UniProtKB - B9MB71 (B9MB71_ACIET)
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Protein
Elongation factor Tu
Gene
tuf
Organism
Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))
Status
Functioni
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 19 – 26 | GTPUniRule annotation | 8 | |
Nucleotide bindingi | 81 – 85 | GTPUniRule annotation | 5 | |
Nucleotide bindingi | 136 – 139 | GTPUniRule annotation | 4 |
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: UniProtKB-UniRule
- translation elongation factor activity Source: UniProtKB-UniRule
Keywordsi
Molecular function | Elongation factorUniRule annotationImported |
Biological process | Protein biosynthesis |
Ligand | GTP-bindingUniRule annotation, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | AEBR535289:G1GUT-272-MONOMER. AEBR535289:G1GUT-3296-MONOMER. |
Names & Taxonomyi
Protein namesi | Recommended name: Elongation factor TuUniRule annotationShort name: EF-TuUniRule annotation |
Gene namesi | Name:tufUniRule annotation Ordered Locus Names:Dtpsy_0271Imported, Dtpsy_3253Imported |
Organismi | Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))Imported |
Taxonomic identifieri | 535289 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Monomer.UniRule annotation
Protein-protein interaction databases
STRINGi | 535289.Dtpsy_3253. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 206 | Tr-type GInterPro annotationAdd BLAST | 197 |
Sequence similaritiesi
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105CGV. Bacteria. COG0050. LUCA. |
HOGENOMi | HOG000229290. |
KOi | K02358. |
OMAi | YGHIDCP. |
OrthoDBi | POG091H00LA. |
Family and domain databases
CDDi | cd03697. EFTU_II. 1 hit. |
HAMAPi | MF_00118_B. EF_Tu_B. 1 hit. |
InterProi | View protein in InterPro IPR004161. EFTu-like_2. IPR033720. EFTU_2. IPR031157. G_TR_CS. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR000795. TF_GTP-bd_dom. IPR009000. Transl_B-barrel_sf. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. |
Pfami | View protein in Pfam PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. |
PRINTSi | PR00315. ELONGATNFCT. |
SUPFAMi | SSF50447. SSF50447. 1 hit. SSF50465. SSF50465. 1 hit. SSF52540. SSF52540. 1 hit. |
TIGRFAMsi | TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit. |
PROSITEi | View protein in PROSITE PS00301. G_TR_1. 1 hit. PS51722. G_TR_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
B9MB71-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AIATVLSKKF GGEAKGYDQI
60 70 80 90 100
DNAPEEKARG ITINTSHVEY ETATRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFLNKCDM VDDEELLELV
160 170 180 190 200
EMEVRELLDK YDFPGDDTPI IRGSAKLALE GDQSDKGEPA IMRLAEALDT
210 220 230 240 250
YIPTPERAVD GAFLMPVEDV FSISGRGTVV TGRVERGIIK VGEEIEIVGI
260 270 280 290 300
RDTQKTTVTG VEMFRKLLDQ GQAGDNVGLL LRGTKREDVE RGQVLCKPGS
310 320 330 340 350
IKPHTHFTAE VYVLSKDEGG RHTPFFNNYR PQFYFRTTDV TGSIELPADK
360 370 380 390
EMVMPGDNVS ITVKLINPIA MEEGLRFAIR EGGRTVGAGV VAKIIA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001392 Genomic DNA. Translation: ACM31755.1. CP001392 Genomic DNA. Translation: ACM34682.1. |
RefSeqi | WP_012655361.1. NC_011992.1. |
Genome annotation databases
EnsemblBacteriai | ACM31755; ACM31755; Dtpsy_0271. ACM34682; ACM34682; Dtpsy_3253. |
KEGGi | dia:Dtpsy_0271. dia:Dtpsy_3253. |
Similar proteinsi
Entry informationi
Entry namei | B9MB71_ACIET | |
Accessioni | B9MB71Primary (citable) accession number: B9MB71 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 24, 2009 |
Last sequence update: | March 24, 2009 | |
Last modified: | March 28, 2018 | |
This is version 67 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |