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B9KP68 (B9KP68_RHOSK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase 2 HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase 2 HAMAP MF_00315
Gene names
Name:dxs2 HAMAP MF_00315
Ordered Locus Names:RSKD131_2530
OrganismRhodobacter sphaeroides (strain KD131 / KCTC 12085) [Complete proteome] [HAMAP]
Taxonomic identifier557760 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length637 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B9KP68 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 0848D2CE90FA0A25

FASTA63767,590
        10         20         30         40         50         60 
MTDRPCTPTL DRVTLPVDMK GLTDRELRSL ADELRAETIS AVSVTGGHLG AGLGVVELTV 

        70         80         90        100        110        120 
ALHAVFDAPR DKIIWDVGHQ CYPHKILTGR RDRIRTLRQG GGLSGFTKRS ESPYDCFGAG 

       130        140        150        160        170        180 
HSSTSISAAV GFAAAREMGG DTGDAVAVIG DGSMSAGMAF EALNHGGHLK NRVIVILNDN 

       190        200        210        220        230        240 
EMSIAPPVGA LSSYLSRLYA GAPFQDFKAA AKGALGLLPE PFQEGARRAK EMLKSVTVGG 

       250        260        270        280        290        300 
TLFEELGFSY VGPIDGHDLD QLLPVLRTVK QRAHAPVLIH VITKKGRGYA PAEAARDRGH 

       310        320        330        340        350        360 
ATNKFNVLTG AQVKPVSNAP SYTKVFAQSL IKEAEVDERI CAVTAAMPDG TGLNLFGERF 

       370        380        390        400        410        420 
PKRTFDVGIA EQHAVTFSAA LAAGGMRPFC AIYSTFLQRG YDQIVHDVAI QRLPVRFAID 

       430        440        450        460        470        480 
RAGLVGADGA THAGSFDVAF LSNLPGIVVM AAADEAELVH MVATAAAHDE GPIAFRYPRG 

       490        500        510        520        530        540 
DGVGVEMPVK GVPLQIGRGR VVREGTRIAL LSFGTRLAEV QVAAEALAAR GISPTVADAR 

       550        560        570        580        590        600 
FAKPLDRDLI LQLAAHHEAL ITIEEGAIGG FGSHVAQLLA EAGVFDRGFR YRSMVLPDTF 

       610        620        630 
IDHNSAEVMY ATAGLNAADI ERKALETLGV EVLARRA

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References

[1]"Complete genome sequence of Rhodobacter sphaeroides KD131."
Lim S.-K., Kim S.J., Cha S.H., Oh Y.-K., Rhee H.-J., Kim M.-S., Lee J.K.
J. Bacteriol. 191:1118-1119(2009) [PubMed: 19028901] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001150 Genomic DNA. Translation: ACM02390.1.
RefSeqYP_002526891.1. NC_011963.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9KP68.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7359228.
GenomeReviewsGene locus RSKD131_2530 in contig CP001150_GR.
KEGGrsk:RSKD131_2530.
PATRIC23184190. VBIRhoSph125910_3936.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAEAMNAHA.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9KP68_RHOSK
AccessionPrimary (citable) accession number: B9KP68
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info