Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B9LRF1 (SYR_HALLT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Hlac_0169
OrganismHalorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) [Complete proteome] [HAMAP]
Taxonomic identifier416348 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalorubrum

Protein attributes

Sequence length602 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 602602Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198942

Regions

Motif124 – 13411"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B9LRF1 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 618E820646F93457

FASTA60266,200
        10         20         30         40         50         60 
MFRQFRSEVA DALGDALASL DLPTDDLGIE RPPDDMDATL ASSVAFRLAG EVGDAPPNVA 

        70         80         90        100        110        120 
ATVADAVDVD GYDYLAAVDT AGPYVNFHPG ERYFVDTLDA SAVDSGYGAL PDRDTSVVVE 

       130        140        150        160        170        180 
HTSANPTGPV HVGRARNPIV GDAVANLLEY AGYDVDRHYY VNDAGRQMAV FTWAYERFDE 

       190        200        210        220        230        240 
SDLAGEPARA RAEYDLVRYY RKGNAYLEEA DPEAVEAAEE EIAAILQGLE AGDEETYERV 

       250        260        270        280        290        300 
GEVVDTVLGG MKECLARLPA EFDEFVKETR FMRDGSTDDI AARLKETDHA VYEEDAWQLE 

       310        320        330        340        350        360 
LDDWGIDKNL VFLRSDDTSL YTTRDLAHHE WKFDNYDRAV TVLGEDHKLQ ADQLDATLEL 

       370        380        390        400        410        420 
LGNDIDRLGH VIYSYVNLPD GKMSTRRGTG VMLDDLLDEA IDRAREAVET RMDDRIRDDD 

       430        440        450        460        470        480 
LTEEDVERIA HEVGIGAVRY DIVSKQPAKA ITFEWEDALD FEGQSAPFVQ YVHARCCGIL 

       490        500        510        520        530        540 
DEAADAGIEV PGVTADSEGV VDVGALDVDA TVFETDAARD LLREVARFPA AIESAADDLE 

       550        560        570        580        590        600 
PHTIATFTRE FADAYNAFYR ECPVVTSDDE ELRAARVALV AAAKHTMANA LDVLGVEAPE 


SM 

« Hide

References

[1]"Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Anderson I., DasSarma S., Cavicchioli R., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001365 Genomic DNA. Translation: ACM55774.1.
RefSeqYP_002564844.1. NC_012029.1.

3D structure databases

ProteinModelPortalB9LRF1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416348.Hlac_0169.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM55774; ACM55774; Hlac_0169.
GeneID7402098.
KEGGhla:Hlac_0169.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMAMEHMGFG.

Enzyme and pathway databases

BioCycHLAC416348:GIWW-179-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_HALLT
AccessionPrimary (citable) accession number: B9LRF1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries