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B9MBT5 (UBIA_ACIET) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
4-hydroxybenzoate octaprenyltransferase

EC=2.5.1.-
Alternative name(s):
4-HB polyprenyltransferase
Gene names
Name:ubiA
Ordered Locus Names:Dtpsy_0371
OrganismAcidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY)) [Complete proteome] [HAMAP]
Taxonomic identifier535289 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax

Protein attributes

Sequence length290 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesis of 3-octaprenyl-4-hydroxybenzoate By similarity. HAMAP-Rule MF_01635

Catalytic activity

4-hydroxybenzoate + farnesylfarnesylgeraniol = 3-octaprenyl-4-hydroxybenzoate. HAMAP-Rule MF_01635

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01635

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP-Rule MF_01635

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01635.

Sequence similarities

Belongs to the UbiA prenyltransferase family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   LigandMagnesium
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprenyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2902904-hydroxybenzoate octaprenyltransferase HAMAP-Rule MF_01635
PRO_1000186662

Regions

Transmembrane21 – 4020Helical; Potential
Transmembrane45 – 6420Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane116 – 13621Helical; Potential
Transmembrane138 – 15821Helical; Potential
Transmembrane165 – 18521Helical; Potential
Transmembrane212 – 23221Helical; Potential
Transmembrane237 – 25721Helical; Potential
Transmembrane269 – 28921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
B9MBT5 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 25501D3A6D1BE78D

FASTA29031,925
        10         20         30         40         50         60 
MSAVAPRSRL SLYLDLIRWN RPAGWLVLVW PTLAALWVAA DGFPGWHLLA VFVAGTVLMR 

        70         80         90        100        110        120 
SAGCTINDIA DRDFDRHVKR TTQRPITSGQ LGVREAALVG VVLTLVAFVL VLTTRWEAVA 

       130        140        150        160        170        180 
WSVPAVLFTI LYPFTKRFFA MPQAFLGIAF NFGIVIAFAA VQGRVPATAW VLWLANLFLV 

       190        200        210        220        230        240 
LAYDTEYAMV DRDDDLKIGM KTSAITLGRF DVAAIMGFFV LCLGLTAWVL APYGLGWPLW 

       250        260        270        280        290 
LGLGVAAAQV AWHFTLIKDR TREGCFTAFS KSHWIGAAIF AGVALGYLLR 

« Hide

References

[1]"Complete sequence of Diaphorobacter sp. TPSY."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Coates J.D.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TPSY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001392 Genomic DNA. Translation: ACM31855.1.
RefSeqYP_002551855.1. NC_011992.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING535289.Dtpsy_0371.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM31855; ACM31855; Dtpsy_0371.
GeneID7385379.
KEGGdia:Dtpsy_0371.
PATRIC21777738. VBIDiaSp55748_0385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0382.
HOGENOMHOG000003696.
KOK03179.
OMALANIFWA.
OrthoDBEOG680X3B.

Enzyme and pathway databases

BioCycAEBR535289:GHOO-372-MONOMER.
UniPathwayUPA00232.

Family and domain databases

HAMAPMF_01635. UbiA.
InterProIPR006370. HB_polyprenyl-transferase.
IPR000537. UbiA_prenyltransferase.
[Graphical view]
PfamPF01040. UbiA. 1 hit.
[Graphical view]
TIGRFAMsTIGR01474. ubiA_proteo. 1 hit.
PROSITEPS00943. UBIA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIA_ACIET
AccessionPrimary (citable) accession number: B9MBT5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways