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B9LE79 (B9LE79_CHLSY) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823
Ordered Locus Names:Chy400_1786
OrganismChloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl) [Complete proteome] [HAMAP] EMBL ACM53195.1
Taxonomic identifier480224 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823

Subcellular location

Cytoplasm By similarity HAMAP MF_00823.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
B9LE79 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 0C0BE3846CA2AD31

FASTA28231,306
        10         20         30         40         50         60 
MEETAIPQSL TPWDRVQLAR HPQRPHTLDY IAALCEDFVE LHGDRRFGDD PAMVGGMATF 

        70         80         90        100        110        120 
AGQTVMVIGH QKGNDTRENM RRNFGMPHPE GYRKAQRLMR HAEKFGLPVI CFVDTPAADP 

       130        140        150        160        170        180 
TKSSEERGQA NAIAESIMLM TTLRVPSIAV VIGEGGSGGA LAISVADRIL MQENAIYSVA 

       190        200        210        220        230        240 
PPEAAASILW RDAAKAPEAA RALKLTAADL YDLRIIDEVI PEPPGGAHAD RLTAITTVGE 

       250        260        270        280 
RLRVHLADLQ QRDIDTLLRE RYRKYRSMGQ YQEQQMDFFG RM

« Hide

References

[1]"Complete sequence of Chloroflexus sp. Y-400-fl."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Kiss H., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Bryant D.A., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29364 / DSM 637 / Y-400-fl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001364 Genomic DNA. Translation: ACM53195.1.
RefSeqYP_002569521.1. NC_012032.1.

3D structure databases

ProteinModelPortalB9LE79.
SMRB9LE79. Positions 7-273.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9LE79.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7403316.
GenomeReviewsGene locus Chy400_1786 in contig CP001364_GR.
KEGGchl:Chy400_1786.
PATRIC21423133. VBIChlSp61043_1866.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGRDTKDN.
ProtClustDBCLSK972928.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9LE79_CHLSY
AccessionPrimary (citable) accession number: B9LE79
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info