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Protein

Transaldolase

Gene

tal

Organism
Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei125 – 1251Schiff-base intermediate with substrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Pentose shunt

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciAEBR535289:GHOO-676-MONOMER.
UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:Dtpsy_0674
OrganismiAcidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Taxonomic identifieri535289 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000000450 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316TransaldolasePRO_1000198453Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi535289.Dtpsy_0674.

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0176.
HOGENOMiHOG000281234.
KOiK00616.
OMAiQRGIHTN.
OrthoDBiEOG6G7R4D.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00492. Transaldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004730. Transaldolase_1.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00874. talAB. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9MDC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQLDALKQY TTVVADTGDF KQLAQFQPQD ATTNPSLILK AVQKPEYAPL
60 70 80 90 100
LKDCVTRWHG RAIDELMDRL IVRFGCEILS IIPGRVSTEV DARLSFDTAA
110 120 130 140 150
TVARAERIVE LYQAEGLHID RVLIKIAATW EGIQAARQLE QRGIHTNLTL
160 170 180 190 200
LFSFAQAVAC GQAKVQLISP FVGRIYDWYK KQAGANWDEA AMAGANDPGV
210 220 230 240 250
QSVRAIYNHY KHFGIGTEVM GASFRNTGQI VALAGCDLLT IAPELLAQLA
260 270 280 290 300
ASDAPVARVL DPEAARRVAL QPVQYDEAGF RYALNADAMA TEKLAEGIRA
310
FAADAAKLEQ LMQAAA
Length:316
Mass (Da):34,486
Last modified:March 24, 2009 - v1
Checksum:i80DA983924EA5258
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001392 Genomic DNA. Translation: ACM32154.1.
RefSeqiWP_012655675.1. NC_011992.1.
YP_002552154.1. NC_011992.1.

Genome annotation databases

EnsemblBacteriaiACM32154; ACM32154; Dtpsy_0674.
KEGGidia:Dtpsy_0674.
PATRICi21778363. VBIDiaSp55748_0696.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001392 Genomic DNA. Translation: ACM32154.1.
RefSeqiWP_012655675.1. NC_011992.1.
YP_002552154.1. NC_011992.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi535289.Dtpsy_0674.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACM32154; ACM32154; Dtpsy_0674.
KEGGidia:Dtpsy_0674.
PATRICi21778363. VBIDiaSp55748_0696.

Phylogenomic databases

eggNOGiCOG0176.
HOGENOMiHOG000281234.
KOiK00616.
OMAiQRGIHTN.
OrthoDBiEOG6G7R4D.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.
BioCyciAEBR535289:GHOO-676-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00492. Transaldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004730. Transaldolase_1.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00874. talAB. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TPSY.

Entry informationi

Entry nameiTAL_ACIET
AccessioniPrimary (citable) accession number: B9MDC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 27, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.