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Protein

Inositol 2-dehydrogenase

Gene

iolG

Organism
Rhodobacter sphaeroides (strain KD131 / KCTC 12085)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).UniRule annotation

Catalytic activityi

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRSPH557760:GH1P-3509-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol 2-dehydrogenaseUniRule annotation (EC:1.1.1.18UniRule annotation)
Alternative name(s):
Myo-inositol 2-dehydrogenaseUniRule annotation
Short name:
MI 2-dehydrogenaseUniRule annotation
Gene namesi
Name:iolGUniRule annotation
Ordered Locus Names:RSKD131_3457
OrganismiRhodobacter sphaeroides (strain KD131 / KCTC 12085)
Taxonomic identifieri557760 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
ProteomesiUP000001597 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 334334Inositol 2-dehydrogenasePRO_1000187320Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi557760.RSKD131_3457.

Structurei

3D structure databases

ProteinModelPortaliB9KTD9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0673.
HOGENOMiHOG000227439.
KOiK00010.
OMAiGRMGADH.
OrthoDBiEOG6GFGMS.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9KTD9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRIGIIGT GAIGTDHARR INRVLSGAEV TAVTDVNRDN AEACVAGVAP
60 70 80 90 100
GAQILGSAEE VIAASDAVLV CSWGAAHEAQ VLAAIAAGKP CFCEKPLATE
110 120 130 140 150
AYGARRIVEA EEAMGRRLVQ VGFMRRYDRG YVALKETVRT RLGPPLMIHA
160 170 180 190 200
AHRNPTVPGR YRTPMAIHDT LIHEIDVLRW LLDDEYVSAQ VIFPRATRHT
210 220 230 240 250
HAGLRDPQIV LLETAKGVRI DVEIFVNCRY GYDIQCEVVG EEGTARLPEP
260 270 280 290 300
TAIPTRLGAV FGQPILMDWK DRFIDSYDVE LQDFLKAAAQ GTAAGPSAWD
310 320 330
GYVAAITADV CAQAQERPGA ILPVTLPARP ALYA
Length:334
Mass (Da):36,099
Last modified:March 24, 2009 - v1
Checksum:i7995F14670D96FF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001151 Genomic DNA. Translation: ACM03317.1.
RefSeqiWP_012641034.1. NC_011958.1.
YP_002520390.1. NC_011958.1.

Genome annotation databases

EnsemblBacteriaiACM03317; ACM03317; RSKD131_3457.
KEGGirsk:RSKD131_3457.
PATRICi23176913. VBIRhoSph125910_0350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001151 Genomic DNA. Translation: ACM03317.1.
RefSeqiWP_012641034.1. NC_011958.1.
YP_002520390.1. NC_011958.1.

3D structure databases

ProteinModelPortaliB9KTD9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi557760.RSKD131_3457.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACM03317; ACM03317; RSKD131_3457.
KEGGirsk:RSKD131_3457.
PATRICi23176913. VBIRhoSph125910_0350.

Phylogenomic databases

eggNOGiCOG0673.
HOGENOMiHOG000227439.
KOiK00010.
OMAiGRMGADH.
OrthoDBiEOG6GFGMS.

Enzyme and pathway databases

BioCyciRSPH557760:GH1P-3509-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Rhodobacter sphaeroides KD131."
    Lim S.-K., Kim S.J., Cha S.H., Oh Y.-K., Rhee H.-J., Kim M.-S., Lee J.K.
    J. Bacteriol. 191:1118-1119(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KD131 / KCTC 12085.

Entry informationi

Entry nameiIOLG_RHOSK
AccessioniPrimary (citable) accession number: B9KTD9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: April 29, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.