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B9LJ01 (B9LJ01_CHLSY) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Ordered Locus Names:Chy400_0526
OrganismChloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl) [Complete proteome] [HAMAP] EMBL ACM51963.1
Taxonomic identifier480224 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. HAMAP MF_01405 SAAS SAAS020922

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. HAMAP MF_01405 SAAS SAAS020922

Subunit structure

Homodimer By similarity. HAMAP MF_01405 SAAS SAAS020922

Sequence similarities

Belongs to the HAM1 NTPase family. HAMAP MF_01405

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region8 – 136Substrate binding By similarity HAMAP MF_01405
Region70 – 712Substrate binding By similarity HAMAP MF_01405

Sites

Metal binding411Magnesium or manganese By similarity HAMAP MF_01405
Metal binding701Magnesium or manganese By similarity HAMAP MF_01405
Binding site1541Substrate By similarity HAMAP MF_01405
Binding site1741Substrate By similarity HAMAP MF_01405
Binding site1801Substrate By similarity HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
B9LJ01 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: F95F1D06008F952C

FASTA20021,704
        10         20         30         40         50         60 
MRELLIATHN PGKLREFAAI FADLNLRLYS LADVGIQETI EETGQTFAEN ARLKAEGYLA 

        70         80         90        100        110        120 
LSGLPTLADD SGLEVAALGG APGVYSARYG GLSGPAQLQY LLDQMRDIPW HQRLARFVCV 

       130        140        150        160        170        180 
IALAHPDHPT ELVEGTLPGV IEFAPRGSGG FGYDPLFYVL DEDATLAELS AERKNQISHR 

       190        200 
AQAARAAREV LARWQRSSGS

« Hide

References

[1]"Complete sequence of Chloroflexus sp. Y-400-fl."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Kiss H., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Bryant D.A., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29364 / DSM 637 / Y-400-fl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001364 Genomic DNA. Translation: ACM51963.1.
RefSeqYP_002568288.1. NC_012032.1.

3D structure databases

ProteinModelPortalB9LJ01.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9LJ01.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7403490.
GenomeReviewsGene locus Chy400_0526 in contig CP001364_GR.
KEGGchl:Chy400_0526.
PATRIC21420462. VBIChlSp61043_0548.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGVYTADW.
ProtClustDBCLSK974075.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB9LJ01_CHLSY
AccessionPrimary (citable) accession number: B9LJ01
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info