Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (Geob_1666)
  3. ATP-dependent 6-phosphofructokinase (pfkA), ATP-dependent 6-phosphofructokinase (pfk-1), ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei351UniRule annotation1
Active sitei455UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciGDAL316067:G1GUR-1512-MONOMER
UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Geob_1498
OrganismiGeobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Taxonomic identifieri316067 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000007721 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001355301 – 530Glucose-6-phosphate isomeraseAdd BLAST530

Proteomic databases

PRIDEiB9M5A2

Interactioni

Protein-protein interaction databases

STRINGi316067.Geob_1498

Structurei

3D structure databases

ProteinModelPortaliB9M5A2
SMRiB9M5A2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000131425
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H0EIM

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 2 hits
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

B9M5A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKLELWQRY RKYLGVYPEI GMMLDLSRMN FPDDFFQLME PLMQQALEQM
60 70 80 90 100
AELERGGIAN GDEKRMVGHY WLRNPELAPT KEISSEIGFT LRAIKEFTEN
110 120 130 140 150
IHSGAISPPN GSRYTRMLII GIGGSALGPQ FVADALGSAK DKITPFFFDN
160 170 180 190 200
TDPDGMDLVL ARIGSYLKET LTIVISKSGG TKETRNGMLE AKKAYEDRGL
210 220 230 240 250
LFARQAVAVT GRDSELDRTA AAEGWLARFP MWDWIGGRTS VTSAVGLLPA
260 270 280 290 300
ALQGLDIDGL LEGARLCDMV TRIRETRNNP AALLALMWHY ATGGCGAKDM
310 320 330 340 350
VILPYKDRLL LFSRYLQQLI MESIGKEFDR NGTQANQGIA VYGNKGSTDQ
360 370 380 390 400
HAYVQQLREG INNFFVTFIE VLKDRNGRSI EVDPGVTSGD YLSGFFQGTR
410 420 430 440 450
EALYEKGRES ITITVDELSP RTIGVLIALY ERAVGFYASL VNINAYHQPG
460 470 480 490 500
VEAGKKAAGV VLEIQGKVLA HLQEKKGRGF TAEELAAAIG AEGEAEAIYR
510 520 530
ILLHAAANPD HSVVAEKGRT VFDKKFYHGG
Length:530
Mass (Da):58,481
Last modified:March 24, 2009 - v1
Checksum:i322E880B83F57169
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001390 Genomic DNA Translation: ACM19857.1
RefSeqiWP_012646586.1, NC_011979.1

Genome annotation databases

EnsemblBacteriaiACM19857; ACM19857; Geob_1498
KEGGigeo:Geob_1498

Similar proteinsi

Entry informationi

Entry nameiG6PI_GEODF
AccessioniPrimary (citable) accession number: B9M5A2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health