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B9KTD9 (IOLG_RHOSK) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inositol 2-dehydrogenase

EC=1.1.1.18
Alternative name(s):
Myo-inositol 2-dehydrogenase
Short name=MI 2-dehydrogenase
Gene names
Name:iolG
Ordered Locus Names:RSKD131_3457
OrganismRhodobacter sphaeroides (strain KD131 / KCTC 12085) [Complete proteome] [HAMAP]
Taxonomic identifier557760 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP-Rule MF_01671

Catalytic activity

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP-Rule MF_01671

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01671

Sequence similarities

Belongs to the Gfo/Idh/MocA family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processinositol catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functioninositol 2-dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 334334Inositol 2-dehydrogenase HAMAP-Rule MF_01671
PRO_1000187320

Sequences

Sequence LengthMass (Da)Tools
B9KTD9 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 7995F14670D96FF7

FASTA33436,099
        10         20         30         40         50         60 
MTLRIGIIGT GAIGTDHARR INRVLSGAEV TAVTDVNRDN AEACVAGVAP GAQILGSAEE 

        70         80         90        100        110        120 
VIAASDAVLV CSWGAAHEAQ VLAAIAAGKP CFCEKPLATE AYGARRIVEA EEAMGRRLVQ 

       130        140        150        160        170        180 
VGFMRRYDRG YVALKETVRT RLGPPLMIHA AHRNPTVPGR YRTPMAIHDT LIHEIDVLRW 

       190        200        210        220        230        240 
LLDDEYVSAQ VIFPRATRHT HAGLRDPQIV LLETAKGVRI DVEIFVNCRY GYDIQCEVVG 

       250        260        270        280        290        300 
EEGTARLPEP TAIPTRLGAV FGQPILMDWK DRFIDSYDVE LQDFLKAAAQ GTAAGPSAWD 

       310        320        330 
GYVAAITADV CAQAQERPGA ILPVTLPARP ALYA 

« Hide

References

[1]"Complete genome sequence of Rhodobacter sphaeroides KD131."
Lim S.-K., Kim S.J., Cha S.H., Oh Y.-K., Rhee H.-J., Kim M.-S., Lee J.K.
J. Bacteriol. 191:1118-1119(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KD131 / KCTC 12085.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001151 Genomic DNA. Translation: ACM03317.1.
RefSeqYP_002520390.1. NC_011958.1.

3D structure databases

ProteinModelPortalB9KTD9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING557760.RSKD131_3457.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM03317; ACM03317; RSKD131_3457.
GeneID7353453.
KEGGrsk:RSKD131_3457.
PATRIC23176913. VBIRhoSph125910_0350.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0673.
HOGENOMHOG000227439.
KOK00010.
OMACFCEKPL.
OrthoDBEOG6GFGMS.

Enzyme and pathway databases

BioCycRSPH557760:GH1P-3509-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_01671. IolG.
InterProIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIOLG_RHOSK
AccessionPrimary (citable) accession number: B9KTD9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families