B9KXH9 (B9KXH9_THERP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006

Alternative name(s):
Arginosuccinase HAMAP MF_00006

Gene names

Name:	argH HAMAP MF_00006 EMBL ACM05556.1
Ordered Locus Names:	trd_0166

Organism

Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2) [Complete proteome] [HAMAP]

Taxonomic identifier

309801 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Thermomicrobiales › Thermomicrobiaceae › Thermomicrobium

Protein attributes

Sequence length	485 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm By similarity HAMAP MF_00006.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00006
Cellular component	Cytoplasm HAMAP MF_00006
Molecular function	Lyase HAMAP MF_00006 EMBL ACM05556.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B9KXH9 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 5281F31B87BCD67E	FASTA	485	54,029
	10 20 30 40 50 60 MTTPAKLWGG RFQKPTHELV DQLNASLPFD RRLARHDILG SLAHVTMLAQ RGIIPREDAQ 70 80 90 100 110 120 TIARGLRTIL REIEEERFAF RLADEDIHLS VERRLHELIG PVAGRLHTAR SRNDQVALDF 130 140 150 160 170 180 RLWMREALLE IAEGIVETSG ALLDLAELHR DVVMPGYTHL QRAQPVLFAH HVHAYVVMLT 190 200 210 220 230 240 RDLERLRQLY QRVNRSPLGS GALAGVPYPI DRHVVAALLA MDGVLENSID AVSDRDFALE 250 260 270 280 290 300 FLADLAILMA HLSRLAEELV LWSSSEFGFI EFDDAFATGS SIMPQKKNPD VAELLRGKSG 310 320 330 340 350 360 RVFGHLIGLL TVVKGLPLAY NKDLQEDKEG VFDAYDTVAL LLRVLPPMLR TLRINRERLE 370 380 390 400 410 420 AAAGQNFTLA TDIADALVRA GVPFREAHEA VGRLVAFCLA SGKSLDQLTA DELARFHSKL 430 440 450 460 470 480 AEITLPRTVW DAVRAREHLG GTGPEHVARA IAASRADSAG ARQWLESERQ RIEHAFARLL SEDVP

References

[1]

"Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum." Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A., Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L., Eisen J.A. PLoS ONE 4:E4207-E4207(2009) [PubMed: 19148287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001275 Genomic DNA. Translation: ACM05556.1.
RefSeq	YP_002521421.1. NC_011959.1.
3D structure databases
ProteinModelPortal	B9KXH9.
ModBase	Search...
Protein-protein interaction databases
STRING	B9KXH9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7355684.
GenomeReviews	Gene locus trd_0166 in contig CP001275_GR.
KEGG	tro:trd_0166.
PATRIC	23911556. VBITheRos91376_0166.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EDIHTVI.
ProtClustDB	CLSK2807412.
Family and domain databases
HAMAP	MF_00006. Arg_succ_lyase. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view]
KO	K01755.
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. ArgH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B9KXH9_THERP

Accession

Primary (citable) accession number: B9KXH9

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)