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B9LKR2 (B9LKR2_CHLSY) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
Short name=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF HAMAP MF_01840
Ordered Locus Names:Chy400_2799
OrganismChloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl) [Complete proteome] [HAMAP] EMBL ACM54187.1
Taxonomic identifier480224 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; bacteriochlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B9LKR2 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 632DB49BED97AD01

FASTA37545,052
        10         20         30         40         50         60 
MFWINPLMME MPGEFSRTTR HALKEAILSP RFYTTDFKAI DRLEIDRNGL RDEFDWIRDE 

        70         80         90        100        110        120 
FAYDYNRTHF RRTDEFLQDF DDMPERDSFI DFLERSCTAE FSGCLLYAEM VKHLHDPTLR 

       130        140        150        160        170        180 
AIFKYMSRDE GRHAGFLNRT MADLNVALDL TVLQKRKKYT YFQPKFIFYS VYLSEKIGYS 

       190        200        210        220        230        240 
RYITIYRHLE RNPQYCIHPI FKWFEQWCND EYRHGEFFAL LMRSQPEMLE GVNRRWIRFF 

       250        260        270        280        290        300 
LLAVYATMYL NDARRSNFYA ALGLDWRDYD QTVIRLCNDI ATQVYPETMN LDDPRFFAYM 

       310        320        330        340        350        360 
DKLVEYDRAL RALESRKDPI AMAHSTRLKA AIALRLLAIY RLPTRKTTEA IRWKGLPGFP 

       370 
NYPGPNRPQR VVAAD

« Hide

References

[1]"Complete sequence of Chloroflexus sp. Y-400-fl."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Kiss H., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Bryant D.A., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29364 / DSM 637 / Y-400-fl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001364 Genomic DNA. Translation: ACM54187.1.
RefSeqYP_002570513.1. NC_012032.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9LKR2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7404270.
GenomeReviewsGene locus Chy400_2799 in contig CP001364_GR.
KEGGchl:Chy400_2799.
PATRIC21425241. VBIChlSp61043_2900.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAHGDFFDA.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB9LKR2_CHLSY
AccessionPrimary (citable) accession number: B9LKR2
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info