B9L789 (DCD_NAUPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	NAMH_0055

Organism

Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH) [Complete proteome] [HAMAP]

Taxonomic identifier

598659 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Nautiliales › Nautiliaceae › Nautilia › Nautilia profundicola

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000123154

Sequences

	Sequence		Length	Mass (Da)
	B9L789 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 89FA69EF84554FF5	FASTA	186	20,811
	10 20 30 40 50 60 MGVKSDIWIR NMAKNFNMIS PFEEKQVRKG IISYGVSSYG YDIRVSDEFM VFTNINSTVV 70 80 90 100 110 120 DPKNFDERNV VNIKGDCIIP PNSFALCRSV EYFKMPRDVL AICVGKSTYA RCGIIVNVTP 130 140 150 160 170 180 IEPEWEGHIT IEISNTTPLP AKIYANEGIA QLIFLGADDN ICETSYADKS GKYHGQKGIT LPKVDK

References

[1]

"Adaptations to submarine hydrothermal environments exemplified by the genome of Nautilia profundicola." Campbell B.J., Smith J.L., Hanson T.E., Klotz M.G., Stein L.Y., Lee C.K., Wu D., Robinson J.M., Khouri H.M., Eisen J.A., Cary S.C. PLoS Genet. 5:E1000362-E1000362(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1463 / DSM 18972 / AmH.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001279 Genomic DNA. Translation: ACM93710.1.
RefSeq	YP_002606497.1. NC_012115.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	598659.NAMH_0055.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACM93710; ACM93710; NAMH_0055.
GeneID	7505072.
KEGG	nam:NAMH_0055.
PATRIC	22674829. VBINauPro131435_0055.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228600.
KO	K01494.
OMA	RSVLTVC.
Enzyme and pathway databases
BioCyc	NPRO598659:GH7N-1653-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_NAUPA

Accession

Primary (citable) accession number: B9L789

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program