tuf

Functionⁱ

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature key	Position(s)	DescriptionActions	Length
Nucleotide bindingⁱ	19 – 26	GTPUniRule annotation	8
Nucleotide bindingⁱ	81 – 85	GTPUniRule annotation	5
Nucleotide bindingⁱ	136 – 139	GTPUniRule annotation	4

GO - Molecular functionⁱ

GTPase activity Source: InterPro
GTP binding Source: UniProtKB-HAMAP
translation elongation factor activity Source: UniProtKB-HAMAP

Complete GO annotation...

Keywordsⁱ

Molecular function	Elongation factorUniRule annotationImported
Biological process	Protein biosynthesis
Ligand	GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Elongation factor TuUniRule annotation Short name: EF-TuUniRule annotation
Gene namesⁱ	Name:tufUniRule annotation Ordered Locus Names:Dtpsy_0271Imported, Dtpsy_3253Imported
Organismⁱ	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))Imported
Taxonomic identifierⁱ	535289 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax › Acidovorax ebreus
Proteomesⁱ	UP000000450 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Automatic assertion according to rulesⁱ
- HAMAP-Rule:MF_00118

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

CytoplasmUniRule annotation

Interactionⁱ

Subunit structureⁱ

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGⁱ	535289.Dtpsy_3253.

STRINGⁱ

535289.Dtpsy_3253.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	10 – 206	Tr-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST		197

Sequence similaritiesⁱ

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105CGV. Bacteria. COG0050. LUCA.
HOGENOMⁱ	HOG000229290.
KEGG Orthology (KO) More...KOⁱ	K02358.
OMAⁱ	YGHIDCP.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00LA.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03697. EFTU_II. 1 hit.
HAMAPⁱ	MF_00118_B. EF_Tu_B. 1 hit.
InterProⁱ	View protein in InterPro IPR004161. EFTu-like_2. IPR033720. EFTU_2. IPR031157. G_TR_CS. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR000795. TF_GTP-bd_dom. IPR009000. Transl_B-barrel. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit.
PRINTSⁱ	PR00315. ELONGATNFCT.
SUPFAMⁱ	SSF50447. SSF50447. 1 hit. SSF50465. SSF50465. 1 hit. SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00301. G_TR_1. 1 hit. PS51722. G_TR_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

B9MB71-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AIATVLSKKF GGEAKGYDQI 
        60         70         80         90        100
DNAPEEKARG ITINTSHVEY ETATRHYAHV DCPGHADYVK NMITGAAQMD 
       110        120        130        140        150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFLNKCDM VDDEELLELV 
       160        170        180        190        200
EMEVRELLDK YDFPGDDTPI IRGSAKLALE GDQSDKGEPA IMRLAEALDT 
       210        220        230        240        250
YIPTPERAVD GAFLMPVEDV FSISGRGTVV TGRVERGIIK VGEEIEIVGI 
       260        270        280        290        300
RDTQKTTVTG VEMFRKLLDQ GQAGDNVGLL LRGTKREDVE RGQVLCKPGS 
       310        320        330        340        350
IKPHTHFTAE VYVLSKDEGG RHTPFFNNYR PQFYFRTTDV TGSIELPADK 
       360        370        380        390 
EMVMPGDNVS ITVKLINPIA MEEGLRFAIR EGGRTVGAGV VAKIIA

Length:396

Mass (Da):43,261

Last modified:March 24, 2009 - v1

Checksum:ⁱ79638198C3C534AC

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP001392 Genomic DNA. Translation: ACM31755.1. CP001392 Genomic DNA. Translation: ACM34682.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_012655361.1. NC_011992.1.

Genome annotation databases

EnsemblBacteriaⁱ	ACM31755; ACM31755; Dtpsy_0271. ACM34682; ACM34682; Dtpsy_3253.
KEGGⁱ	dia:Dtpsy_0271. dia:Dtpsy_3253.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP001392 Genomic DNA. Translation: ACM31755.1. CP001392 Genomic DNA. Translation: ACM34682.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_012655361.1. NC_011992.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	535289.Dtpsy_3253.

STRINGⁱ

535289.Dtpsy_3253.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ACM31755; ACM31755; Dtpsy_0271. ACM34682; ACM34682; Dtpsy_3253.
KEGGⁱ	dia:Dtpsy_0271. dia:Dtpsy_3253.

Phylogenomic databases

eggNOGⁱ	ENOG4105CGV. Bacteria. COG0050. LUCA.
HOGENOMⁱ	HOG000229290.
KEGG Orthology (KO) More...KOⁱ	K02358.
OMAⁱ	YGHIDCP.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00LA.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03697. EFTU_II. 1 hit.
HAMAPⁱ	MF_00118_B. EF_Tu_B. 1 hit.
InterProⁱ	View protein in InterPro IPR004161. EFTu-like_2. IPR033720. EFTU_2. IPR031157. G_TR_CS. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR000795. TF_GTP-bd_dom. IPR009000. Transl_B-barrel. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit.
PRINTSⁱ	PR00315. ELONGATNFCT.
SUPFAMⁱ	SSF50447. SSF50447. 1 hit. SSF50465. SSF50465. 1 hit. SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00301. G_TR_1. 1 hit. PS51722. G_TR_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B9MB71_ACIET
Accessionⁱ	B9MB71Primary (citable) accession number: B9MB71
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 24, 2009
	Last sequence update:	March 24, 2009
	Last modified:	July 5, 2017
	This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - B9MB71 (B9MB71_ACIET)

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Elongation factor Tu

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Functionⁱ

Regions

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Subunit structureⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B9MB71 (B9MB71_ACIET)

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Elongation factor Tu

tuf

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ