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B9LSK0 (PGK_HALLT) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Hlac_2372
OrganismHalorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) [Complete proteome] [HAMAP]
Taxonomic identifier416348 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalorubrum

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 407407Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000192861

Regions

Nucleotide binding358 – 3614ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1161Substrate By similarity
Binding site1561Substrate By similarity
Binding site3321ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B9LSK0 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: B21A7D906C9EDFEA

FASTA40743,823
        10         20         30         40         50         60 
MAAFDTIDDL PADSRVLVRL DLNSPIEDGK PQDNRRFERH AETVRELADA GHRVVLMAHQ 

        70         80         90        100        110        120 
GRPGRDDFTS LSGHADILAD HVGRDVAFVA DTFGDEALDA IDALGAGEVL LLENTRMCDD 

       130        140        150        160        170        180 
ELPEADPEEK AETEFVQTLA PQFDAYVNDA YSAAHRKHAS LVGFPLVLPA YAGRVMETEY 

       190        200        210        220        230        240 
EANTAIATRE FDGPVTMVVG GTKATDVIGV MDALDDRVDR FLLGGVAGEL FLRAAGHPVG 

       250        260        270        280        290        300 
HDLEGTDLFD EQWEENRELI ESVLDERGDA IRLATDLAYE GPDGDRAEVA VDDIDEKTDG 

       310        320        330        340        350        360 
YLDVGSETIA AYEPPIHESD AVFVKGALGV FEDERFADGT VGVLEAIAET DCFSVVGGGD 

       370        380        390        400 
TSRAIEMYGL DEDDFSHVSI AGGAYIRALT GEPLPAVEVL EAAAGRQ 

« Hide

References

[1]"Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Anderson I., DasSarma S., Cavicchioli R., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001365 Genomic DNA. Translation: ACM57947.1.
RefSeqYP_002567017.1. NC_012029.1.

3D structure databases

ProteinModelPortalB9LSK0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416348.Hlac_2372.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM57947; ACM57947; Hlac_2372.
GeneID7401990.
KEGGhla:Hlac_2372.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAAGHPVGK.

Enzyme and pathway databases

BioCycHLAC416348:GIWW-2425-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_HALLT
AccessionPrimary (citable) accession number: B9LSK0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways