B9LCV3 (FABZ_CHLSY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	Chy400_1555

Organism

Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl) [Complete proteome] [HAMAP]

Taxonomic identifier

480224 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis By similarity. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 144	144	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_1000134695
Sites
	Active site	48	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B9LCV3 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 8760C4FF606D8C17	FASTA	144	15,603
	10 20 30 40 50 60 MLSIQEIMAL IPHRYPFLLV DRIMELEPGV RAVGEKLVSA NEPYFQGHFP GNPIMPGVLI 70 80 90 100 110 120 LEALAQTGAV AALSAPENAG KLVLFAGIDG ARFKRVVRPG DTLRLEVQLE KMRRGVGKGQ 130 140 ARATVADQLA CEAELLFALT DPSR

References

[1]

"Complete sequence of Chloroflexus sp. Y-400-fl." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Kiss H., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. , Ovchinnikova G., Bryant D.A., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29364 / DSM 637 / Y-400-fl.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001364 Genomic DNA. Translation: ACM52973.1.
RefSeq	YP_002569299.1. NC_012032.1.
3D structure databases
ProteinModelPortal	B9LCV3.
ModBase	Search...
Protein-protein interaction databases
STRING	B9LCV3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7402628.
GenomeReviews	Gene locus Chy400_1555 in contig CP001364_GR.
KEGG	chl:Chy400_1555.
PATRIC	21422619. VBIChlSp61043_1609.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	KERRGVA.
ProtClustDB	PRK00006.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_CHLSY

Accession

Primary (citable) accession number: B9LCV3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program