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B9M2C3 (PGK_GEODF) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Geob_2898
OrganismGeobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32) [Complete proteome] [HAMAP]
Taxonomic identifier316067 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000192833

Regions

Nucleotide binding353 – 3564ATP By similarity
Region22 – 243Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1201Substrate By similarity
Binding site1531Substrate By similarity
Binding site2041ATP By similarity
Binding site3261ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B9M2C3 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 476022FA000B11DD

FASTA39942,766
        10         20         30         40         50         60 
MSILYIDEIK DLREKLVFIR VDFNVPQDDN GNITEDTRIV GAVPTIKYAI ENGAKVILAS 

        70         80         90        100        110        120 
HLGRPKGEKK PKYTMAPAAR RLSELLGKEV KQATDCFGPD VDAMVAALQP GDVLMLENVR 

       130        140        150        160        170        180 
FYPGEEKNDP DFACKLANGC EIYVNDAFAV SHRAHASVHA ITKCIPVIAA GFLMKNEMTF 

       190        200        210        220        230        240 
FEKAMTRPVR PLAAILGGAK VSGKLEVLET LVGKVDIIII GGGMAFTFLK ARGLSVGKSL 

       250        260        270        280        290        300 
VEDDLIDTAK RILDNAAKRG IEFLLPEDCV VADRFAADAD CKTVSVNDIP SEWMALDVGP 

       310        320        330        340        350        360 
ASTARFSDAL KEANTVIWNG PMGVFEMDRF AKGTFAIADV VAGLKNATTI IGGGDTDSAV 

       370        380        390 
RKAGVADKVS YISTGGGAFL ELLEGKKLPG VEVLEQSGK 

« Hide

References

[1]"Complete sequence of Geobacter sp. FRC-32."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Kostka J., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 22248 / JCM 15807 / FRC-32.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001390 Genomic DNA. Translation: ACM21241.1.
RefSeqYP_002538342.1. NC_011979.1.

3D structure databases

ProteinModelPortalB9M2C3.
SMRB9M2C3. Positions 1-396.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316067.Geob_2898.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM21241; ACM21241; Geob_2898.
GeneID7362210.
KEGGgeo:Geob_2898.
PATRIC22012479. VBIGeoSp137169_2994.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycGSP316067:GHSV-2933-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_GEODF
AccessionPrimary (citable) accession number: B9M2C3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways