B9KZZ4 (B9KZZ4_THERP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit beta HAMAP MF_01321
Short name=RNAP subunit beta HAMAP MF_01321
EC=2.7.7.6 HAMAP MF_01321

Alternative name(s):
RNA polymerase subunit beta HAMAP MF_01321
Transcriptase subunit beta HAMAP MF_01321

Gene names

Name:	rpoB HAMAP MF_01321 EMBL ACM06200.1
Ordered Locus Names:	trd_0991

Organism

Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2) [Complete proteome] [HAMAP]

Taxonomic identifier

309801 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Thermomicrobiales › Thermomicrobiaceae › Thermomicrobium

Protein attributes

Sequence length	1162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP MF_01321 RuleBase RU000432
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_01321
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity. HAMAP MF_01321 RuleBase RU000433
Sequence similarities	Belongs to the RNA polymerase beta chain family. HAMAP MF_01321 RuleBase RU000434

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase HAMAP MF_01321 EMBL ACM06200.1
Molecular function	Nucleotidyltransferase HAMAP MF_01321 EMBL ACM06200.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: HAMAP DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: HAMAP ribonucleoside binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B9KZZ4 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 6D603A0F9C31556B	FASTA	1,162	130,172
	10 20 30 40 50 60 MTVTTGATAM PSSAVRQVRS NLGIGRVSFA RIPTVLEMPN LIELQLKSFE WFKTEGLREL 70 80 90 100 110 120 LEEFSPIIDY NQKLEVHFLR HWFEKPRYTP EICRERDMTY AAPLYFRVRL VIRDTGEVKE 130 140 150 160 170 180 SDIYIDDFPM MTETGTFVIN GAERVVVSQL VRSPGAYFEL EPDPATGRQL CMAKLIPTRG 190 200 210 220 230 240 AWLEFETSNR DVLSVKIDRK RKIPVTVLLR AVGYGRDEEL FELFADVDTD PDHRYIAATI 250 260 270 280 290 300 ERDRTKSREE AQMEIYKTLR PGDPPTRENA AALIERLFFN PRTYDLGKVG RYKLNKRLGL 310 320 330 340 350 360 ETPADVRVLT REDLAALVRT MILVNRGLDR PDDIDHLGNR RVRTVGELIQ MHLRTGLQRL 370 380 390 400 410 420 ERGIRERMTI VDIDTATPAS LISSTRPLRA AIREFFAGSQ LSQFMDQTNP LAELTHKRRV 430 440 450 460 470 480 SALGPGGLNR ERAGFEVRDV HDSHYGRICP IETPEGPNIG LITSLATYAK VNEYGFITAP 490 500 510 520 530 540 YRRVYRHIEL PSQADLLIGQ VLRTDVVDPE TGELLAGRGT TVDRGLCDRL IAAGVTRVDV 550 560 570 580 590 600 LPFVSDEVDY LTADQEEHFT IAQANTPLDE GMRFVASRIE ARRAGKFVLE VPEKVDYMDV 610 620 630 640 650 660 SPKQVVSVSA ALIPFLEHDD ANRALMGANM QRQAVPLLRP RAPIVGTGVE YQAARDSGQV 670 680 690 700 710 720 VVAQKGGIVK SVTARRIVVL EDDGNERVYE LRKFVRSNQD TCINQRPIVQ KGQRIEAGDV 730 740 750 760 770 780 IADSSSTENG ELALGQNVLV AFMSWEGGNF EDAVLISERL VREDVYTSIH IEKYECEARD 790 800 810 820 830 840 TKLGPEEITR DIPNVGEDSL RNLDADGIIR IGAQVGPNDI LVGKVTPRGE TELSAEERLL 850 860 870 880 890 900 RAIFGERARD VKDTSLRVPH GVHGIVIDVK RFRRDDESGV ELPAGVNEMV RVFIAQKRKI 910 920 930 940 950 960 SEGDKMAGRH GNKGVVSRIV PIEDMPYLPD GTPVDIILNP IGVPSRMNLG QILETHLGWA 970 980 990 1000 1010 1020 AHTLGIKVAS PVFDGAKEEE IRELLRKAGL PEDGKVELYD GRTGEKFDRP VTVGIIYMMK 1030 1040 1050 1060 1070 1080 LVHLVEDKIH ARSTGPYSLV TQQPLGGKAQ FGGQRFGEME VWALEAYGAA HTLQEMLTVK 1090 1100 1110 1120 1130 1140 SDDVVGRVKT YEAIVKGEPI VEAGVPESFK VLVKELRSLG LSVEVLNEDE EPIEFGEDHG 1150 1160 REREILSHLD RINLSGFERT EE

References

[1]

"Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum." Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A., Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L., Eisen J.A. PLoS ONE 4:E4207-E4207(2009) [PubMed: 19148287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001275 Genomic DNA. Translation: ACM06200.1.
RefSeq	YP_002522208.1. NC_011959.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B9KZZ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7356433.
GenomeReviews	Gene locus trd_0991 in contig CP001275_GR.
KEGG	tro:trd_0991.
PATRIC	23913156. VBITheRos91376_0936.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	IGRNKTY.
ProtClustDB	PRK00405.
Family and domain databases
HAMAP	MF_01321. RNApol_bact_RpoB. [Tree]
InterPro	IPR010243. DNA-dir_RNA_pol_bsu_bac-type. IPR019462. DNA-dir_RNA_pol_bsu_external_1. IPR015712. DNA-dir_RNA_pol_su2. IPR007120. DNA-dir_RNA_pol_su2_6. IPR007121. RNA_pol_bsu_CS. IPR007644. RNA_pol_bsu_protrusion. IPR007642. RNA_pol_Rpb2_2. IPR007645. RNA_pol_Rpb2_3. IPR007641. RNA_pol_Rpb2_7. IPR014724. RNA_pol_RPB2_OB-fold. [Graphical view]
Gene3D	G3DSA:2.30.150.10. G3DSA:2.30.150.10. 1 hit. G3DSA:2.40.270.10. G3DSA:2.40.270.10. 2 hits. G3DSA:2.40.50.150. Ribosomal_L2. 1 hit.
KO	K03043.
PANTHER	PTHR20856:SF3. PTHR20856:SF3. 1 hit. PTHR20856. RNA_pol_I_sub2. 1 hit.
Pfam	PF04563. RNA_pol_Rpb2_1. 1 hit. PF04561. RNA_pol_Rpb2_2. 1 hit. PF04565. RNA_pol_Rpb2_3. 1 hit. PF10385. RNA_pol_Rpb2_45. 1 hit. PF00562. RNA_pol_Rpb2_6. 1 hit. PF04560. RNA_pol_Rpb2_7. 1 hit. [Graphical view]
PROSITE	PS01166. RNA_POL_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B9KZZ4_THERP

Accession

Primary (citable) accession number: B9KZZ4

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)