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B9LMX8 (B9LMX8_HALLT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP-Rule MF_00186
EC=2.7.1.30 HAMAP-Rule MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP-Rule MF_00186
Glycerokinase HAMAP-Rule MF_00186
Gene names
Name:glpK HAMAP-Rule MF_00186
Ordered Locus Names:Hlac_1122 EMBL ACM56716.1
OrganismHalorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) [Complete proteome] [HAMAP] EMBL ACM56716.1
Taxonomic identifier416348 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halorubrum ›

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP-Rule MF_00186

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP-Rule MF_00186

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP-Rule MF_00186

Sequence similarities

Belongs to the FGGY kinase family. HAMAP-Rule MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding420 – 4245ATP By similarity HAMAP-Rule MF_00186

Sites

Binding site121Substrate By similarity HAMAP-Rule MF_00186
Binding site161ATP By similarity HAMAP-Rule MF_00186
Binding site821Substrate By similarity HAMAP-Rule MF_00186
Binding site1341Substrate By similarity HAMAP-Rule MF_00186
Binding site2541Substrate By similarity HAMAP-Rule MF_00186
Binding site2761ATP By similarity HAMAP-Rule MF_00186
Binding site3201ATP; via carbonyl oxygen By similarity HAMAP-Rule MF_00186

Sequences

Sequence LengthMass (Da)Tools
B9LMX8 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 7E895D1C49649093

FASTA51356,951
        10         20         30         40         50         60 
MTQYVGAIDQ GTTGTRFMVF DHGGQVVANA YEQHEQIYPN PGWVEHDPIE IWENTQQVVL 

        70         80         90        100        110        120 
DGLADAGLEA NQLDAIGITN QRETTIVWDR ETGRPVHNAL VWQDRRTTDR VEELQEADKV 

       130        140        150        160        170        180 
EDIREKTGLE ADAYFSATKT EWILDNAEPL KMQSSRGGDL RDRAREGELV MGTIDSWLIY 

       190        200        210        220        230        240 
NLTGNHITDV TNASRTMLYN IRDLEWDDEL LEEFDVPKEM VPEVRPSSDE DYYGHTDADG 

       250        260        270        280        290        300 
FLGEEVPVAG ALGDQQAALF GQTCFDEGDA KNTYGTGSFY LMNTGNEAVK SDHGLLTTIG 

       310        320        330        340        350        360 
FQMSGEPVQY ALEGSIFITG AAIEWLEDVD LINNAAQTAE LARSVDSTDG VYMVPAFTGL 

       370        380        390        400        410        420 
GAPHWDGRAR GTIVGMTRGT GKEHIVRATL ESIAYQTRDV AEAMEADSGV ETTSLRVDGG 

       430        440        450        460        470        480 
AVKNNFLCQL QSDIIQTEIA RPEVDETTAL GSAYAAGLAV GYWDTVDELR DNWQIDREFT 

       490        500        510 
PEKGQAEVDK LYSRWDDAVE RSLNWAQDDE EDE

« Hide

References

[1]"Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Anderson I., DasSarma S., Cavicchioli R., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001365 Genomic DNA. Translation: ACM56716.1.
RefSeqYP_002565786.1. NC_012029.1.

3D structure databases

ProteinModelPortalB9LMX8.
ModBaseSearch...

Protein-protein interaction databases

STRING416348.Hlac_1122.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM56716; ACM56716; Hlac_1122.
GeneID7400931.
KEGGhla:Hlac_1122.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHOG000222134.
KOK00864.
OMAPDGGLHV.
ProtClustDBCLSK511574.

Enzyme and pathway databases

BioCycHLAC416348:GIWW-1147-MONOMER.
UniPathwayUPA00618; UER00672.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
InterProIPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
PANTHERPTHR10196:SF9. PTHR10196:SF9. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. glycerol_kin. 1 hit.
PROSITEPS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9LMX8_HALLT
AccessionPrimary (citable) accession number: B9LMX8
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info