B9LQ87 (B9LQ87_HALLT) Unreviewed, UniProtKB/TrEMBL
Last modified
January 25, 2012.
Version 20.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Delta-aminolevulinic acid dehydratase RuleBase RU000515 EC=4.2.1.24 RuleBase RU000515 | ||
| Gene names |
| ||
| Organism | Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 416348 [NCBI] | ||
| Taxonomic lineage | Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halorubrum |
Protein attributes
| Sequence length | 326 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515 |
| Subunit structure | Homooctamer By similarity. PIRSR PIRSR001415-3 RuleBase RU000515 |
| Sequence similarities | Belongs to the ALADH family. RuleBase RU004161 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Porphyrin biosynthesis RuleBase RU000515 |
| Ligand | Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5 Zinc PIRSR PIRSR001415-3 |
| Molecular function | Lyase RuleBase RU000515 EMBL ACM55621.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 199 | 1 | Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1 | ||||||
| Active site | 252 | 1 | Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1 | ||||||
| Metal binding | 117 | 1 | Zinc; catalytic By similarity PIRSR PIRSR001415-3 | ||||||
| Metal binding | 119 | 1 | Zinc; catalytic By similarity PIRSR PIRSR001415-3 | ||||||
| Metal binding | 127 | 1 | Zinc; catalytic By similarity PIRSR PIRSR001415-3 | ||||||
| Metal binding | 237 | 1 | Magnesium By similarity PIRSR PIRSR001415-5 | ||||||
| Binding site | 209 | 1 | Substrate 1 By similarity PIRSR PIRSR001415-2 | ||||||
| Binding site | 221 | 1 | Substrate 1 By similarity PIRSR PIRSR001415-2 | ||||||
| Binding site | 278 | 1 | Substrate 2 By similarity PIRSR PIRSR001415-2 | ||||||
| Binding site | 317 | 1 | Substrate 2 By similarity PIRSR PIRSR001415-2 | ||||||
Sequences
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References
| [1] | "Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. Richardson P.Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001365 Genomic DNA. Translation: ACM55621.1. |
| RefSeq | YP_002564691.1. NC_012029.1. |
3D structure databases | |
| ProteinModelPortal | B9LQ87. |
| SMR | B9LQ87. Positions 3-325. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | B9LQ87. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 7401363. |
| GenomeReviews | Gene locus Hlac_0015 in contig CP001365_GR. |
| KEGG | hla:Hlac_0015. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| OMA | ADLCFCE. |
| ProtClustDB | PRK09283. |
Family and domain databases | |
| InterPro | IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| KO | K01698. |
| PANTHER | PTHR11458. AlaD_dehydratase. 1 hit. |
| Pfam | PF00490. ALAD. 1 hit. [Graphical view] |
| PIRSF | PIRSF001415. Porphbilin_synth. 1 hit. |
| PRINTS | PR00144. DALDHYDRTASE. |
| SMART | SM01004. ALAD. 1 hit. [Graphical view] |
| PROSITE | PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | B9LQ87_HALLT | ||||||||
| Accession | Primary (citable) accession number: B9LQ87 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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