SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B9M3X6

- GCSPA_GEODF

UniProt

B9M3X6 - GCSPA_GEODF

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene
gcvPA, Geob_1259
Organism
Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciGSP316067:GHSV-1274-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1 (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein subunit 1
Glycine decarboxylase subunit 1
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Gene namesi
Name:gcvPA
Ordered Locus Names:Geob_1259
OrganismiGeobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Taxonomic identifieri316067 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000007721: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 442442Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotationPRO_1000147986Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity.

Protein-protein interaction databases

STRINGi316067.Geob_1259.

Structurei

3D structure databases

ProteinModelPortaliB9M3X6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

B9M3X6-1 [UniParc]FASTAAdd to Basket

« Hide

MSYCPNTPED IREMLAAIGK GSVEELFEPI HHTLRAKSFN LPAGISEQEL    50
LVKMQELAAC DRHLINFIGG GYYDHHIPAV VDHLSGRAEF YTAYTPYQPE 100
CSQGTLQALF EYQTAICRLT GMEVSNASLY DGGTALAEAA MMALRITGRN 150
RVVIDASVNP FARQIVATYL KNIGVEMVEI PTSSGSADRS ALTEALTGDV 200
AAVMVQNPNF FGSIEDLTAI SQAAHAKGAL LVTSVYPISL GLIKSPGEMG 250
ADIVVGDGQS LGNPLAFGGP SFGFIATTKK YIRNLPGRII GETIDKEGRR 300
GFVLTLQARE QHIKRHKATS NICSNQSLCA LRGLIFLASV GKEGMVELAN 350
LNRDKAEYAK ERLGSIRGVR VLNRGATFNE FTLELPKDAA DVVRTLMEKG 400
IAAGVPLGEY YAGMANCMVV TVTEKRSRGE IEALAEALEA SL 442
Length:442
Mass (Da):47,608
Last modified:March 24, 2009 - v1
Checksum:i619DCD2C3A8CD2D8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001390 Genomic DNA. Translation: ACM19619.1.
RefSeqiYP_002536720.1. NC_011979.1.

Genome annotation databases

EnsemblBacteriaiACM19619; ACM19619; Geob_1259.
GeneIDi7363082.
KEGGigeo:Geob_1259.
PATRICi22009036. VBIGeoSp137169_1290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001390 Genomic DNA. Translation: ACM19619.1 .
RefSeqi YP_002536720.1. NC_011979.1.

3D structure databases

ProteinModelPortali B9M3X6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316067.Geob_1259.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACM19619 ; ACM19619 ; Geob_1259 .
GeneIDi 7363082.
KEGGi geo:Geob_1259.
PATRICi 22009036. VBIGeoSp137169_1290.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OrthoDBi EOG6XWV3B.

Enzyme and pathway databases

BioCyci GSP316067:GHSV-1274-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 22248 / JCM 15807 / FRC-32.

Entry informationi

Entry nameiGCSPA_GEODF
AccessioniPrimary (citable) accession number: B9M3X6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi