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B9KSJ9 (AROB_RHOSK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:RSKD131_1146
OrganismRhodobacter sphaeroides (strain KD131 / KCTC 12085) [Complete proteome] [HAMAP]
Taxonomic identifier557760 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3703703-dehydroquinate synthase HAMAP MF_00110
PRO_1000119087

Sequences

Sequence LengthMass (Da)Tools
B9KSJ9 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: A981C48F56548DA8

FASTA37039,410
        10         20         30         40         50         60 
MTVDAVRVEL GARAYEVRIG PGLIARAGAE IAPLLRRPKV AILTDETVAG LHLDPFRQAL 

        70         80         90        100        110        120 
VEAGIASSAL ALPAGEATKG WPQFARAVEW LLEEKVERRD VVVALGGGVI GDLAGFAAAV 

       130        140        150        160        170        180 
LRRGVRFVQV PTTLLAQVDS SVGGKTGINT AQGKNLVGAF HQPSLVLADI GVLETLPPRD 

       190        200        210        220        230        240 
FRAGYGEVVK YGLLGDADFY EWLEGAGPRL AADAEARQRA VRRSVEMKAE IVARDETEEG 

       250        260        270        280        290        300 
DRALLNLGHT FCHALEKATG YSDRLLHGEG VAIGCALAFE LSQRLGLCAQ EAPSRLRAHL 

       310        320        330        340        350        360 
RAMGMKVDLR DIPGDLPSAE ALLALMAQDK KVVDGKLRFI LARGIGQAFV ADDVPGDVVR 

       370 
ALLEDALAER

« Hide

References

[1]"Complete genome sequence of Rhodobacter sphaeroides KD131."
Lim S.-K., Kim S.J., Cha S.H., Oh Y.-K., Rhee H.-J., Kim M.-S., Lee J.K.
J. Bacteriol. 191:1118-1119(2009) [PubMed: 19028901] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KD131 / KCTC 12085.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001150 Genomic DNA. Translation: ACM01006.1.
RefSeqYP_002525507.1. NC_011963.1.

3D structure databases

ProteinModelPortalB9KSJ9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9KSJ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7358214.
GenomeReviewsGene locus RSKD131_1146 in contig CP001150_GR.
KEGGrsk:RSKD131_1146.
PATRIC23181389. VBIRhoSph125910_2556.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVMALEMS.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_RHOSK
AccessionPrimary (citable) accession number: B9KSJ9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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