SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B9LTZ6

- B9LTZ6_HALLT

UniProt

B9LTZ6 - B9LTZ6_HALLT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Argininosuccinate synthase
Gene
argG, Hlac_2619
Organism
Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei84 – 841Citrulline By similarityUniRule annotation
Binding sitei114 – 1141ATP; via amide nitrogen By similarityUniRule annotation
Binding sitei116 – 1161Aspartate By similarityUniRule annotation
Binding sitei120 – 1201Aspartate By similarityUniRule annotation
Binding sitei120 – 1201Citrulline By similarityUniRule annotation
Binding sitei121 – 1211Aspartate By similarityUniRule annotation
Binding sitei124 – 1241Citrulline By similarityUniRule annotation
Binding sitei170 – 1701Citrulline By similarityUniRule annotation
Binding sitei251 – 2511Citrulline By similarityUniRule annotation
Binding sitei263 – 2631Citrulline By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 159ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHLAC416348:GIWW-2674-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthaseUniRule annotation (EC:6.3.4.5UniRule annotation)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argGUniRule annotation
Ordered Locus Names:Hlac_2619Imported
OrganismiHalorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)Imported
Taxonomic identifieri416348 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalorubrum
ProteomesiUP000000740: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi416348.Hlac_2619.

Structurei

3D structure databases

ProteinModelPortaliB9LTZ6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9LTZ6-1 [UniParc]FASTAAdd to Basket

« Hide

MATVALAFSG GLDTTVCVPL LKEEYGYDEV IGVNVDVGQP TEEFDEAEET    50
ADALGLDLHV VDAKEEFADL CYDAVKTNAT YQGYPLGTAL ARPVIAEAIL 100
GVAEEQGCDA IAHGCTGKGN DQLRFEAVWR GSDLEVIAPV RELGLTREWE 150
IDYAAEKDLP VEAGDGGVWS IDENIWSRAV EGGKLEDPSY EPPEDIYEWT 200
AGPEGETTIE VTFEEGVPVA IDGEAMDPVP LIQYLNKYAG GYGIGRTDVM 250
EDRMLGLKVR ENYEHPAATV LLTAHQALED LVLTKNERSF KKGIEQEWSE 300
KAYQGLVFAP VVDALDAFVD ETQDVVTGTA TVKVSGGNCR VVARDSEYAV 350
YSEEMASFNT EDVAGIAQED ATGVAKYHGL QERLANDVKA GVEKPELATD 400
GSGAADEIDD EN 412
Length:412
Mass (Da):44,490
Last modified:March 24, 2009 - v1
Checksum:i02A37D364493C342
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001365 Genomic DNA. Translation: ACM58190.1.
RefSeqiYP_002567260.1. NC_012029.1.

Genome annotation databases

EnsemblBacteriaiACM58190; ACM58190; Hlac_2619.
GeneIDi7399845.
KEGGihla:Hlac_2619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001365 Genomic DNA. Translation: ACM58190.1 .
RefSeqi YP_002567260.1. NC_012029.1.

3D structure databases

ProteinModelPortali B9LTZ6.
ModBasei Search...

Protein-protein interaction databases

STRINGi 416348.Hlac_2619.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACM58190 ; ACM58190 ; Hlac_2619 .
GeneIDi 7399845.
KEGGi hla:Hlac_2619.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci HLAC416348:GIWW-2674-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N.
    , Anderson I., DasSarma S., Cavicchioli R., Richardson P.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34.

Entry informationi

Entry nameiB9LTZ6_HALLT
AccessioniPrimary (citable) accession number: B9LTZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi