_2904.
    PATRICi21782953. VBIDiaSp55748_2947.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001392 Genomic DNA. Translation: ACM34338.1 .
    RefSeqi YP_002554338.1. NC_011992.1.

    3D structure databases

    ProteinModelPortali B9MF68.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 535289.Dtpsy_2904.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACM34338 ; ACM34338 ; Dtpsy_2904 .
    GeneIDi 7384089.
    KEGGi dia:Dtpsy_2904.
    PATRICi 21782953. VBIDiaSp55748_2947.

    Phylogenomic databases

    eggNOGi COG0001.
    HOGENOMi HOG000020210.
    KOi K01845.
    OMAi RITSENG.
    OrthoDBi EOG6QVRHN.

    Enzyme and pathway databases

    UniPathwayi UPA00251 ; UER00317 .
    BioCyci AEBR535289:GHOO-2950-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 2 hits.
    HAMAPi MF_00375. HemL_aminotrans_3.
    InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR00713. hemL. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TPSY.

    Entry informationi

    Entry nameiGSA_ACIET
    AccessioniPrimary (citable) accession number: B9MF68
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 24, 2009
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3