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B9KS98 (B9KS98_RHOSK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH HAMAP MF_00191
Ordered Locus Names:RSKD131_3066
OrganismRhodobacter sphaeroides (strain KD131 / KCTC 12085) [Complete proteome] [HAMAP]
Taxonomic identifier557760 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length350 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191 SAAS SAAS003451

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191 SAAS SAAS003451

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191 SAAS SAAS003451

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
B9KS98 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 6CE72C42C3A1E6EA

FASTA35038,142
        10         20         30         40         50         60 
MRHPEADAPA GLDLSHRSEY LWAAQDEESR PMTMPPLTLY LAAPRGFCAG VDRAIKIVEM 

        70         80         90        100        110        120 
ALEKWGSPVY VRHEIVHNKF VVDRLRDMGA VFVEELDEAP TDRPVIFSAH GVPKAIPAEA 

       130        140        150        160        170        180 
ERRNMVYVDA TCPLVSKVHL EAERHHENGL QMIMIGHAGH PETVGTMGQL PEGEVLLVET 

       190        200        210        220        230        240 
VEDVAGLEVR DPERLAYITQ TTLSIDDTAA IVAALRERFP AIAIPRKEDI CYATTNRQGA 

       250        260        270        280        290        300 
VKAIAGRIDA LLVIGAPNSS NSKRLVEVGR AAGCRVAQLV QRATDIDWEA LQGATAVGVA 

       310        320        330        340        350 
AGASAPEVLV DEVIAAFCAR FDTTVEAVET VKERVEFKVP RILREPAETP

« Hide

References

[1]"Complete genome sequence of Rhodobacter sphaeroides KD131."
Lim S.-K., Kim S.J., Cha S.H., Oh Y.-K., Rhee H.-J., Kim M.-S., Lee J.K.
J. Bacteriol. 191:1118-1119(2009) [PubMed: 19028901] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001150 Genomic DNA. Translation: ACM02926.1.
RefSeqYP_002527427.1. NC_011963.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9KS98.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7359124.
GenomeReviewsGene locus RSKD131_3066 in contig CP001150_GR.
KEGGrsk:RSKD131_3066.
PATRIC23185286. VBIRhoSph125910_4472.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAEENIAFP.
ProtClustDBPRK01045.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB9KS98_RHOSK
AccessionPrimary (citable) accession number: B9KS98
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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