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B9LMX0 (AROC_HALLT) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Hlac_1114
OrganismHalorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) [Complete proteome] [HAMAP]
Taxonomic identifier416348 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halorubrum

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Chorismate synthase HAMAP MF_00300
PRO_1000132775

Sequences

Sequence LengthMass (Da)Tools
B9LMX0 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: FBCEF1EB9381982D

FASTA39542,662
        10         20         30         40         50         60 
MNGNRFGRLF QVTTYGESHG EAMGVTVSGV PAGVELDEEA IQAQLDRRKP GQSMITTSRG 

        70         80         90        100        110        120 
EPDEVVVNSG VQDGYTTGTP IGMVIQNKDA RSGKYEPYVT APRPSHGDYT YSAKFGTRNW 

       130        140        150        160        170        180 
GGGGRSSARE TVNWVAAGAV AEQVLDASEY DVEIKAHVNQ IGDVEADDVS FEQILDHSEE 

       190        200        210        220        230        240 
NDVRCADPEA AAEMQELIER YQEAGDSIGG SIYFECRGVP RGLGAPRFDG FPSRLGQAMF 

       250        260        270        280        290        300 
SIPATTGVEF GLGKDAVNVT GSERNEDWTF DDGESFDHVE SEEGDPVPVG NDHGGLQGGI 

       310        320        330        340        350        360 
TTGEPIYGEA TWHAPTSIPK KQRSADWETG EEKDVQVVGR HDPVLPPRAV PVVEAMLYCT 

       370        380        390 
VLDFMLLAGR INPDRVDGNP GQYDTDYHPS SPDND

« Hide

References

[1]"Complete sequence of chromosome1 of Halorubrum lacusprofundi ATCC 49239."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Anderson I., DasSarma S., Cavicchioli R., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001365 Genomic DNA. Translation: ACM56708.1.
RefSeqYP_002565778.1. NC_012029.1.

3D structure databases

ProteinModelPortalB9LMX0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9LMX0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7400923.
GenomeReviewsGene locus Hlac_1114 in contig CP001365_GR.
KEGGhla:Hlac_1114.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMASRFTTQR.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_HALLT
AccessionPrimary (citable) accession number: B9LMX0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: November 16, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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