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B9L8W1 (B9L8W1_NAUPA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate--tRNA ligase 2 HAMAP MF_00022
EC=6.1.1.17 HAMAP MF_00022
Alternative name(s):
Glutamyl-tRNA synthetase 2 HAMAP MF_00022
Gene names
Name:gltX EMBL ACM92650.1
Synonyms:gltX2 HAMAP MF_00022
Ordered Locus Names:NAMH_0657
OrganismNautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH) [Complete proteome] [HAMAP]
Taxonomic identifier598659 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Nautiliales › Nautiliaceae › Nautilia

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity. HAMAP MF_00022

Catalytic activity

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). HAMAP MF_00022

Subunit structure

Monomer By similarity. HAMAP MF_00022

Subcellular location

Cytoplasm By similarity HAMAP MF_00022.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00022 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif6 – 1611"HIGH" region By similarity HAMAP MF_00022
Motif238 – 2425"KMSKS" region By similarity HAMAP MF_00022

Sites

Binding site2411ATP By similarity HAMAP MF_00022

Sequences

Sequence LengthMass (Da)Tools
B9L8W1 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: CC304C67ED4DE1A6

FASTA43451,260
        10         20         30         40         50         60 
MLRFAPSPTG DMHIGNLRVA IFNYIIAKQK NEKLLIRIED TDKERNIEGK DKEILDILHL 

        70         80         90        100        110        120 
FGIEYDNVVY QSANLHMHQQ MAKKLLDDKK AFVCFCDEEE INFQREKAKI EKRPYRYSGK 

       130        140        150        160        170        180 
CENLTSTEIR KYLDKKTPFV VRLKKPEKNI KFNDLIKGDF DFSPFDIDSF IIMRKDFTPT 

       190        200        210        220        230        240 
YNFACAIDDM LYDISLVIRG EDHLSNTPKQ IAIRDALGYD KEIKYAHLPI ILNEEGKKMS 

       250        260        270        280        290        300 
KRDNASSVKW LLEEGFLPEA IANYLILLGN SFEKEIFTLK EAIEFFDITK ISRAPAKFDL 

       310        320        330        340        350        360 
GKLRFINKEH MKKIEKLTRY IGYHEEYEPL AKLYLDEVST IKELKEKLDN IFTKKEFDEF 

       370        380        390        400        410        420 
NDEIEILKKE ILDNEFEDNY NDFKNRIMNN TGLKGKKLFM PLRMLMVGSK QGPEIKDLYA 

       430 
IMKPYLKMII KEYR

« Hide

References

[1]"Adaptations to submarine hydrothermal environments exemplified by the genome of Nautilia profundicola."
Campbell B.J., Smith J.L., Hanson T.E., Klotz M.G., Stein L.Y., Lee C.K., Wu D., Robinson J.M., Khouri H.M., Eisen J.A., Cary S.C.
PLoS Genet. 5:E1000362-E1000362(2009) [PubMed: 19197347] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001279 Genomic DNA. Translation: ACM92650.1.
RefSeqYP_002607069.1. NC_012115.1.

3D structure databases

ProteinModelPortalB9L8W1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9L8W1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7503982.
GenomeReviewsGene locus NAMH_0657 in contig CP001279_GR.
KEGGnam:NAMH_0657.
PATRIC22676033. VBINauPro131435_0630.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMASVKWLLN.
ProtClustDBPRK12410.

Family and domain databases

HAMAPMF_00022_B. Glu_tRNA_synth_B.
[Tree]
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-synth_Ib_bac/mito.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit.
G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
G3DSA:1.10.10.350. tRNA_synt_bd. 1 hit.
KOK01885.
PANTHERPTHR10119. Glu_tRNA-synt_1c. 1 hit.
PTHR10119:SF1. PTHR10119:SF1. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00464. GltX_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9L8W1_NAUPA
AccessionPrimary (citable) accession number: B9L8W1
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info