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B9L7J6 (B9L7J6_NAUPA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta HAMAP MF_01321
Short name=RNAP subunit beta HAMAP MF_01321
EC=2.7.7.6 HAMAP MF_01321
Alternative name(s):
RNA polymerase subunit beta HAMAP MF_01321
Transcriptase subunit beta HAMAP MF_01321
Gene names
Name:rpoB HAMAP MF_01321 EMBL ACM93318.1
Ordered Locus Names:NAMH_0180
OrganismNautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH) [Complete proteome] [HAMAP]
Taxonomic identifier598659 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Nautiliales › Nautiliaceae › Nautilia

Protein attributes

Sequence length1379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP MF_01321 RuleBase RU000432

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_01321

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity. HAMAP MF_01321 RuleBase RU000433

Sequence similarities

Belongs to the RNA polymerase beta chain family. HAMAP MF_01321 RuleBase RU000434

Sequences

Sequence LengthMass (Da)Tools
B9L7J6 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: F28B312A53DBB58D

FASTA1,379156,882
        10         20         30         40         50         60 
MLNQLKSANR LRLDFSKIPQ ILDIPNLLHL QQNSFQDFIN LKEPEKSGIH KVFKSMFPIT 

        70         80         90        100        110        120 
DAQNRITLEY AGIEFKKPKY TVRECMEKGL TYSIPIRIKI RLIVHERDEK TGEKIGIKDI 

       130        140        150        160        170        180 
KEQTLYIRDI PLMTERTSFI INGVERVIVN QLHRSPGVIF KQEEAQNSNK LLYSAQIIPD 

       190        200        210        220        230        240 
RGSWVYFEYD VKDVLYVRVN KRRKVPVTIL LRAMDYSKED ILRMFYPIVD IKIQDNKFLM 

       250        260        270        280        290        300 
STKALQSGKL DYDLKDPDGN IILAAGKRLS DRKLKKIQEE LEYVEYPIEV LLDRHLAEPI 

       310        320        330        340        350        360 
YDPVTGEVLF DTLTVLNEVK LKKIIESQIE DFKIVNDLAE GVDDSILRAF HQDIETLKIL 

       370        380        390        400        410        420 
RQVEGIENEN DLARIRIYKV MRPGEPATPQ TAKELFEKLF FDPERYDLTK VGRMKMNHKL 

       430        440        450        460        470        480 
GLNVPDDVTV LTYQDIIKTI QYLIGVKNGV GQIDDRDHLG NRRIRSIGEL LANRLQDGLA 

       490        500        510        520        530        540 
KMQKTIRDKM TTVTNVNDLL PMDLVNTKLV TTTILDFFAT GQLSQFMDQT NPLSEVAHKR 

       550        560        570        580        590        600 
RLSALGEGGV TRERAGFEIR DVHPSHYGRI CPIETPEGQN IGLVNTLSTY AKVNEFGFIE 

       610        620        630        640        650        660 
APYRVVKDGR VTDEVVYLTA TQEEEKTIAP ASVKIDEETG EILDDLIEAR KDGEIILVDK 

       670        680        690        700        710        720 
KEVDLYDLNP KMIVGVGASL IPFLEHDDAN RALMGSNMQR QGVPLLRSEA PMVGTGMEKY 

       730        740        750        760        770        780 
VARDAWQIVK AKRGGKVIKV DAKNIYILGE DENGAYIDHY GLEKYLRTNQ NTCFDQRPIV 

       790        800        810        820        830        840 
KEGDVVKAGD VIADGPNMDN GELGVGKNVM VAFMPWNGYN FEDAIVLSER IIKDDVYTSV 

       850        860        870        880        890        900 
HIYEEVCEVR ELKHGLEEIT ADIPGVKPEY LTHLDESGII KIGTYVKPGM ILVGKISPKG 

       910        920        930        940        950        960 
DVKPTPEERL LKSIFGDKSG HVVNSSLYAP ASMEGVVIDV KVYTKKGYEL DERAKAAYDE 

       970        980        990       1000       1010       1020 
EKAKIEEIYK NQLSIIDKEE VLALANLLSS KPLIKDVELN GKTYKAGEKL PKEELVNINK 

      1030       1040       1050       1060       1070       1080 
FLLLSLVEYF DDATVQEFEN IKAKYLNEKD NIRKEYDEKL EVLERDDILP NGVAKMVKVY 

      1090       1100       1110       1120       1130       1140 
IANKRKIKVG DKMAGRHGNK GIVSIIVPQE DMPYMEDGRT VDVVLNPLGV PSRMNIGQIL 

      1150       1160       1170       1180       1190       1200 
EVHLGLVGKN LGRQIEEILK EKQNDMMDKL RNKMKEIVEV AHFGEHYKDF LDSLTNEELL 

      1210       1220       1230       1240       1250       1260 
KYAQDWAKGV KFATPVFEGV NEEEFKKLFE LAGIPEDGKT QLYDGRTGEP IKERVNVGYM 

      1270       1280       1290       1300       1310       1320 
YMLKLHHLVD DKVHARSIGP YSLITQQPVG GKALFGGQRF GEMEVWALEA YGAAYNLKEM 

      1330       1340       1350       1360       1370 
LTTKSDDVEG RNKAYRALTR GENVPIEGLS ETFFVLSKEL RALGLDLEFY KKEEDNEEI

« Hide

References

[1]"Adaptations to submarine hydrothermal environments exemplified by the genome of Nautilia profundicola."
Campbell B.J., Smith J.L., Hanson T.E., Klotz M.G., Stein L.Y., Lee C.K., Wu D., Robinson J.M., Khouri H.M., Eisen J.A., Cary S.C.
PLoS Genet. 5:E1000362-E1000362(2009) [PubMed: 19197347] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001279 Genomic DNA. Translation: ACM93318.1.
RefSeqYP_002606604.1. NC_012115.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9L7J6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7505271.
GenomeReviewsGene locus NAMH_0180 in contig CP001279_GR.
KEGGnam:NAMH_0180.
PATRIC22675073. VBINauPro131435_0162.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVDARDTK.
ProtClustDBPRK00405.

Family and domain databases

HAMAPMF_01321. RNApol_bact_RpoB.
[Tree]
InterProIPR010243. DNA-dir_RNA_pol_bsu_bac-type.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
Gene3DG3DSA:2.30.150.10. G3DSA:2.30.150.10. 1 hit.
G3DSA:2.40.270.10. G3DSA:2.40.270.10. 2 hits.
G3DSA:2.40.50.150. Ribosomal_L2. 2 hits.
KOK03043.
PANTHERPTHR20856:SF3. PTHR20856:SF3. 1 hit.
PTHR20856. RNA_pol_I_sub2. 1 hit.
PfamPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsTIGR02013. RpoB. 1 hit.
PROSITEPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9L7J6_NAUPA
AccessionPrimary (citable) accession number: B9L7J6
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info