B9KXB9 (B9KXB9_THERP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134 EMBL ACM06153.1
Ordered Locus Names:	trd_0105

Organism

Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2) [Complete proteome] [HAMAP]

Taxonomic identifier

309801 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Thermomicrobiales › Thermomicrobiaceae › Thermomicrobium

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B9KXB9 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: D409B33457566AC5	FASTA	275	29,306
	10 20 30 40 50 60 MTRTGTVLDR IVERTSADLA ERRRRVPEGA LRAQAHEQAP PVPLVPALRA DRVSVIAEVK 70 80 90 100 110 120 RGSPSRGLFA PEADAAAVAM DYLAGGAAAL SVLTDEPFFH GSLKDLAVVA RLAHASPGPV 130 140 150 160 170 180 PVLRKDFLLD PYQIVEARAH GADAVLLIVA VLDRWQLAEL LGVTWELGME ALVEVHDESE 190 200 210 220 230 240 LATAVEAGAR VIGINNRDLR TFTVDLTVSE RLAPLVPADR VVVAESGIHS VADVERLARA 250 260 270 GIDAILVGEA LMMAPDRRAI VQALGSVEVV RCRGS

References

[1]

"Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum." Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A., Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L., Eisen J.A. PLoS ONE 4:E4207-E4207(2009) [PubMed: 19148287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001275 Genomic DNA. Translation: ACM06153.1.
RefSeq	YP_002521361.1. NC_011959.1.
3D structure databases
ProteinModelPortal	B9KXB9.
ModBase	Search...
Protein-protein interaction databases
STRING	B9KXB9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7355411.
GenomeReviews	Gene locus trd_0105 in contig CP001275_GR.
KEGG	tro:trd_0105.
PATRIC	23911438. VBITheRos91376_0108.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FETDINT.
ProtClustDB	CLSK2807401.
Family and domain databases
HAMAP	MF_00134_A. IGPS_A. [Tree] MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B9KXB9_THERP

Accession

Primary (citable) accession number: B9KXB9

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)