B9MDC2 (TAL_ACIET) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Dtpsy_0674

Organism

Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)) [Complete proteome] [HAMAP]

Taxonomic identifier

535289 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax › Acidovorax ebreus

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP-Rule MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP-Rule MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP-Rule MF_00492
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	Transaldolase HAMAP-Rule MF_00492		PRO_1000198453
Sites
	Active site	125	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B9MDC2 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 80DA983924EA5258	FASTA	316	34,486
	10 20 30 40 50 60 MNQLDALKQY TTVVADTGDF KQLAQFQPQD ATTNPSLILK AVQKPEYAPL LKDCVTRWHG 70 80 90 100 110 120 RAIDELMDRL IVRFGCEILS IIPGRVSTEV DARLSFDTAA TVARAERIVE LYQAEGLHID 130 140 150 160 170 180 RVLIKIAATW EGIQAARQLE QRGIHTNLTL LFSFAQAVAC GQAKVQLISP FVGRIYDWYK 190 200 210 220 230 240 KQAGANWDEA AMAGANDPGV QSVRAIYNHY KHFGIGTEVM GASFRNTGQI VALAGCDLLT 250 260 270 280 290 300 IAPELLAQLA ASDAPVARVL DPEAARRVAL QPVQYDEAGF RYALNADAMA TEKLAEGIRA 310 FAADAAKLEQ LMQAAA

References

[1]

"Complete sequence of Diaphorobacter sp. TPSY." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Coates J.D. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TPSY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001392 Genomic DNA. Translation: ACM32154.1.
RefSeq	YP_002552154.1. NC_011992.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	535289.Dtpsy_0674.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACM32154; ACM32154; Dtpsy_0674.
GeneID	7384179.
KEGG	dia:Dtpsy_0674.
PATRIC	21778363. VBIDiaSp55748_0696.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
HOGENOM	HOG000281234.
KO	K00616.
OMA	RYQTVIM.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	AEBR535289:GHOO-676-MONOMER.
UniPathway	UPA00115; UER00414.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00492. Transaldolase_1.
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
PANTHER	PTHR10683. PTHR10683. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. talAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_ACIET

Accession

Primary (citable) accession number: B9MDC2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program