B9L0I6 (B9L0I6_THERP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Name:	ald EMBL ACM04617.1
Ordered Locus Names:	trd_1056

Organism

Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2) [Complete proteome] [HAMAP]

Taxonomic identifier

309801 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Thermomicrobiales › Thermomicrobiaceae › Thermomicrobium

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183 EMBL ACM04617.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B9L0I6 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 375B9F9406091C9D	FASTA	375	40,525
	10 20 30 40 50 60 MGGRALIIGI PRERKLREYR VAQPPHGVRE LVRHGHRVLV ERGAGVGSGF TDTDYEAAGA 70 80 90 100 110 120 ELVDDAEAVW SQSEMIVKVK EPIESEYRFL RPGLILFTFL HLAADERLTR ELMAREVIAI 130 140 150 160 170 180 AYETVQLPDG SLPLLAPMSE VAGRLAIQVG AYYLMEPYGG RGVLLGGVPG VAPGRVVILG 190 200 210 220 230 240 GGTVGTNAAQ MALGLGADVL LFDINVERLR YLEQILHGRF QTRVSSEQVI GEAIREADLV 250 260 270 280 290 300 IGAVLIPGAR APKLVTRQMV RAMRPGSVIV DVSIDQGGCV ETARPTTHDA PVYDVDGVLH 310 320 330 340 350 360 YMVTNMPGAV PRTSTFALSN VTLRYVLELA DLGLVAAVQR DRALAKGVNV FRGRITHPSV 370 AESFGLPYVP LDELL

References

[1]

"Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum." Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A., Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L., Eisen J.A. PLoS ONE 4:E4207-E4207(2009) [PubMed: 19148287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001275 Genomic DNA. Translation: ACM04617.1.
RefSeq	YP_002522266.1. NC_011959.1.
3D structure databases
ProteinModelPortal	B9L0I6.
ModBase	Search...
Protein-protein interaction databases
STRING	B9L0I6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7355260.
GenomeReviews	Gene locus trd_1056 in contig CP001275_GR.
KEGG	tro:trd_1056.
PATRIC	23913284. VBITheRos91376_0993.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VAHGHEV.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B9L0I6_THERP

Accession

Primary (citable) accession number: B9L0I6

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)