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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei160 – 1601UniRule annotation
Active sitei602 – 6021UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAEBR535289:GHOO-2418-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Dtpsy_2376Imported
OrganismiAcidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))Imported
Taxonomic identifieri535289 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000000450 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi535289.Dtpsy_2376.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9MCA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPARKTDA AAASAPARKT DKDLPLIQDI RLLGRILGDV IREQEGVAAY
60 70 80 90 100
DLVEQVRKLS VAFRRDADHE ADKALKKLLK GLTGDQTVSV IRAFTYFSHL
110 120 130 140 150
ANLAEDRHHI RRRAVHERAG SAQEGSIEVA LARLRWAGIA PRTVAQTLAT
160 170 180 190 200
SYVAPVLTAH PTEVQRKSIL DAEREIALLL TQRDDIQARA QLYNSAKDTL
210 220 230 240 250
TPRELAANEA QLRARVAQLW QTRLLRYSKL TVADEIENAL SYYEYTFLHE
260 270 280 290 300
IPKIYAELER ELGGSHPVAS FLRMGQWIGG DRDGNPNVSA DTLALALRRQ
310 320 330 340 350
AEVALRHYLT EVHHLGRELS LSSNLVQVSA EMLQLAARSP DTSEHRRDEP
360 370 380 390 400
YRRALTGVYA RLAATLRDLT GGEAARHAVA PQNAYASAGD FLADLRVIEA
410 420 430 440 450
SLRSHRGAAL VGERLRPLMR AVEVFGFHLA TVDLRQSSDQ HERVVAELLA
460 470 480 490 500
TARVESDYEA LPEPARRALL LRLLCDARPL RVVGAPYSEH TTGEVAIFET
510 520 530 540 550
ARQMRERYGD DAIRHYIISH TETVSDLLEV LLLQKEVGLL QGTLDTGARA
560 570 580 590 600
DLIVVPLFET IEDLRNAAPI MREFYAIPGI AQLVRASGAE QDIMLGYSDS
610 620 630 640 650
NKDGGIFTSN WELYRAEIAL VALFDEMNAA QAGTPIQLRM FHGRGGTVGR
660 670 680 690 700
GGGPSYQAIL AQPPGTVRGQ IRLTEQGEVI ASKYANPEIG RRNLETLVAA
710 720 730 740 750
TLEATLLQPT KSATKAFLEA AEQLSQASME AYRALVYETP GFTDYFFNST
760 770 780 790 800
PIREIAELNI GSRPASRKAS QQIEDLRAIP WGFSWGQCRL TLPGWFGFGA
810 820 830 840 850
AVDAFTHAPG KDPKAQLALL QKMYRQWPFF RTLLSNMDMV LAKSDLALAS
860 870 880 890 900
RYSELVADAR LRKKVFGVIE AEWQRTADAL TRITGEKQRL AANTALARSI
910 920 930 940
RHRFPYIDPL HHLQVELVRR WRAGQGDERV QTGIHISING IAAGLRNTG
Length:949
Mass (Da):105,240
Last modified:March 24, 2009 - v1
Checksum:i94FF06E0FA338EB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001392 Genomic DNA. Translation: ACM33813.1.
RefSeqiYP_002553813.1. NC_011992.1.

Genome annotation databases

EnsemblBacteriaiACM33813; ACM33813; Dtpsy_2376.
KEGGidia:Dtpsy_2376.
PATRICi21781871. VBIDiaSp55748_2411.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001392 Genomic DNA. Translation: ACM33813.1.
RefSeqiYP_002553813.1. NC_011992.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi535289.Dtpsy_2376.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACM33813; ACM33813; Dtpsy_2376.
KEGGidia:Dtpsy_2376.
PATRICi21781871. VBIDiaSp55748_2411.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciAEBR535289:GHOO-2418-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TPSYImported.

Entry informationi

Entry nameiB9MCA8_ACIET
AccessioniPrimary (citable) accession number: B9MCA8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: April 1, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.