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B9LP84 (PYRF_HALLT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:Hlac_1586
OrganismHalorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) [Complete proteome] [HAMAP]
Taxonomic identifier416348 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalorubrum

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000164749

Sites

Active site931Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
B9LP84 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: C8412DCC9224E76D

FASTA27629,838
        10         20         30         40         50         60 
MSFFETLADR IEATDSVVSV GLDPDPNRLP EFLANADLPR WAFNRRIIDA THEHAACYKP 

        70         80         90        100        110        120 
NAAFYEDADG WRALEETIAY AHGKDVPVLL DAKRADIGNT TRQYAAALDR ADAITVNPYL 

       130        140        150        160        170        180 
GRDSLQPFLD REEKGVFVLC RTSNPGGSDL QDLELASGEP LYERVAALAD VWNGNDNVGL 

       190        200        210        220        230        240 
VVGATAPEEL AEVREIVPEI PFLVPGVGAQ GGDAEAAVEH GLADRPDAAV DVGLVNSSRG 

       250        260        270 
IIFAGEESSR PDDEATYFGA AGDAAKRLKK RLNQYR 

« Hide

References

[1]"Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Anderson I., DasSarma S., Cavicchioli R., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001365 Genomic DNA. Translation: ACM57172.1.
RefSeqYP_002566242.1. NC_012029.1.

3D structure databases

ProteinModelPortalB9LP84.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416348.Hlac_1586.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM57172; ACM57172; Hlac_1586.
GeneID7399534.
KEGGhla:Hlac_1586.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMACRTSNAG.

Enzyme and pathway databases

BioCycHLAC416348:GIWW-1621-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_HALLT
AccessionPrimary (citable) accession number: B9LP84
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways